Cost-effective HRMA pre-sequence typing of clone libraries; application to phage display selection

por Pepers, Barry A, Schut, Menno H, Vossen, Rolf HAM, van Ommen, Gert-Jan B, den Dunnen, Johan T, van Roon-Mom, Willeke MC
Publicado 2009

Mutant huntingtin activates Nrf2-responsive genes and impairs dopamine synthesis in a PC12 model of Huntington's disease

por van Roon-Mom, Willeke MC, Pepers, Barry A, 't Hoen, Peter AC, Verwijmeren, Carola ACM, den Dunnen, Johan T, Dorsman, Josephine C, van Ommen, GertJan B
Publicado 2008

Making (anti-) sense out of huntingtin levels in Huntington disease

por Evers, Melvin M, Schut, Menno H, Pepers, Barry A, Atalar, Melek, van Belzen, Martine J, Faull, Richard LM, Roos, Raymund AC, van Roon-Mom, Willeke MC
Publicado 2015

Amyloid beta accumulations and enhanced neuronal differentiation in cerebral organoids of Dutch-type cerebral amyloid angiopathy patients

por Daoutsali, Elena, Pepers, Barry A., Stamatakis, Stavros, van der Graaf, Linda M., Terwindt, Gisela M., Parfitt, David A., Buijsen, Ronald A. M., van Roon-Mom, Willeke M. C.
Publicado 2023

Antisense Oligonucleotide-Induced Amyloid Precursor Protein Splicing Modulation as a Therapeutic Approach for Dutch-Type Cerebral Amyloid Angiopathy

por Daoutsali, Elena, Hailu, Tsinatkeab T., Buijsen, Ronald A.M., Pepers, Barry A., van der Graaf, Linda M., Verbeek, Marcel M., Curtis, Daniel, de Vlaam, Thomas, van Roon-Mom, Willeke M.C.
Publicado 2021

Targeting Several CAG Expansion Diseases by a Single Antisense Oligonucleotide

por Evers, Melvin M., Pepers, Barry A., van Deutekom, Judith C. T., Mulders, Susan A. M., den Dunnen, Johan T., Aartsma-Rus, Annemieke, van Ommen, Gert-Jan B., van Roon-Mom, Willeke M. C.
Publicado 2011

Selection and characterization of llama single domain antibodies against N-terminal huntingtin

por Schut, Menno H., Pepers, Barry A., Klooster, Rinse, van der Maarel, Silvère M., el Khatabi, Mohamed, Verrips, Theo, den Dunnen, Johan T., van Ommen, Gert-Jan B., van Roon-Mom, Willeke M. C.
Publicado 2014

Effect of post-mortem delay on N-terminal huntingtin protein fragments in human control and Huntington disease brain lysates

por Schut, Menno H., Patassini, Stefano, Kim, Eric H., Bullock, Jocelyn, Waldvogel, Henry J., Faull, Richard L. M., Pepers, Barry A., den Dunnen, Johan T., van Ommen, Gert-Jan B., van Roon-Mom, Willeke M. C.
Publicado 2017

Underlying molecular mechanisms of DIO2 susceptibility in symptomatic osteoarthritis

por Bomer, Nils, den Hollander, Wouter, Ramos, Yolande F M, Bos, Steffan D, van der Breggen, Ruud, Lakenberg, Nico, Pepers, Barry A, van Eeden, Annelies E, Darvishan, Arash, Tobi, Elmar W, Duijnisveld, Bouke J, van den Akker, Erik B, Heijmans, Bastiaan T, van Roon-Mom, Willeke MC, Verbeek, Fons J, van Osch, Gerjo J V M, Nelissen, Rob G H H, Slagboom, P Eline, Meulenbelt, Ingrid
Publicado 2015