β‐cell replacement therapy for type 1 diabetes: closer and closer

por Jones, Peter M., Persaud, Shanta J.
Publicado 2022

Effects of miR-33 Deficiency on Metabolic and Cardiovascular Diseases: Implications for Therapeutic Intervention

por Ortega, Rebeca, Liu, Bo, Persaud, Shanta J.
Publicado 2023

Using single‐cell multi‐omics screening of human fetal pancreas to identify novel players in human beta cell development

por Olaniru, Oladapo E., Hook, Philippa, Persaud, Shanta J.
Publicado 2022

Alterations in mouse visceral adipose tissue mRNA expression of islet G‐protein‐coupled receptor ligands in obesity

por Ashik, Tanyel, Lee, Vivian, Atanes, Patricio, Persaud, Shanta J.
Publicado 2022

The CaMK4/CREB/IRS-2 Cascade Stimulates Proliferation and Inhibits Apoptosis of β-Cells

por Liu, Bo, Barbosa-Sampaio, Helena, Jones, Peter M., Persaud, Shanta J., Muller, Dany S.
Publicado 2012

Direct Stimulatory Effects of the CB(2) Ligand JTE 907 in Human and Mouse Islets

por Ruz-Maldonado, Inmaculada, Atanes, Patricio, Huang, Guo Cai, Liu, Bo, Persaud, Shanta J
Publicado 2021

The cannabinoid ligands SR141716A and AM251 enhance human and mouse islet function via GPR55-independent signalling

por Ruz-Maldonado, Inmaculada, Liu, Bo, Atanes, Patricio, Pingitore, Attilio, Huang, Guo Cai, Choudhary, Pratik, Persaud, Shanta J.
Publicado 2020

Imatinib prevents beta cell death in vitro but does not improve islet transplantation outcome

por King, Aileen J. F., Griffiths, Lisa A., Persaud, Shanta J., Jones, Peter M., Howell, Simon L., Welsh, Nils
Publicado 2016

The adhesion receptor GPR56 is activated by extracellular matrix collagen III to improve β-cell function

por Olaniru, Oladapo E., Pingitore, Attilio, Giera, Stefanie, Piao, Xianhua, Castañera González, Ramón, Jones, Peter M., Persaud, Shanta J.
Publicado 2018

Neuropeptide Neuromedin B does not alter body weight and glucose homeostasis nor does it act as an insulin-releasing peptide

por Cikes, Domagoj, Atanes, Patricio, Cronin, Shane J. F., Hagelkrüys, Astrid, Huang, Guo-Cai, Persaud, Shanta J., Penninger, Josef M.
Publicado 2022

The selective serotonin reuptake inhibitor fluoxetine has direct effects on beta cells, promoting insulin secretion and increasing beta‐cell mass

por Liu, Bo, Ruz‐Maldonado, Inmaculada, Toczyska, Klaudia, Olaniru, Oladapo E., Zariwala, Mohammed Gulrez, Hopkins, David, Zhao, Min, Persaud, Shanta J.
Publicado 2022

C3aR and C5aR1 act as key regulators of human and mouse β-cell function

por Atanes, Patricio, Ruz-Maldonado, Inmaculada, Pingitore, Attilio, Hawkes, Ross, Liu, Bo, Zhao, Min, Huang, Guo Cai, Persaud, Shanta J., Amisten, Stefan
Publicado 2017

Prolonged activation of human islet cannabinoid receptors in vitro induces adaptation but not dysfunction

por Vilches-Flores, Alonso, Franklin, Zara, Hauge-Evans, Astrid C., Liu, Bo, Huang, Guo C., Choudhary, Pratik, Jones, Peter M., Persaud, Shanta J.
Publicado 2016

A comparative analysis of human and mouse islet G-protein coupled receptor expression

por Amisten, Stefan, Atanes, Patricio, Hawkes, Ross, Ruz-Maldonado, Inmaculada, Liu, Bo, Parandeh, Fariborz, Zhao, Min, Huang, Guo Cai, Salehi, Albert, Persaud, Shanta J.
Publicado 2017

APT070 (mirococept), a membrane‐localizing C3 convertase inhibitor, attenuates early human islet allograft damage in vitro and in vivo in a humanized mouse model

por Xiao, Fang, Ma, Liang, Zhao, Min, Smith, Richard A, Huang, Guocai, Jones, Peter M, Persaud, Shanta, Pingitore, Attilio, Dorling, Anthony, Lechler, Robert, Lombardi, Giovanna
Publicado 2016

Defining G protein-coupled receptor peptide ligand expressomes and signalomes in human and mouse islets

por Atanes, Patricio, Ruz-Maldonado, Inmaculada, Hawkes, Ross, Liu, Bo, Zhao, Min, Huang, Guo Cai, Al-Amily, Israa Mohammed, Salehi, Albert, Amisten, Stefan, Persaud, Shanta J.
Publicado 2018

Somatostatin Secreted by Islet δ-Cells Fulfills Multiple Roles as a Paracrine Regulator of Islet Function

por Hauge-Evans, Astrid C., King, Aileen J., Carmignac, Danielle, Richardson, Carolyn C., Robinson, Iain C.A.F., Low, Malcolm J., Christie, Michael R., Persaud, Shanta J., Jones, Peter M.
Publicado 2009

SNAP-tag-enabled super-resolution imaging reveals constitutive and agonist-dependent trafficking of GPR56 in pancreatic β-cells

por Olaniru, Oladapo E., Cheng, Jordan, Ast, Julia, Arvaniti, Anastasia, Atanes, Patricio, Huang, Guo C., King, Aileen J.F., Jones, Peter M., Broichhagen, Johannes, Hodson, David J., Persaud, Shanta J.
Publicado 2021

The cannabinoid ligand LH-21 reduces anxiety and improves glucose handling in diet-induced obese pre-diabetic mice

por Romero-Zerbo, Silvana Y., Ruz-Maldonado, Inmaculada, Espinosa-Jiménez, Vanesa, Rafacho, Alex, Gómez-Conde, Ana I., Sánchez-Salido, Lourdes, Cobo-Vuilleumier, Nadia, Gauthier, Benoit R., Tinahones, Francisco J., Persaud, Shanta J., Bermúdez-Silva, Francisco J.
Publicado 2017

Class II Phosphoinositide 3-Kinase Regulates Exocytosis of Insulin Granules in Pancreatic β Cells

por Dominguez, Veronica, Raimondi, Claudio, Somanath, Sangeeta, Bugliani, Marco, Loder, Merewyn K., Edling, Charlotte E., Divecha, Nullin, da Silva-Xavier, Gabriela, Marselli, Lorella, Persaud, Shanta J., Turner, Mark D., Rutter, Guy A., Marchetti, Piero, Falasca, Marco, Maffucci, Tania
Publicado 2011