Overcoming Chimeric Antigen Receptor (CAR) Modified T-Cell Therapy Limitations in Multiple Myeloma

por García-Guerrero, Estefanía, Sierro-Martínez, Belén, Pérez-Simón, Jose Antonio
Publicado 2020

Differential Engraftment of Parental A20 PD-L1 WT and PD-L1 KO Leukemia Cells in Semiallogeneic Recipients in the Context of PD-L1/PD-1 Interaction and NK Cell-Mediated Hybrid Resi...

por del Rio, Maria-Luisa, Perez-Simon, Jose-Antonio, Rodriguez-Barbosa, Jose-Ignacio
Publicado 2022

The Role of TNFR2 and DR3 in the In Vivo Expansion of Tregs in T Cell Depleting Transplantation Regimens

por Rodriguez-Barbosa, Jose-Ignacio, Schneider, Pascal, Graca, Luis, Bühler, Leo, Perez-Simon, Jose-Antonio, del Rio, Maria-Luisa
Publicado 2020

A Conditional Mouse Mutant in the Tumor Suppressor SdhD Gene Unveils a Link between p21(WAF1/Cip1) Induction and Mitochondrial Dysfunction

por Millán-Uclés, África, Díaz-Castro, Blanca, García-Flores, Paula, Báez, Alicia, Pérez-Simón, José Antonio, López-Barneo, José, Piruat, José I.
Publicado 2014

The Dynamics of the Human Leukocyte Antigen Head Domain Modulates Its Recognition by the T-Cell Receptor

por García-Guerrero, Estefanía, Pérez-Simón, José Antonio, Sánchez-Abarca, Luis Ignacio, Díaz-Moreno, Irene, De la Rosa, Miguel A., Díaz-Quintana, Antonio
Publicado 2016

A phase II, prospective, randomized, open-label study of defibrotide added to standard-of-care prophylaxis for the prevention of acute graft-versus-host disease after allogeneic he...

por Hudspeth, Michelle, Mori, Shahram, Nachbaur, David, Perez-Simon, José Antonio, Stölzel, Friedrich, Riches, Marcie, Wu, Wendy, Zhang, Peixin, Agarwal, Shirali, Yakoub-Agha, Ibrahim
Publicado 2022

Genetic deletion of HVEM in a leukemia B cell line promotes a preferential increase of PD-1(-) stem cell-like T cells over PD-1(+) T cells curbing tumor progression

por del Rio, Maria-Luisa, de Juan, Carla Yago-Diez, Roncador, Giovanna, Caleiras, Eduardo, Álvarez-Esteban, Ramón, Pérez-Simón, José Antonio, Rodriguez-Barbosa, Jose-Ignacio
Publicado 2023

RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation

por Buchrieser, Julian, Oliva-Martin, Maria Jose, Moore, Michael D., Long, Joshua C. D., Cowley, Sally A., Perez-Simón, Jose Antonio, James, William, Venero, Jose Luis
Publicado 2018

Compassionate use of ruxolitinib in acute and chronic graft versus host disease refractory both to corticosteroids and extracorporeal photopheresis

por Sarmiento Maldonado, Mauricio, Ramírez Villanueva, Pablo, Bertín Cortes-Monroy, Pablo, Jara Arias, Veronica, Soto Donoso, Katherine, Uribe Gonzalez, Pablo, Ocqueteau Tachini, Mauricio, Perez-Simón, Jose Antonio
Publicado 2017

Sensitivity of hematopoietic stem cells to mitochondrial dysfunction by SdhD gene deletion

por Bejarano-García, José Antonio, Millán-Uclés, África, Rosado, Iván V, Sánchez-Abarca, Luís Ignacio, Caballero-Velázquez, Teresa, Durán-Galván, María José, Pérez-Simón, José Antonio, Piruat, José I
Publicado 2016

PTPN13 and β-Catenin Regulate the Quiescence of Hematopoietic Stem Cells and Their Interaction with the Bone Marrow Niche

por López-Ruano, Guillermo, Prieto-Bermejo, Rodrigo, Ramos, Teresa L., San-Segundo, Laura, Sánchez-Abarca, Luis Ignacio, Sánchez-Guijo, Fermín, Pérez-Simón, José Antonio, Sánchez-Yagüe, Jesús, Llanillo, Marcial, Hernández-Hernández, Ángel
Publicado 2015

Caspase-8 inhibition represses initial human monocyte activation in septic shock model

por Oliva-Martin, Maria Jose, Sanchez-Abarca, Luis Ignacio, Rodhe, Johanna, Carrillo-Jimenez, Alejandro, Vlachos, Pinelopi, Herrera, Antonio Jose, Garcia-Quintanilla, Albert, Caballero-Velazquez, Teresa, Perez-Simon, Jose Antonio, Joseph, Bertrand, Venero, Jose Luis
Publicado 2016

First-in-Human Phase I Study of Iadademstat (ORY-1001): A First-in-Class Lysine-Specific Histone Demethylase 1A Inhibitor, in Relapsed or Refractory Acute Myeloid Leukemia

por Salamero, Olga, Montesinos, Pau, Willekens, Christophe, Pérez-Simón, José Antonio, Pigneux, Arnaud, Récher, Christian, Popat, Rakesh, Carpio, Cecilia, Molinero, César, Mascaró, Cristina, Vila, Joaquim, Arévalo, M. Isabel, Maes, Tamara, Buesa, Carlos, Bosch, Francesc, Somervaille, Tim C. P.
Publicado 2020

