Pulmonary Deposition and Elimination of Liposomal Amikacin for Inhalation and Effect on Macrophage Function after Administration in Rats

por Malinin, Vladimir, Neville, Mary, Eagle, Gina, Gupta, Renu, Perkins, Walter R.
Publicado 2016

Effect of Inhalation Profile on Delivery of Treprostinil Palmitil Inhalation Powder

por Gauani, Helena, Baker, Thomas, Li, Zhili, Malinin, Vladimir S., Perkins, Walter R., Sullivan, Eugene J., Cipolla, David
Publicado 2023

Amikacin Liposome Inhalation Suspension (ALIS) Penetrates Non-tuberculous Mycobacterial Biofilms and Enhances Amikacin Uptake Into Macrophages

por Zhang, Jimin, Leifer, Franziska, Rose, Sasha, Chun, Dung Yu, Thaisz, Jill, Herr, Tracey, Nashed, Mary, Joseph, Jayanthi, Perkins, Walter R., DiPetrillo, Keith
Publicado 2018

Brensocatib, an oral, reversible inhibitor of dipeptidyl peptidase 1, mitigates interferon-α-accelerated lupus nephritis in mice

por Chen, Kuan-Ju, Zhang, Jimin, LaSala, Daniel, Basso, Jessica, Chun, Donald, Zhou, Yuchen, McDonald, Patrick P., Perkins, Walter R., Cipolla, David C.
Publicado 2023

Brensocatib (an oral, reversible inhibitor of dipeptidyl peptidase-1) attenuates disease progression in two animal models of rheumatoid arthritis

por McDonald, Patrick P., Leifer, Franziska Graf, Basso, Jessica, Lasala, Dan, Li, Dedong, Chen, Kuan-Ju, Zhang, Jimin, Perkins, Walter R., Cipolla, David C.
Publicado 2023

Dipeptidyl peptidase-1 inhibition with brensocatib reduces the activity of all major neutrophil serine proteases in patients with bronchiectasis: results from the WILLOW trial

por Cipolla, David, Zhang, Jimin, Korkmaz, Brice, Chalmers, James D., Basso, Jessica, Lasala, Daniel, Fernandez, Carlos, Teper, Ariel, Mange, Kevin C., Perkins, Walter R., Sullivan, Eugene J.
Publicado 2023

Preclinical Investigation of a Lipoglycopeptide Dry Powder Inhalation Therapy for the Treatment of Pulmonary MRSA Infection

por Konicek, Donna M., Plaunt, Adam J., Gharse, Sachin, Rose, Sasha J., Dorfman, Arielle, Sabnis, Amruta, Baker, Thomas, Gauani, Helena, Chun, Donald, Li, Zhili, Perkins, Walter R., Cipolla, David, Malinin, Vladimir S.
Publicado 2023

Development and Characterization of Treprostinil Palmitil Inhalation Aerosol for the Investigational Treatment of Pulmonary Arterial Hypertension

por Plaunt, Adam J., Islam, Sadikul, Macaluso, Tony, Gauani, Helena, Baker, Thomas, Chun, Donald, Viramontes, Veronica, Chang, Christina, Corboz, Michel R., Chapman, Richard W., Li, Zhili, Cipolla, David C., Perkins, Walter R., Malinin, Vladimir S.
Publicado 2021

Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcus aureus Infections

por Plaunt, Adam J., Rose, Sasha J., Kang, Jeong Yeon, Chen, Kuan-Ju, LaSala, Daniel, Heckler, Ryan P., Dorfman, Arielle, Smith, Barrett T., Chun, Donald, Viramontes, Veronica, Macaluso, Antonio, Li, Zhili, Zhou, Yuchen, Mark, Lilly, Basso, Jessica, Leifer, Franziska G., Corboz, Michel R., Chapman, Richard W., Cipolla, David, Perkins, Walter R., Malinin, Vladimir S., Konicek, Donna M.
Publicado 2021