Modeling and Targeting Neuroglial Interactions with Human Pluripotent Stem Cell Models

por Bigarreau, Julie, Rouach, Nathalie, Perrier, Anselme L., Mouthon, Franck, Charvériat, Mathieu
Publicado 2022

Propagation of α-Synuclein Strains within Human Reconstructed Neuronal Network

por Gribaudo, Simona, Tixador, Philippe, Bousset, Luc, Fenyi, Alexis, Lino, Patricia, Melki, Ronald, Peyrin, Jean-Michel, Perrier, Anselme L.
Publicado 2019

Dominant-Negative Effects of Adult-Onset Huntingtin Mutations Alter the Division of Human Embryonic Stem Cells-Derived Neural Cells

por Lopes, Carla, Aubert, Sophie, Bourgois-Rocha, Fany, Barnat, Monia, Rego, Ana Cristina, Déglon, Nicole, Perrier, Anselme L., Humbert, Sandrine
Publicado 2016

Differentiation of nonhuman primate pluripotent stem cells into functional keratinocytes

por Domingues, Sophie, Masson, Yolande, Marteyn, Aurore, Allouche, Jennifer, Perrier, Anselme L., Peschanski, Marc, Martinat, Cecile, Baldeschi, Christine, Lemaître, Gilles
Publicado 2017

CTIP2-Regulated Reduction in PKA-Dependent DARPP32 Phosphorylation in Human Medium Spiny Neurons: Implications for Huntington Disease

por Fjodorova, Marija, Louessard, Morgane, Li, Zongze, De La Fuente, Daniel C., Dyke, Emma, Brooks, Simon P., Perrier, Anselme L., Li, Meng
Publicado 2019

Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson’s Disease

por Grealish, Shane, Diguet, Elsa, Kirkeby, Agnete, Mattsson, Bengt, Heuer, Andreas, Bramoulle, Yann, Van Camp, Nadja, Perrier, Anselme L., Hantraye, Philippe, Björklund, Anders, Parmar, Malin
Publicado 2014

Increasing brain palmitoylation rescues behavior and neuropathology in Huntington disease mice

por Virlogeux, Amandine, Scaramuzzino, Chiara, Lenoir, Sophie, Carpentier, Rémi, Louessard, Morgane, Genoux, Aurélie, Lino, Patricia, Hinckelmann, Maria-Victoria, Perrier, Anselme L., Humbert, Sandrine, Saudou, Frédéric
Publicado 2021

MHC matching fails to prevent long-term rejection of iPSC-derived neurons in non-human primates

por Aron Badin, Romina, Bugi, Aurore, Williams, Susannah, Vadori, Marta, Michael, Marie, Jan, Caroline, Nassi, Alberto, Lecourtois, Sophie, Blancher, Antoine, Cozzi, Emanuele, Hantraye, Philippe, Perrier, Anselme L.
Publicado 2019

Quantification of Total and Mutant Huntingtin Protein Levels in Biospecimens Using a Novel alphaLISA Assay

por Baldo, Barbara, Sajjad, Muhammad Umar, Cheong, Rachel Y., Bigarreau, Julie, Vijayvargia, Ravi, McLean, Catriona, Perrier, Anselme L., Seong, Ihn Sik, Halliday, Glenda, Petersén, Åsa, Kirik, Deniz
Publicado 2018

Preclinical Evaluation of a Lentiviral Vector for Huntingtin Silencing

por Cambon, Karine, Zimmer, Virginie, Martineau, Sylvain, Gaillard, Marie-Claude, Jarrige, Margot, Bugi, Aurore, Miniarikova, Jana, Rey, Maria, Hassig, Raymonde, Dufour, Noelle, Auregan, Gwenaelle, Hantraye, Philippe, Perrier, Anselme L., Déglon, Nicole
Publicado 2017

Human Induced Pluripotent Stem Cell-Derived Astrocytes Are Differentially Activated by Multiple Sclerosis-Associated Cytokines

por Perriot, Sylvain, Mathias, Amandine, Perriard, Guillaume, Canales, Mathieu, Jonkmans, Nils, Merienne, Nicolas, Meunier, Cécile, El Kassar, Lina, Perrier, Anselme L., Laplaud, David-Axel, Schluep, Myriam, Déglon, Nicole, Du Pasquier, Renaud
Publicado 2018

Allele-Specific Silencing of Mutant Huntingtin in Rodent Brain and Human Stem Cells

por Drouet, Valérie, Ruiz, Marta, Zala, Diana, Feyeux, Maxime, Auregan, Gwennaëlle, Cambon, Karine, Troquier, Laetitia, Carpentier, Johann, Aubert, Sophie, Merienne, Nicolas, Bourgois-Rocha, Fany, Hassig, Raymonde, Rey, Maria, Dufour, Noëlle, Saudou, Frédéric, Perrier, Anselme L., Hantraye, Philippe, Déglon, Nicole
Publicado 2014

Translating cell therapies for neurodegenerative diseases: Huntington’s disease as a model disorder

por Rosser, Anne E., Busse, Monica E., Gray, William P., Badin, Romina Aron, Perrier, Anselme L., Wheelock, Vicki, Cozzi, Emanuele, Martin, Unai Perpiña, Salado-Manzano, Cristina, Mills, Laura J., Drew, Cheney, Goldman, Steven A., Canals, Josep M., Thompson, Leslie M.
Publicado 2022

The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin

por Galvan, Laurie, Francelle, Laetitia, Gaillard, Marie-Claude, de Longprez, Lucie, Carrillo-de Sauvage, Maria-Angeles, Liot, Géraldine, Cambon, Karine, Stimmer, Lev, Luccantoni, Sophie, Flament, Julien, Valette, Julien, de Chaldée, Michel, Auregan, Gwenaelle, Guillermier, Martine, Joséphine, Charlène, Petit, Fanny, Jan, Caroline, Jarrige, Margot, Dufour, Noëlle, Bonvento, Gilles, Humbert, Sandrine, Saudou, Frédéric, Hantraye, Philippe, Merienne, Karine, Bemelmans, Alexis-Pierre, Perrier, Anselme L, Déglon, Nicole, Brouillet, Emmanuel
Publicado 2018