Prevention and Reversal of Antibody Responses Against Factor IX in Gene Therapy for Hemophilia B

por Nayak, Sushrusha, Sarkar, Debalina, Perrin, George Q., Moghimi, Babak, Hoffman, Brad E., Zhou, Shangzhen, Byrne, Barry J., Herzog, Roland W.
Publicado 2011

Dynamics of antigen presentation to transgene product-specific CD4(+) T cells and of Treg induction upon hepatic AAV gene transfer

por Perrin, George Q, Zolotukhin, Irene, Sherman, Alexandra, Biswas, Moanaro, de Jong, Ype P, Terhorst, Cox, Davidoff, Andrew M, Herzog, Roland W
Publicado 2016

Effective gene therapy for haemophilic mice with pathogenic factor IX antibodies

por Markusic, David M, Hoffman, Brad E, Perrin, George Q, Nayak, Sushrusha, Wang, Xiaomei, LoDuca, Paul A, High, Katherine A, Herzog, Roland W
Publicado 2013

Ex vivo expanded autologous polyclonal regulatory T cells suppress inhibitor formation in hemophilia

por Sarkar, Debalina, Biswas, Moanaro, Liao, Gongxian, Seay, Howard R, Perrin, George Q, Markusic, David M, Hoffman, Brad E, Brusko, Todd M, Terhorst, Cox, Herzog, Roland W
Publicado 2014

Oral Tolerance Induction in Hemophilia B Dogs Fed with Transplastomic Lettuce

por Herzog, Roland W., Nichols, Timothy C., Su, Jin, Zhang, Bei, Sherman, Alexandra, Merricks, Elizabeth P., Raymer, Robin, Perrin, George Q., Häger, Mattias, Wiinberg, Bo, Daniell, Henry
Publicado 2017

Factor VIII trafficking to CD4(+) T cells shapes its immunogenicity and requires several types of antigen-presenting cells

por Kaczmarek, Radoslaw, Piñeros, Annie R., Patterson, Paige E., Bertolini, Thais B., Perrin, George Q., Sherman, Alexandra, Born, Jameson, Arisa, Sreevani, Arvin, Matthew C., Kamocka, Malgorzata M., Martinez, Michelle M., Dunn, Kenneth W., Quinn, Sean M., Morris, Johnathan J., Wilhelm, Amelia R., Kaisho, Tsuneyasu, Munoz-Melero, Maite, Biswas, Moanaro, Kaplan, Mark H., Linnemann, Amelia K., George, Lindsey A., Camire, Rodney M., Herzog, Roland W.
Publicado 2023