Therapeutically actionable signaling node to rescue AURKA driven loss of primary cilia in VHL-deficient cells

por Chowdhury, Pratim, Perera, Dimuthu, Powell, Reid T., Talley, Tia, Tripathi, Durga Nand, Park, Yong Sung, Mancini, Michael A., Davies, Peter, Stephan, Clifford, Coarfa, Cristian, Dere, Ruhee
Publicado 2021

Author Correction: Therapeutically actionable signaling node to rescue AURKA driven loss of primary cilia in VHL-deficient cells

por Chowdhury, Pratim, Perera, Dimuthu, Powell, Reid T., Talley, Tia, Tripathi, Durga Nand, Park, Yong Sung, Mancini, Michael A., Davies, Peter, Stephan, Clifford, Coarfa, Cristian, Dere, Ruhee
Publicado 2021

Patients with Lung Cancer of Different Racial Backgrounds Harbor Distinct Immune Cell Profiles

por Xu, Yitian, Zhang, Licheng, Thaiparambil, Jose, Mai, Sunny, Perera, Dimuthu Nuwan, Zhang, Jilu, Pan, Ping-Ying, Coarfa, Cristian, Ramos, Kenneth, Chen, Shu-Hsia, El-Zein, Randa
Publicado 2022

Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin

por Mao, Hua, Li, Luge, Fan, Qiying, Angelini, Aude, Saha, Pradip K., Coarfa, Cristian, Rajapakshe, Kimal, Perera, Dimuthu, Cheng, Jizhong, Wu, Huaizhu, Ballantyne, Christie M., Sun, Zheng, Xie, Liang, Pi, Xinchun
Publicado 2021

Integrative metabolomics and transcriptomics analysis reveals novel therapeutic vulnerabilities in lung cancer

por Thaiparambil, Jose, Dong, Jianrong, Grimm, Sandra L., Perera, Dimuthu, Ambati, Chandra Shekar R., Putluri, Vasanta, Robertson, Matthew J., Patel, Tajhal D., Mistretta, Brandon, Gunaratne, Preethi H., Kim, Min P., Yustein, Jason T., Putluri, Nagireddy, Coarfa, Cristian, El‐Zein, Randa
Publicado 2022

BET proteolysis targeted chimera-based therapy of novel models of Richter Transformation-diffuse large B-cell lymphoma

por Fiskus, Warren, Mill, Christopher P., Perera, Dimuthu, Birdwell, Christine, Deng, Qing, Yang, Haopeng, Lara, Bernardo H., Jain, Nitin, Burger, Jan, Ferrajoli, Alessandra, Davis, John A., Saenz, Dyana T., Jin, Wendy, Coarfa, Cristian, Crews, Craig M., Green, Michael R., Khoury, Joseph D., Bhalla, Kapil N.
Publicado 2021

miR-30a Remodels Subcutaneous Adipose Tissue Inflammation to Improve Insulin Sensitivity in Obesity

por Koh, Eun-Hee, Chernis, Natasha, Saha, Pradip K., Xiao, Liuling, Bader, David A., Zhu, Bokai, Rajapakshe, Kimal, Hamilton, Mark P., Liu, Xia, Perera, Dimuthu, Chen, Xi, York, Brian, Trauner, Michael, Coarfa, Cristian, Bajaj, Mandeep, Moore, David D., Deng, Tuo, McGuire, Sean E., Hartig, Sean M.
Publicado 2018

Superior efficacy of cotreatment with BET protein inhibitor and BCL2 or MCL1 inhibitor against AML blast progenitor cells

por Fiskus, Warren, Cai, Tianyu, DiNardo, Courtney D., Kornblau, Steven M., Borthakur, Gautam, Kadia, Tapan M., Pemmaraju, Naveen, Bose, Prithviraj, Masarova, Lucia, Rajapakshe, Kimal, Perera, Dimuthu, Coarfa, Cristian, Mill, Christopher P., Saenz, Dyana T., Saenz, David N., Sun, Baohua, Khoury, Joseph D., Shen, Yu, Konopleva, Marina, Bhalla, Kapil N.
Publicado 2019

Esomeprazole enhances the effect of ionizing radiation to improve tumor control

por Hebert, Kassidy A., Jaramillo, Sergio, Yu, Wangjie, Wang, Min, Veeramachaneni, Ratna, Sandulache, Vlad C., Sikora, Andrew G., Bonnen, Mark D., Annapragada, Ananth V., Corry, David, Kheradmand, Farrah, Pandita, Raj K., Ludwig, Michelle S., Pandita, Tej K., Huang, Shixia, Coarfa, Cristian, Grimm, Sandra L., Perera, Dimuthu, Miles, George, Ghebre, Yohannes T.
Publicado 2021

Superior efficacy of co-targeting GFI1/KDM1A and BRD4 against AML and post-MPN secondary AML cells

por Fiskus, Warren, Mill, Christopher P., Nabet, Behnam, Perera, Dimuthu, Birdwell, Christine, Manshouri, Taghi, Lara, Bernardo, Kadia, Tapan M., DiNardo, Courtney, Takahashi, Koichi, Daver, Naval, Bose, Prithviraj, Masarova, Lucia, Pemmaraju, Naveen, Kornblau, Steven, Borthakur, Gautam, Montalban-Bravo, Guillermo, Manero, Guillermo Garcia, Sharma, Sunil, Stubbs, Matthew, Su, Xiaoping, Green, Michael R., Coarfa, Cristian, Verstovsek, Srdan, Khoury, Joseph D., Vakoc, Christopher R., Bhalla, Kapil N.
Publicado 2021