The Traf2DNxBCL2-tg Mouse Model of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Recapitulates the Biased IGHV Gene Usage, Stereotypy, and Antigen-Specific HCDR3 Selectio...

por Perez-Chacon, Gema, Zapata, Juan M.
Publicado 2021

Editorial: Mouse Models of B Cell Malignancies

por Perez-Chacon, Gema, Vincent-Fabert, Christelle, Zapata, Juan M.
Publicado 2021

Dysregulated TRAF3 and BCL2 Expression Promotes Multiple Classes of Mature Non-hodgkin B Cell Lymphoma in Mice

por Perez-Chacon, Gema, Adrados, Magdalena, Vallejo-Cremades, Maria T., Lefebvre, Sophie, Reed, John C., Zapata, Juan M.
Publicado 2019

CD137 (4-1BB) Signalosome: Complexity Is a Matter of TRAFs

por Zapata, Juan M., Perez-Chacon, Gema, Carr-Baena, Pablo, Martinez-Forero, Ivan, Azpilikueta, Arantza, Otano, Itziar, Melero, Ignacio
Publicado 2018

Fludarabine Inhibits K(V)1.3 Currents in Human B Lymphocytes

por de la Cruz, Alicia, Vera-Zambrano, Alba, Peraza, Diego A., Valenzuela, Carmen, Zapata, Juan M., Perez-Chacon, Gema, Gonzalez, Teresa
Publicado 2017

From Ugi Multicomponent Reaction to Linkers for Bioconjugation

por Ramos-Tomillero, Iván, Pérez-Chacon, Gema, Somovilla-Crespo, Beatriz, Sánchez-Madrid, Francisco, Cuevas, Carmen, Zapata, Juan Manuel, Domínguez, Juan Manuel, Rodríguez, Hortensia, Albericio, Fernando
Publicado 2020

Synergistic Activity of Deguelin and Fludarabine in Cells from Chronic Lymphocytic Leukemia Patients and in the New Zealand Black Murine Model

por Rebolleda, Nerea, Losada-Fernandez, Ignacio, Perez-Chacon, Gema, Castejon, Raquel, Rosado, Silvia, Morado, Marta, Vallejo-Cremades, Maria Teresa, Martinez, Andrea, Vargas-Nuñez, Juan A., Perez-Aciego, Paloma
Publicado 2016

Association of the microsatellite in the 3' untranslated region of the CD154 gene with rheumatoid arthritis in females from a Spanish cohort: a case-control study

por Martin-Donaire, Trinidad, Losada-Fernandez, Ignacio, Perez-Chacon, Gema, Rua-Figueroa, Iñigo, Erausquin, Celia, Naranjo-Hernandez, Antonio, Rosado, Silvia, Sanchez, Florentino, Garcia-Saavedra, Ayoze, Citores, Maria Jesus, Vargas, Juan A, Perez-Aciego, Paloma
Publicado 2007

CD13 as a new tumor target for antibody-drug conjugates: validation with the conjugate MI130110

por Domínguez, Juan Manuel, Pérez-Chacón, Gema, Guillén, María José, Muñoz-Alonso, María José, Somovilla-Crespo, Beatriz, Cibrián, Danay, Acosta-Iborra, Bárbara, Adrados, Magdalena, Muñoz-Calleja, Cecilia, Cuevas, Carmen, Sánchez-Madrid, Francisco, Avilés, Pablo, Zapata, Juan M.
Publicado 2020

Case Report: An EGFR-Targeted 4-1BB-agonistic Trimerbody Does Not Induce Hepatotoxicity in Transgenic Mice With Liver Expression of Human EGFR

por Compte, Marta, Harwood, Seandean L., Martínez-Torrecuadrada, Jorge, Perez-Chacon, Gema, González-García, Patricia, Tapia-Galisteo, Antonio, Van Bergen en Henegouwen, Paul M. P., Sánchez, Aránzazu, Fabregat, Isabel, Sanz, Laura, Zapata, Juan M., Alvarez-Vallina, Luis
Publicado 2021

Anti-CCR7 therapy exerts a potent anti-tumor activity in a xenograft model of human mantle cell lymphoma

por Somovilla-Crespo, Beatriz, Alfonso-Pérez, Manuel, Cuesta-Mateos, Carlos, Carballo-de Dios, Cristina, Beltrán, Amada E, Terrón, Fernando, Pérez-Villar, Juan J, Gamallo-Amat, Carlos, Pérez-Chacón, Gema, Fernández-Ruiz, Elena, Zapata, Juan M, Muñoz-Calleja, Cecilia
Publicado 2013

A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity

por Compte, Marta, Harwood, Seandean Lykke, Muñoz, Ines G., Navarro, Rocio, Zonca, Manuela, Perez-Chacon, Gema, Erce-Llamazares, Ainhoa, Merino, Nekane, Tapia-Galisteo, Antonio, Cuesta, Angel M., Mikkelsen, Kasper, Caleiras, Eduardo, Nuñez-Prado, Natalia, Aznar, M. Angela, Lykkemark, Simon, Martínez-Torrecuadrada, Jorge, Melero, Ignacio, Blanco, Francisco J., Bernardino de la Serna, Jorge, Zapata, Juan M., Sanz, Laura, Alvarez-Vallina, Luis
Publicado 2018

RANK is a poor prognosis marker and a therapeutic target in ER‐negative postmenopausal breast cancer

por Ciscar, Marina, Trinidad, Eva M, Perez‐Chacon, Gema, Alsaleem, Mansour, Jimenez, Maria, Jimenez‐Santos, Maria J, Perez‐Montoyo, Hector, Sanz‐Moreno, Adrian, Vethencourt, Andrea, Toss, Michael, Petit, Anna, Soler‐Monso, Maria T, Lopez, Victor, Gomez‐Miragaya, Jorge, Gomez‐Aleza, Clara, Dobrolecki, Lacey E, Lewis, Michael T, Bruna, Alejandra, Mouron, Silvana, Quintela‐Fandino, Miguel, Al‐Shahrour, Fatima, Martinez‐Aranda, Antonio, Sierra, Angels, Green, Andrew R, Rakha, Emad, Gonzalez‐Suarez, Eva
Publicado 2023