Molecular reshaping of phage-displayed Interleukin-2 at beta chain receptor interface to obtain potent super-agonists with improved developability profiles

por Rojas, Gertrudis, Relova-Hernández, Ernesto, Pérez-Riverón, Annia, Castro-Martínez, Camila, Diaz-Bravo, Osmany, Infante, Yanelys Cabrera, Gómez, Tania, Solozábal, Joaquín, DíazBravo, Ana Beatriz, Schubert, Maren, Becker, Marlies, Pérez-Massón, Beatriz, Pérez-Martínez, Dayana, Alvarez-Arzola, Rydell, Guirola, Osmany, Chinea, Glay, Graca, Luis, Dübel, Stefan, León, Kalet, Carmenate, Tania
Publicado 2023

In-solution buffer-free digestion allows full-sequence coverage and complete characterization of post-translational modifications of the receptor-binding domain of SARS-CoV-2 in a...

por Espinosa, Luis Ariel, Ramos, Yassel, Andújar, Ivan, Torres, Enso Onill, Cabrera, Gleysin, Martín, Alejandro, Roche, Diamilé, Chinea, Glay, Becquet, Mónica, González, Isabel, Canaán-Haden, Camila, Nelson, Elías, Rojas, Gertrudis, Pérez-Massón, Beatriz, Pérez-Martínez, Dayana, Boggiano, Tamy, Palacio, Julio, Lozada Chang, Sum Lai, Hernández, Lourdes, de la Luz Hernández, Kathya Rashida, Markku, Saloheimo, Vitikainen, Marika, Valdés-Balbín, Yury, Santana-Medero, Darielys, Rivera, Daniel G., Vérez-Bencomo, Vicente, Emalfarb, Mark, Tchelet, Ronen, Guillén, Gerardo, Limonta, Miladys, Pimentel, Eulogio, Ayala, Marta, Besada, Vladimir, González, Luis Javier
Publicado 2021

Development of a scalable single process for producing SARS-CoV-2 RBD monomer and dimer vaccine antigens

por Boggiano-Ayo, Tammy, Palacios-Oliva, Julio, Lozada-Chang, Sumlai, Relova-Hernandez, Ernesto, Gomez-Perez, Jose, Oliva, Gonzalo, Hernandez, Lourdes, Bueno-Soler, Alexi, Montes de Oca, Daidee, Mora, Osvaldo, Machado-Santisteban, Roberto, Perez-Martinez, Dayana, Perez-Masson, Beatriz, Cabrera Infante, Yanelys, Calzadilla-Rosado, Lisandra, Ramirez, Yaima, Aymed-Garcia, Judey, Ruiz-Ramirez, Ingrid, Romero, Yamile, Gomez, Tania, Espinosa, Luis A., Gonzalez, Luis Javier, Cabrales, Annia, Guirola, Osmany, de la Luz, Kathya Rashida, Pi-Estopiñan, Franciscary, Sanchez-Ramirez, Belinda, Garcia-Rivera, Dagmar, Valdes-Balbin, Yuri, Rojas, Gertrudis, Leon-Monzon, Kalet, Ojito-Magaz, Eduardo, Hardy, Eugenio
Publicado 2023

A COVID-19 vaccine candidate composed of the SARS-CoV-2 RBD dimer and Neisseria meningitidis outer membrane vesicles

por Santana-Mederos, Darielys, Perez-Nicado, Rocmira, Climent, Yanet, Rodriguez, Laura, Ramirez, Belinda Sanchez, Perez-Rodriguez, Sonia, Rodriguez, Meybi, Labrada, Claudia, Hernandez, Tays, Diaz, Marianniz, Orosa, Ivette, Ramirez, Ubel, Oliva, Reynaldo, Garrido, Raine, Cardoso, Felix, Landys, Mario, Martinez, Roselyn, Gonzalez, Humberto, Hernandez, Tamara, Ochoa-Azze, Rolando, Perez, Jose L., Enriquez, Juliet, Gonzalez, Nibaldo, Infante, Yenicet, Espinosa, Luis A., Ramos, Yassel, González, Luis Javier, Valenzuela, Carmen, Casadesus, Ana Victoria, Fernandez, Briandy, Rojas, Gertrudis, Pérez-Massón, Beatriz, Tundidor, Yaima, Bermudez, Ernesto, Plasencia, Claudia A., Boggiano, Tammy, Ojito, Eduardo, Chiodo, Fabrizio, Fernandez, Sonsire, Paquet, Françoise, Fang, Cheng, Chen, Guang-Wu, Rivera, Daniel G., Valdes-Balbin, Yury, Garcia-Rivera, Dagmar, Verez Bencomo, Vicente
Publicado 2021

Safety and immunogenicity of anti-SARS CoV-2 vaccine SOBERANA 02 in homologous or heterologous scheme: Open label phase I and phase IIa clinical trials

por Eugenia-Toledo-Romaní, María, Verdecia-Sánchez, Leslyhana, Rodríguez-González, Meiby, Rodríguez-Noda, Laura, Valenzuela-Silva, Carmen, Paredes-Moreno, Beatriz, Sánchez-Ramírez, Belinda, Pérez-Nicado, Rocmira, González-Mugica, Raul, Hernández-García, Tays, Bergado-Baez, Gretchen, Pi-Estopiñán, Franciscary, Cruz-Sui, Otto, Fraga-Quintero, Anitza, García-Montero, Majela, Palenzuela-Díaz, Ariel, Baró-Román, Gerardo, Mendoza-Hernández, Ivis, Fernandez-Castillo, Sonsire, Climent-Ruiz, Yanet, Santana-Mederos, Darielys, Ramírez Gonzalez, Ubel, García-Vega, Yanelda, Pérez-Massón, Beatriz, Guang-Wu-Chen, Boggiano-Ayo, Tammy, Ojito-Magaz, Eduardo, Rivera, Daniel G., Valdés-Balbín, Yury, García-Rivera, Dagmar, Vérez-Bencomo, Vicente, Gómez-Maceo, Yanet, Reyes-Matienzo, Radamet, Manuel Coviella-Artime, José, Morffi-Cinta, Irania, Martínez-Pérez, Marisel, Castillo-Quintana, Ismavy, Garcés-Hechavarría, Aniurka, Valera-Fernández, Rodrigo, Martínez-Bedoya, Dayle, Garrido-Arteaga, Raine, Cardoso-SanJorge, Félix, Quintero Moreno, Lauren, Ontivero-Pino, Ivis, Teresa Pérez-Guevara, María, Morales-García, Marilin, Noa-Romero, Enrique, Orosa-Vázquez, Ivette, Díaz-Hernández, Marianniz, Rojas, Gertrudis, Tundidor, Yaima, García-López, Elena, Muñoz-Morejon, Yaima, Galano-Frutos, Evelyn, Rodríguez-Alvarez, Julián, Arteaga, Amaylid, Medina Nápoles, Maite, Espi Ávila, Jennifer, Fontanies Fernández, Marcos
Publicado 2022