Engineering Translation in Mammalian Cell Factories to Increase Protein Yield: The Unexpected Use of Long Non-Coding SINEUP RNAs

por Zucchelli, Silvia, Patrucco, Laura, Persichetti, Francesca, Gustincich, Stefano, Cotella, Diego
Publicado 2016

Analysis of LINE1 Retrotransposons in Huntington’s Disease

por Floreani, Lavinia, Ansaloni, Federico, Mangoni, Damiano, Agostoni, Elena, Sanges, Remo, Persichetti, Francesca, Gustincich, Stefano
Publicado 2022

An Air-well sparging minifermenter system for high-throughput protein production

por Deantonio, Cecilia, Sedini, Valentina, Cesaro, Patrizia, Quasso, Fabio, Cotella, Diego, Persichetti, Francesca, Santoro, Claudio, Sblattero, Daniele
Publicado 2014

Expression analysis of the long non-coding RNA antisense to Uchl1 (AS Uchl1) during dopaminergic cells' differentiation in vitro and in neurochemical models of Parkinson's disease

por Carrieri, Claudia, Forrest, Alistair R. R., Santoro, Claudio, Persichetti, Francesca, Carninci, Piero, Zucchelli, Silvia, Gustincich, Stefano
Publicado 2015

Transposable element activation promotes neurodegeneration in a Drosophila model of Huntington's disease

por Casale, Assunta Maria, Liguori, Francesco, Ansaloni, Federico, Cappucci, Ugo, Finaurini, Sara, Spirito, Giovanni, Persichetti, Francesca, Sanges, Remo, Gustincich, Stefano, Piacentini, Lucia
Publicado 2021

Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) Associates with Huntingtin Protein and Promotes Its Atypical Ubiquitination to Enhance Aggregate Formation

por Zucchelli, Silvia, Marcuzzi, Federica, Codrich, Marta, Agostoni, Elena, Vilotti, Sandra, Biagioli, Marta, Pinto, Milena, Carnemolla, Alisia, Santoro, Claudio, Gustincich, Stefano, Persichetti, Francesca
Publicado 2011

Neuronal haemoglobin induces loss of dopaminergic neurons in mouse Substantia nigra, cognitive deficits and cleavage of endogenous α-synuclein

por Santulli, Chiara, Bon, Carlotta, De Cecco, Elena, Codrich, Marta, Narkiewicz, Joanna, Parisse, Pietro, Perissinotto, Fabio, Santoro, Claudio, Persichetti, Francesca, Legname, Giuseppe, Espinoza, Stefano, Gustincich, Stefano
Publicado 2022

Specific transcriptional programs differentiate ICOS from CD28 costimulatory signaling in human Naïve CD4(+) T cells

por Gigliotti, Casimiro Luca, Boggio, Elena, Favero, Francesco, Incarnato, Danny, Santoro, Claudio, Oliviero, Salvatore, Rojo, Josè Maria, Zucchelli, Silvia, Persichetti, Francesca, Baldanzi, Gianluca, Dianzani, Umberto, Corà, Davide
Publicado 2022

SINEUPs are modular antisense long non-coding RNAs that increase synthesis of target proteins in cells

por Zucchelli, Silvia, Fasolo, Francesca, Russo, Roberta, Cimatti, Laura, Patrucco, Laura, Takahashi, Hazuki, Jones, Michael H., Santoro, Claudio, Sblattero, Daniele, Cotella, Diego, Persichetti, Francesca, Carninci, Piero, Gustincich, Stefano
Publicado 2015

The RNA-binding protein ILF3 binds to transposable element sequences in SINEUP lncRNAs

por Fasolo, Francesca, Patrucco, Laura, Volpe, Massimiliano, Bon, Carlotta, Peano, Clelia, Mignone, Flavio, Carninci, Piero, Persichetti, Francesca, Santoro, Claudio, Zucchelli, Silvia, Sblattero, Daniele, Sanges, Remo, Cotella, Diego, Gustincich, Stefano
Publicado 2019

