A high yield optimized method for the production of acylated ACPs enabling the analysis of enzymes involved in P. falciparum fatty acid biosynthesis

por Lauciello, Leonardo, Lack, Gabriela, Scapozza, Leonardo, Perozzo, Remo
Publicado 2016

Crystal Structures of T. b. rhodesiense Adenosine Kinase Complexed with Inhibitor and Activator: Implications for Catalysis and Hyperactivation

por Kuettel, Sabine, Greenwald, Jason, Kostrewa, Dirk, Ahmed, Shaheen, Scapozza, Leonardo, Perozzo, Remo
Publicado 2011

Adenosine Kinase of T. b. rhodesiense Identified as the Putative Target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine Using Chemical Proteomics

por Kuettel, Sabine, Mosimann, Marc, Mäser, Pascal, Kaiser, Marcel, Brun, Reto, Scapozza, Leonardo, Perozzo, Remo
Publicado 2009

Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation

por Conus, Sébastien, Perozzo, Remo, Reinheckel, Thomas, Peters, Christoph, Scapozza, Leonardo, Yousefi, Shida, Simon, Hans-Uwe
Publicado 2008

From compound to target: chemical proteomics and in silico screening identify Hsp90 and CDPK2 as putative targets in Plasmodium falciparum

por Lauciello, Leonardo, Ahmed, Shaheen, Derrer, Bianca, Kappes, Barbara, Wang, Tai, Seebacher, Werner, Scapozza, Leonardo, Perozzo, Remo
Publicado 2012

Platelet Transforming Growth Factor-β1 Induces Liver Sinusoidal Endothelial Cells to Secrete Interleukin-6

por Balaphas, Alexandre, Meyer, Jeremy, Perozzo, Remo, Zeisser-Labouebe, Magali, Berndt, Sarah, Turzi, Antoine, Fontana, Pierre, Scapozza, Leonardo, Gonelle-Gispert, Carmen, Bühler, Leo H.
Publicado 2020

Naphthoquinone Derivatives Exert Their Antitrypanosomal Activity via a Multi-Target Mechanism

por Pieretti, Simone, Haanstra, Jurgen R., Mazet, Muriel, Perozzo, Remo, Bergamini, Christian, Prati, Federica, Fato, Romana, Lenaz, Giorgio, Capranico, Giovanni, Brun, Reto, Bakker, Barbara M., Michels, Paul A. M., Scapozza, Leonardo, Bolognesi, Maria Laura, Cavalli, Andrea
Publicado 2013

Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes

por Garcia-Lopez, Amparo, Tessaro, Francesca, Jonker, Hendrik R. A., Wacker, Anna, Richter, Christian, Comte, Arnaud, Berntenis, Nikolaos, Schmucki, Roland, Hatje, Klas, Petermann, Olivier, Chiriano, Gianpaolo, Perozzo, Remo, Sciarra, Daniel, Konieczny, Piotr, Faustino, Ignacio, Fournet, Guy, Orozco, Modesto, Artero, Ruben, Metzger, Friedrich, Ebeling, Martin, Goekjian, Peter, Joseph, Benoît, Schwalbe, Harald, Scapozza, Leonardo
Publicado 2018