Three-dimensional missense tolerance ratio analysis

por Perszyk, Riley E., Kristensen, Anders S., Lyuboslavsky, Polina, Traynelis, Stephen F.
Publicado 2021

Adolescent cocaine exposure simplifies orbitofrontal cortical dendritic arbors

por DePoy, Lauren M., Perszyk, Riley E., Zimmermann, Kelsey S., Koleske, Anthony J., Gourley, Shannon L.
Publicado 2014

Structure, function, and allosteric modulation of NMDA receptors

por Hansen, Kasper B., Yi, Feng, Perszyk, Riley E., Furukawa, Hiro, Wollmuth, Lonnie P., Gibb, Alasdair J., Traynelis, Stephen F.
Publicado 2018

An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups

por Perszyk, Riley, Katzman, Brooke M, Kusumoto, Hirofumi, Kell, Steven A, Epplin, Matthew P, Tahirovic, Yesim A, Moore, Rhonda L, Menaldino, David, Burger, Pieter, Liotta, Dennis C, Traynelis, Stephen F
Publicado 2018

Classification of missense variants in the N-methyl-d-aspartate receptor GRIN gene family as gain- or loss-of-function

por Myers, Scott J, Yuan, Hongjie, Perszyk, Riley E, Zhang, Jing, Kim, Sukhan, Nocilla, Kelsey A, Allen, James P, Bain, Jennifer M, Lemke, Johannes R, Lal, Dennis, Benke, Timothy A, Traynelis, Stephen F
Publicado 2023

Biased modulators of NMDA receptors control channel opening and ion selectivity

por Perszyk, Riley E., Swanger, Sharon A., Shelley, Chris, Khatri, Alpa, Fernandez-Cuervo, Gabriela, Epplin, Matthew P., Zhang, Jing, Le, Phuong, Bülow, Pernille, Garnier-Amblard, Ethel, Gangireddy, Pavan Kumar Reddy, Bassell, Gary J., Yuan, Hongjie, Menaldino, David S., Liotta, Dennis C., Liebeskind, Lanny S., Traynelis, Stephen F.
Publicado 2020

Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels

por Hansen, Kasper B., Wollmuth, Lonnie P., Bowie, Derek, Furukawa, Hiro, Menniti, Frank S., Sobolevsky, Alexander I., Swanson, Geoffrey T., Swanger, Sharon A., Greger, Ingo H., Nakagawa, Terunaga, McBain, Chris J., Jayaraman, Vasanthi, Low, Chian-Ming, Dell’Acqua, Mark L., Diamond, Jeffrey S., Camp, Chad R., Perszyk, Riley E., Yuan, Hongjie, Traynelis, Stephen F.
Publicado 2021

Development of a Dihydroquinoline–Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the N-Methyl-d-aspartate Receptor

por D’Erasmo, Michael P., Akins, Nicholas S., Ma, Peipei, Jing, Yao, Swanger, Sharon A., Sharma, Savita K., Bartsch, Perry W., Menaldino, David S., Arcoria, Paul J., Bui, Thi-Thien, Pons-Bennaceur, Alexandre, Le, Phuong, Allen, James P., Ullman, Elijah Z., Nocilla, Kelsey A., Zhang, Jing, Perszyk, Riley E., Kim, Sukhan, Acker, Timothy M., Taz, Azmain, Burton, Samantha L., Coe, Kevin, Fritzemeier, Russell G., Burnashev, Nail, Yuan, Hongjie, Liotta, Dennis C., Traynelis, Stephen F.
Publicado 2023