Neuronal hemoglobin affects dopaminergic cells' response to stress

por Codrich, Marta, Bertuzzi, Maria, Russo, Roberta, Francescatto, Margherita, Espinoza, Stefano, Zentilin, Lorena, Giacca, Mauro, Cesselli, Daniela, Beltrami, Antonio Paolo, Ascenzi, Paolo, Zucchelli, Silvia, Persichetti, Francesca, Leanza, Giampiero, Gustincich, Stefano
Publicado 2017

SINEUPs: a novel toolbox for RNA therapeutics

por Espinoza, Stefano, Bon, Carlotta, Valentini, Paola, Pierattini, Bianca, Matey, Abraham Tettey, Damiani, Devid, Pulcrano, Salvatore, Sanges, Remo, Persichetti, Francesca, Takahashi, Hazuki, Carninci, Piero, Santoro, Claudio, Cotella, Diego, Gustincich, Stefano
Publicado 2021

SINEUP non-coding RNA activity depends on specific N6-methyladenosine nucleotides

por Pierattini, Bianca, D’Agostino, Sabrina, Bon, Carlotta, Peruzzo, Omar, Alendar, Andrej, Codino, Azzurra, Ros, Gloria, Persichetti, Francesca, Sanges, Remo, Carninci, Piero, Santoro, Claudio, Espinoza, Stefano, Valentini, Paola, Pandolfini, Luca, Gustincich, Stefano
Publicado 2023

Effects of Pin1 Loss in Hdh(Q111) Knock-in Mice

por Agostoni, Elena, Michelazzi, Silvia, Maurutto, Marta, Carnemolla, Alisia, Ciani, Yari, Vatta, Paolo, Roncaglia, Paola, Zucchelli, Silvia, Leanza, Giampiero, Mantovani, Fiamma, Gustincich, Stefano, Santoro, Claudio, Piazza, Silvano, Del Sal, Giannino, Persichetti, Francesca
Publicado 2016

Antisense Transcription in Loci Associated to Hereditary Neurodegenerative Diseases

por Zucchelli, Silvia, Fedele, Stefania, Vatta, Paolo, Calligaris, Raffaella, Heutink, Peter, Rizzu, Patrizia, Itoh, Masayoshi, Persichetti, Francesca, Santoro, Claudio, Kawaji, Hideya, Lassmann, Timo, Hayashizaki, Yoshihide, Carninci, Piero, Forrest, Alistair R. R., Gustincich, Stefano
Publicado 2019

LINE-1 regulates cortical development by acting as long non-coding RNAs

por Mangoni, Damiano, Simi, Alessandro, Lau, Pierre, Armaos, Alexandros, Ansaloni, Federico, Codino, Azzurra, Damiani, Devid, Floreani, Lavinia, Di Carlo, Valerio, Vozzi, Diego, Persichetti, Francesca, Santoro, Claudio, Pandolfini, Luca, Tartaglia, Gian Gaetano, Sanges, Remo, Gustincich, Stefano
Publicado 2023

SINEUP non-coding RNAs rescue defective frataxin expression and activity in a cellular model of Friedreich's Ataxia

por Bon, Carlotta, Luffarelli, Riccardo, Russo, Roberta, Fortuni, Silvia, Pierattini, Bianca, Santulli, Chiara, Fimiani, Cristina, Persichetti, Francesca, Cotella, Diego, Mallamaci, Antonello, Santoro, Claudio, Carninci, Piero, Espinoza, Stefano, Testi, Roberto, Zucchelli, Silvia, Condò, Ivano, Gustincich, Stefano
Publicado 2019

Mesencephalic dopaminergic neurons express a repertoire of olfactory receptors and respond to odorant-like molecules

por Grison, Alice, Zucchelli, Silvia, Urzì, Alice, Zamparo, Ilaria, Lazarevic, Dejan, Pascarella, Giovanni, Roncaglia, Paola, Giorgetti, Alejandro, Garcia-Esparcia, Paula, Vlachouli, Christina, Simone, Roberto, Persichetti, Francesca, Forrest, Alistair RR, Hayashizaki, Yoshihide, Carloni, Paolo, Ferrer, Isidro, Lodovichi, Claudia, Plessy, Charles, Carninci, Piero, Gustincich, Stefano
Publicado 2014