First‐in‐human study of JNJ‐63709178, a CD123/CD3 targeting antibody, in relapsed/refractory acute myeloid leukemia

por Boyiadzis, Michael, Desai, Pinkal, Daskalakis, Nikki, Donnellan, William, Ferrante, Lucille, Goldberg, Jenna D., Grunwald, Michael R., Guttke, Christina, Li, Xiang, Perez‐Simon, Jose Antonio, Salamero, Olga, Tucker, Trevor, Xu, Xiaoying, Yang, Jay, Pemmaraju, Naveen, Alonso‐Dominguez, Juan Manuel
Publicado 2023

Mesenchymal Stromal Cells for Treating Steroid-Resistant Acute and Chronic Graft Versus Host Disease: A Multicenter Compassionate Use Experience

por Macías-Sánchez, María del Mar, Morata-Tarifa, Cynthia, Cuende, Natividad, Cardesa-Gil, Ana, Cuesta-Casas, María Ángeles, Pascual-Cascon, María Jesús, Pascual, Antonia, Martín-Calvo, Carmen, Jurado, Manuel, Perez-Simón, José Antonio, Espigado, Ildefonso, Garzón López, Sebastián, Carmona Sánchez, Gloria, Mata-Alcázar-Caballero, Rosario, Sánchez-Pernaute, Rosario
Publicado 2022

Long-Term Impact of an Educational Antimicrobial Stewardship Program on Management of Patients with Hematological Diseases

por Guisado-Gil, Ana Belén, Aguilar-Guisado, Manuela, Peñalva, Germán, Lepe, José Antonio, Espigado, Ildefonso, Rodríguez-Arbolí, Eduardo, González-Campos, José, Rodríguez-Torres, Nancy, Montero-Cuadrado, María Isabel, Falantes-González, José Francisco, Reguera-Ortega, Juan Luis, Gil-Navarro, María Victoria, Molina, José, Pérez-Simón, José-Antonio, Cisneros, José Miguel
Publicado 2021

Impact of Sars-CoV2 Infection on 491 Hematological Patients: The Ecovidehe Multicenter Study

por De Ramón, Cristina, Hernandez-Rivas, Jose Angel, Rodríguez García, Jose Antonio, Ocio, Enrique M., Gómez-Casares, María Teresa, López Jiménez, Javier, Solano, Carlos, Martínez-López, Joaquín, Sureda, Anna, Jurado, Manuel, Córdoba, Raul, Benavente, Celina, Marco, Pascual, Pérez-Simón, Jose Antonio, Moraleda, Jose Maria, Figuera, Angela, Pardal, Emilia, Pascual Izquierdo, Cristina, Garcia-Sanz, Ramon
Publicado 2020

Combined treatment of graft versus host disease using donor regulatory T cells and ruxolitinib

por Rodríguez-Gil, Alfonso, Escamilla-Gómez, Virginia, Nufer, Melanie, Andújar-Sánchez, Félix, Lopes-Ramos, Teresa, Bejarano-García, José Antonio, García-Guerrero, Estefanía, Calderón-Cabrera, Cristina, Caballero-Velázquez, Teresa, García-Calderón, Clara Beatriz, Hernández-Díaz, Paola, Reguera-Ortega, Juan Luis, Rodríguez-Torres, Nancy, Martínez-Cibrián, Nuria, Rodríguez-Barbosa, José Ignacio, Villadiego, Javier, Pérez-Simón, José Antonio
Publicado 2022

IMiDs mobilize acute myeloid leukemia blasts to peripheral blood through downregulation of CXCR4 but fail to potentiate AraC/Idarubicin activity in preclinical models of non del5q/...

por Lopez-Millan, Belen, Diaz de la Guardia, Rafael, Roca-Ho, Heleia, Anguita, Eduardo, Islam, Abul B. M. M. K., Romero-Moya, Damia, Prieto, Cristina, Gutierrez-Agüera, Francisco, Bejarano-Garcia, Jose Antonio, Perez-Simon, Jose Antonio, Costales, Paula, Rovira, Montse, Marín, Pedro, Menendez, Silvia, Iglesias, Mar, Fuster, Jose Luis, Urbano-Ispizua, Alvaro, Anjos-Afonso, Fernando, Bueno, Clara, Menendez, Pablo
Publicado 2018

Comparison of outcomes for HLA-matched sibling and haplo-identical donors in Myelodysplastic syndromes: report from the chronic malignancies working party of EBMT

por Raj, Kavita, Eikema, Dirk-Jan, Sheth, Vipul, Koster, Linda, de Wreede, Liesbeth C., Blaise, Didier, Di Grazia, Carmela, Koc, Yener, Potter, Victoria, Chevallier, Patrice, Lopez- Corral, Lucia, Wu, Depei, Mielke, Stephan, Maertens, Johan, Meijer, Ellen, Huynh, Anne, Passweg, Jakob, Luft, Thomas, Pérez-Simón, Jose Antonio, Ciceri, Fabio, Piekarska, Agnieszka, Hayri Ozsan, G., Kröger, Nicolaus, Robin, Marie, Yakoub-Agha, Ibrahim
Publicado 2022