High ME1 Expression Is a Molecular Predictor of Post-Transplant Survival of Patients with Acute Myeloid Leukemia

por Ortiz Rojas, César Alexander, Costa-Neto, Abel, Pereira-Martins, Diego A., Le, Duy Minh, Sternadt, Dominique, Weinhäuser, Isabel, Huls, Gerwin, Schuringa, Jan Jacob, Magalhães Rego, Eduardo
Publicado 2022

Association of HMIP1 C-893A polymorphism and disease severity in patients with sickle cell anemia

por Pereira-Martins, Diego A., Domingos, Igor F., Belini-Junior, Edis, Coelho-Silva, Juan L., Weinhäuser, Isabel, Araújo, Aderson S., Lobo, Clarisse L., Bonini-Domingos, Claudia R., Bezerra, Marcos A., Lucena-Araujo, Antonio R.
Publicado 2021

PB1826: CELLULAR AND MOLECULAR CHARACTERIZATION OF THE ANTINEOPLASTIC EFFECTS OF CEPHALOCHROMIN IN MODELS OF ACUTE MYELOID LEUKEMIA

por Nascimento, Mariane Cristina Do, Pereira-Martins, Diego A, Alcântara, Guilherme Augusto Sousa, Lima, Keli, Vicari, Hugo Passos, Ferreira, Marcelo José Pena, Costa-Lotufo, Leticia Leticia Veras, Neto, João Agostinho Machado, Rego, Eduardo Magalhães
Publicado 2023

Molecular-Based Score inspired on metabolic signature improves prognostic stratification for myelodysplastic syndrome

por Coelho-Silva, Juan L., Silveira, Douglas R. A., Pereira-Martins, Diego A., Rojas, Cesar A. O., Lucena-Araujo, Antonio R., Rego, Eduardo M., Machado-Neto, João A., Bendit, Israel, Rocha, Vanderson, Traina, Fabiola
Publicado 2021

P466: THE INTRINSICALLY DISORDERED TRANSCRIPTIONAL REGULATOR MN1 DEPENDS ON THE CHAPERONE DNAJB6B FOR ITS FULL TRANSFORMING POTENTIAL

por Pereira-Martins, Diego A, van den Boom, Vincent, van Dijk, Noortje, Weinhauser, Isabel, Silveira, Douglas, M Bianco, Thiago, Alexander Ortiz Rojas, César, Huls, Gerwin, Quek, Lynn, R Lucena-Araujo, Antonio, Rego, Eduardo, Jacob Schuringa, Jan
Publicado 2023

Inhibition of the succinyl dehydrogenase complex in acute myeloid leukemia leads to a lactate-fuelled respiratory metabolic vulnerability

por Erdem, Ayşegül, Marin, Silvia, Pereira-Martins, Diego A., Geugien, Marjan, Cunningham, Alan, Pruis, Maurien G., Weinhäuser, Isabel, Gerding, Albert, Bakker, Barbara M., Wierenga, Albertus T. J., Rego, Eduardo M., Huls, Gerwin, Cascante, Marta, Schuringa, Jan Jacob
Publicado 2022

S127: DELTATP73 IMPOSES TP53 MUTANT-LIKE PHENOTYPES INCLUDING DRUG RESISTANCE AND POOR PROGNOSIS ON TP53-WILD TYPE ACUTE MYELOID LEUKEMIA.

por Pereira-Martins, Diego A, Alexander Ortiz Rojas, César, Weinhauser, Isabel, Silveira, Douglas, Wierenga, Albertus T J, van den Boom, Vincent, Bianco, Thiago M, Ammatuna, Emanuele, Quek, Lynn, Lucena-Araujo, Antonio R, Huls, Gerwin, Rego, Eduardo, Jacob Schuringa, Jan
Publicado 2023

MLL5 improves ATRA driven differentiation and promotes xenotransplant engraftment in acute promyelocytic leukemia model

por Pereira-Martins, Diego A., Weinhäuser, Isabel, Coelho-Silva, Juan Luiz, França-Neto, Pedro L., Almeida, Luciana Y., Bianco, Thiago M., Silva, Cleide L., França, Rafael F., Traina, Fabiola, Rego, Eduardo M., Schuringa, Jan Jacob, Lucena-Araujo, Antonio R.
Publicado 2021

The Glycolytic Gatekeeper PDK1 defines different metabolic states between genetically distinct subtypes of human acute myeloid leukemia

por Erdem, Ayşegül, Marin, Silvia, Pereira-Martins, Diego A., Cortés, Roldán, Cunningham, Alan, Pruis, Maurien G., de Boer, Bauke, van den Heuvel, Fiona A. J., Geugien, Marjan, Wierenga, Albertus T. J., Brouwers-Vos, Annet Z., Rego, Eduardo M., Huls, Gerwin, Cascante, Marta, Schuringa, Jan Jacob
Publicado 2022

ΔNp73 overexpression promotes resistance to apoptosis but does not cooperate with PML/RARA in the induction of an APL-leukemic phenotype

por Lucena-Araujo, Antonio R., Coelho-Silva, Juan L., Pereira-Martins, Diego A., Thomé, Carolina, Scheucher, Priscila S., Lange, Ana P., Paiva, Helder H., Hemmelgarn, Benjamin T., Morais-Sobral, Mariana C., Azevedo, Elisa A., Franca-Neto, Pedro L., Franca, Rafael F., Silva, Cleide L., Krause, Alexandre, Rego, Eduardo M.
Publicado 2016

The Combination of Gefitinib With ATRA and ATO Induces Myeloid Differentiation in Acute Promyelocytic Leukemia Resistant Cells

por de Almeida, Luciana Yamamoto, Pereira-Martins, Diego A., Weinhäuser, Isabel, Ortiz, César, Cândido, Larissa A., Lange, Ana Paula, De Abreu, Nayara F., Mendonza, Sílvia E. S., de Deus Wagatsuma, Virgínia M., Do Nascimento, Mariane C., Paiva, Helder H., Alves-Paiva, Raquel M., Bonaldo, Camila C. O. M., Nascimento, Daniele C., Alves-Filho, José C., Scheucher, Priscila S., Lima, Ana Sílvia G., Schuringa, Jan Jacob, Ammantuna, Emanuele, Ottone, Tiziana, Noguera, Nelida I., Araujo, Cleide L., Rego, Eduardo M.
Publicado 2021

Reduced SLIT2 is Associated with Increased Cell Proliferation and Arsenic Trioxide Resistance in Acute Promyelocytic Leukemia

por Weinhäuser, Isabel, Pereira-Martins, Diego A., Ortiz, Cesar, Silveira, Douglas R., Simões, Luíse A. A., Bianco, Thiago M., Araujo, Cleide L., Koury, Luisa C., Melo, Raul A. M., Bittencourt, Rosane I., Pagnano, Katia, Pasquini, Ricardo, Nunes, Elenaide C., Fagundes, Evandro M., Gloria, Ana B., Kerbauy, Fábio, Chauffaille, Maria de Lourdes, Keating, Armand, Tallman, Martin S., Ribeiro, Raul C., Dillon, Richard, Ganser, Arnold, Löwenberg, Bob, Valk, Peter, Lo-Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Ammatuna, Emanuele, Lucena-Araujo, Antonio R., Schuringa, Jan Jacob, Rego, Eduardo M.
Publicado 2020