The anti-Müllerian hormone prodomain is displaced from the hormone/prodomain complex upon bivalent binding to the hormone receptor

por Cate, Richard L., di Clemente, Nathalie, Racine, Chrystèle, Groome, Nigel P., Pepinsky, R. Blake, Whitty, Adrian
Publicado 2021

Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-β

por Arndt, Joseph W., Qian, Fang, Smith, Benjamin A., Quan, Chao, Kilambi, Krishna Praneeth, Bush, Martin W., Walz, Thomas, Pepinsky, R. Blake, Bussière, Thierry, Hamann, Stefan, Cameron, Thomas O., Weinreb, Paul H.
Publicado 2018

Functional activity of anti-LINGO-1 antibody opicinumab requires target engagement at a secondary binding site

por Hanf, Karl J. M., Arndt, Joseph W., Liu, YuTing, Gong, Bang Jian, Rushe, Mia, Sopko, Richelle, Massol, Ramiro, Smith, Benjamin, Gao, Yan, Dalkilic-Liddle, Isin, Lee, Xinhua, Mojta, Shanell, Shao, Zhaohui, Mi, Sha, Pepinsky, R. Blake
Publicado 2020