Protein Delivery of Cell-Penetrating Zinc-Finger Activators Stimulates Latent HIV-1-Infected Cells

por Perdigão, Pedro R.L., Cunha-Santos, Catarina, Barbas, Carlos F., Santa-Marta, Mariana, Goncalves, Joao
Publicado 2020

Retinal Organoids from an AIPL1 CRISPR/Cas9 Knockout Cell Line Successfully Recapitulate the Molecular Features of LCA4 Disease

por Perdigão, Pedro R. L., Ollington, Bethany, Sai, Hali, Leung, Amy, Sacristan-Reviriego, Almudena, van der Spuy, Jacqueline
Publicado 2023

CRISPR-Cas9 correction of OPA1 c.1334G>A: p.R445H restores mitochondrial homeostasis in dominant optic atrophy patient-derived iPSCs

por Sladen, Paul E., Perdigão, Pedro R.L., Salsbury, Grace, Novoselova, Tatiana, van der Spuy, Jacqueline, Chapple, J. Paul, Yu-Wai-Man, Patrick, Cheetham, Michael E.
Publicado 2021

Extracellular communication between brain cells through functional transfer of Cre mRNA

por Rufino-Ramos, David, Leandro, Kevin, Perdigão, Pedro R.L., O’Brien, Killian, Pinto, Maria Manuel, Santana, Magda M., van Solinge, Thomas S, Mahjoum, Shadi, Breakefield, Xandra O, Breyne, Koen, de Almeida, Luís Pereira
Publicado 2023

Investigation of PTC124-mediated translational readthrough in a retinal organoid model of AIPL1-associated Leber congenital amaurosis

por Leung, Amy, Sacristan-Reviriego, Almudena, Perdigão, Pedro R.L., Sai, Hali, Georgiou, Michalis, Kalitzeos, Angelos, Carr, Amanda-Jayne F., Coffey, Peter J., Michaelides, Michel, Bainbridge, James, Cheetham, Michael E., van der Spuy, Jacqueline
Publicado 2022

CRISPR-Cas9 correction of a nonsense mutation in LCA5 rescues lebercilin expression and localization in human retinal organoids

por Afanasyeva, Tess A.V., Athanasiou, Dimitra, Perdigao, Pedro R.L., Whiting, Kae R., Duijkers, Lonneke, Astuti, Galuh D.N., Bennett, Jean, Garanto, Alejandro, van der Spuy, Jacqueline, Roepman, Ronald, Cheetham, Michael E., Collin, Rob W.J.
Publicado 2023