Optimizing Antibody Affinity and Developability Using a Framework–CDR Shuffling Approach—Application to an Anti-SARS-CoV-2 Antibody

por Gopal, Ranjani, Fitzpatrick, Emmett, Pentakota, Niharika, Jayaraman, Akila, Tharakaraman, Kannan, Capila, Ishan
Publicado 2022

Orthogonal immunoassays for IgG antibodies to SARS-CoV-2 antigens reveal that immune response lasts beyond 4 mo post illness onset

por Sasisekharan, Varun, Pentakota, Niharika, Jayaraman, Akila, Tharakaraman, Kannan, Wogan, Gerald N., Narayanasami, Uma
Publicado 2021

Enhancing antibody affinity through experimental sampling of non-deleterious CDR mutations predicted by machine learning

por Clark, Thomas, Subramanian, Vidya, Jayaraman, Akila, Fitzpatrick, Emmett, Gopal, Ranjani, Pentakota, Niharika, Rurak, Troy, Anand, Shweta, Viglione, Alexander, Raman, Rahul, Tharakaraman, Kannan, Sasisekharan, Ram
Publicado 2023