A FRET-based assay for characterization of alternative splicing events using peptide nucleic acid fluorescence in situ hybridization

por Blanco, Ana M., Rausell, Laura, Aguado, Begoña, Perez-Alonso, Manuel, Artero, Rubén
Publicado 2009

Expanded CCUG repeat RNA expression in Drosophila heart and muscle trigger Myotonic Dystrophy type 1-like phenotypes and activate autophagocytosis genes

por Cerro-Herreros, Estefania, Chakraborty, Mouli, Pérez-Alonso, Manuel, Artero, Rubén, Llamusí, Beatriz
Publicado 2017

Quantitative magnetic resonance imaging assessment of muscle composition in myotonic dystrophy mice

por Bargiela, Ariadna, Ten-Esteve, Amadeo, Martí-Bonmatí, Luis, Sevilla, Teresa, Perez Alonso, Manuel, Artero, Ruben
Publicado 2023

Therapeutic Potential of AntagomiR-23b for Treating Myotonic Dystrophy

por Cerro-Herreros, Estefanía, González-Martínez, Irene, Moreno-Cervera, Nerea, Overby, Sarah, Pérez-Alonso, Manuel, Llamusí, Beatriz, Artero, Rubén
Publicado 2020

miR-23b and miR-218 silencing increase Muscleblind-like expression and alleviate myotonic dystrophy phenotypes in mammalian models

por Cerro-Herreros, Estefania, Sabater-Arcis, Maria, Fernandez-Costa, Juan M., Moreno, Nerea, Perez-Alonso, Manuel, Llamusi, Beatriz, Artero, Ruben
Publicado 2018

Defined d-hexapeptides bind CUG repeats and rescue phenotypes of myotonic dystrophy myotubes in a Drosophila model of the disease

por Rapisarda, Anna, Bargiela, Ariadna, Llamusi, Beatriz, Pont, Isabel, Estrada-Tejedor, Roger, Garcia-España, Enrique, Artero, Ruben, Perez-Alonso, Manuel
Publicado 2021

Natural Compound Boldine Lessens Myotonic Dystrophy Type 1 Phenotypes in DM1 Drosophila Models, Patient-Derived Cell Lines, and HSA(LR) Mice

por Álvarez-Abril, Mari Carmen, García-Alcover, Irma, Colonques-Bellmunt, Jordi, Garijo, Raquel, Pérez-Alonso, Manuel, Artero, Rubén, López-Castel, Arturo
Publicado 2023

Pentamidine rescues contractility and rhythmicity in a Drosophila model of myotonic dystrophy heart dysfunction

por Chakraborty, Mouli, Selma-Soriano, Estela, Magny, Emile, Couso, Juan Pablo, Pérez-Alonso, Manuel, Charlet-Berguerand, Nicolas, Artero, Ruben, Llamusi, Beatriz
Publicado 2015

Development of a Drosophila melanogaster spliceosensor system for in vivo high-throughput screening in myotonic dystrophy type 1

por García-Alcover, Irma, Colonques-Bellmunt, Jordi, Garijo, Raquel, Tormo, José R., Artero, Rubén, Álvarez-Abril, Mari Carmen, López Castel, Arturo, Pérez-Alonso, Manuel
Publicado 2014

Six Serum miRNAs Fail to Validate as Myotonic Dystrophy Type 1 Biomarkers

por Fernandez-Costa, Juan M., Llamusi, Beatriz, Bargiela, Ariadna, Zulaica, Miren, Alvarez-Abril, M. Carmen, Perez-Alonso, Manuel, Lopez de Munain, Adolfo, Lopez-Castel, Arturo, Artero, Ruben
Publicado 2016

In silico discovery of substituted pyrido[2,3-d]pyrimidines and pentamidine-like compounds with biological activity in myotonic dystrophy models

por González, Àlex L., Konieczny, Piotr, Llamusi, Beatriz, Delgado-Pinar, Estefanía, Borrell, José I., Teixidó, Jordi, García-España, Enrique, Pérez-Alonso, Manuel, Estrada-Tejedor, Roger, Artero, Rubén
Publicado 2017

Design of novel small molecule base-pair recognizers of toxic CUG RNA transcripts characteristics of DM1

por Ondono, Raul, Lirio, Ángel, Elvira, Carlos, Álvarez-Marimon, Elena, Provenzano, Claudia, Cardinali, Beatrice, Pérez-Alonso, Manuel, Perálvarez-Marín, Alex, Borrell, José I., Falcone, Germana, Estrada-Tejedor, Roger
Publicado 2020

Proof of concept of peptide-linked blockmiR-induced MBNL functional rescue in myotonic dystrophy type 1 mouse model

por Overby, Sarah J., Cerro-Herreros, Estefanía, González-Martínez, Irene, Varela, Miguel A., Seoane-Miraz, David, Jad, Yahya, Raz, Richard, Møller, Thorleif, Pérez-Alonso, Manuel, Wood, Matthew J., Llamusí, Beatriz, Artero, Rubén
Publicado 2022

BlockmiR AONs as Site-Specific Therapeutic MBNL Modulation in Myotonic Dystrophy 2D and 3D Muscle Cells and HSA(LR) Mice

por Overby, Sarah J., Cerro-Herreros, Estefanía, Espinosa-Espinosa, Jorge, González-Martínez, Irene, Moreno, Nerea, Fernández-Costa, Juan M., Balaguer-Trias, Jordina, Ramón-Azcón, Javier, Pérez-Alonso, Manuel, Møller, Thorleif, Llamusí, Beatriz, Artero, Rubén
Publicado 2023

Preclinical characterization of antagomiR-218 as a potential treatment for myotonic dystrophy

por Cerro-Herreros, Estefanía, González-Martínez, Irene, Moreno, Nerea, Espinosa-Espinosa, Jorge, Fernández-Costa, Juan M., Colom-Rodrigo, Anna, Overby, Sarah J., Seoane-Miraz, David, Poyatos-García, Javier, Vilchez, Juan J., López de Munain, Adolfo, Varela, Miguel A., Wood, Matthew J., Pérez-Alonso, Manuel, Llamusí, Beatriz, Artero, Rubén
Publicado 2021