Senataxin and R-loops homeostasis: multifaced implications in carcinogenesis

por Gatti, Veronica, De Domenico, Sara, Melino, Gerry, Peschiaroli, Angelo
Publicado 2023

Modification of Cul1 regulates its association with proteasomal subunits

por Bloom, Joanna, Peschiaroli, Angelo, DeMartino, George, Pagano, Michele
Publicado 2006

The Impact of the Ubiquitin System in the Pathogenesis of Squamous Cell Carcinomas

por Gatti, Veronica, Bernassola, Francesca, Talora, Claudio, Melino, Gerry, Peschiaroli, Angelo
Publicado 2020

ΔNp63 in squamous cell carcinoma: defining the oncogenic routes affecting epigenetic landscape and tumour microenvironment

por Gatti, Veronica, Fierro, Claudia, Annicchiarico‐Petruzzelli, Margherita, Melino, Gerry, Peschiaroli, Angelo
Publicado 2019

p63 at the Crossroads between Stemness and Metastasis in Breast Cancer

por Gatti, Veronica, Bongiorno-Borbone, Lucilla, Fierro, Claudia, Annicchiarico-Petruzzelli, Margherita, Melino, Gerry, Peschiaroli, Angelo
Publicado 2019

Anti-tumoral effect of desmethylclomipramine in lung cancer stem cells

por Bongiorno-Borbone, Lucilla, Giacobbe, Arianna, Compagnone, Mirco, Eramo, Adriana, De Maria, Ruggero, Peschiaroli, Angelo, Melino, Gerry
Publicado 2015

ΔNp63 regulates the expression of hyaluronic acid-related genes in breast cancer cells

por Gatti, Veronica, Fierro, Claudia, Compagnone, Mirco, Giangrazi, Federica, Markert, Elke Katrin, Bongiorno-Borbone, Lucilla, Melino, Gerry, Peschiaroli, Angelo
Publicado 2018

Setdb1, a novel interactor of ΔNp63, is involved in breast tumorigenesis

por Regina, Carla, Compagnone, Mirco, Peschiaroli, Angelo, Lena, AnnaMaria, Annicchiarico-Petruzzelli, Margherita, Piro, Maria Cristina, Melino, Gerry, Candi, Eleonora
Publicado 2016

Spastin recovery in hereditary spastic paraplegia by preventing neddylation-dependent degradation

por Sardina, Francesca, Pisciottani, Alessandra, Ferrara, Manuela, Valente, Davide, Casella, Marialuisa, Crescenzi, Marco, Peschiaroli, Angelo, Casali, Carlo, Soddu, Silvia, Grierson, Andrew J, Rinaldo, Cinzia
Publicado 2020

ΔNp63 promotes IGF1 signalling through IRS1 in squamous cell carcinoma

por Frezza, Valentina, Fierro, Claudia, Gatti, Elena, Peschiaroli, Angelo, Lena, Anna Maria, Petruzzelli, Margherita Annicchiarico, Candi, Eleonora, Anemona, Lucia, Mauriello, Alessandro, Pelicci, Pier Giuseppe, Melino, Gerry, Bernassola, Francesca
Publicado 2018

ΔNp63-Senataxin circuit controls keratinocyte differentiation by promoting the transcriptional termination of epidermal genes

por Gatti, Veronica, Fierro, Claudia, Compagnone, Mirco, La Banca, Veronica, Mauriello, Alessandro, Montanaro, Manuela, Scalera, Stefano, De Nicola, Francesca, Candi, Eleonora, Ricci, Francesco, Fania, Luca, Melino, Gerry, Peschiaroli, Angelo
Publicado 2022

The long non-coding RNA NEAT1 is a ΔNp63 target gene modulating epidermal differentiation

por Fierro, Claudia, Gatti, Veronica, La Banca, Veronica, De Domenico, Sara, Scalera, Stefano, Corleone, Giacomo, Fanciulli, Maurizio, De Nicola, Francesca, Mauriello, Alessandro, Montanaro, Manuela, Calin, George A., Melino, Gerry, Peschiaroli, Angelo
Publicado 2023

HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα

por Di Rita, Anthea, Peschiaroli, Angelo, D′Acunzo, Pasquale, Strobbe, Daniela, Hu, Zehan, Gruber, Jens, Nygaard, Mads, Lambrughi, Matteo, Melino, Gerry, Papaleo, Elena, Dengjel, Jörn, El Alaoui, Said, Campanella, Michelangelo, Dötsch, Volker, Rogov, Vladimir V., Strappazzon, Flavie, Cecconi, Francesco
Publicado 2018

A novel oral micellar fenretinide formulation with enhanced bioavailability and antitumour activity against multiple tumours from cancer stem cells

por Orienti, Isabella, Salvati, Valentina, Sette, Giovanni, Zucchetti, Massimo, Bongiorno-Borbone, Lucilla, Peschiaroli, Angelo, Zolla, Lello, Francescangeli, Federica, Ferrari, Mariella, Matteo, Cristina, Bello, Ezia, Di Virgilio, Antonio, Falchi, Mario, De Angelis, Maria Laura, Baiocchi, Marta, Melino, Gerry, De Maria, Ruggero, Zeuner, Ann, Eramo, Adriana
Publicado 2019

A new bioavailable fenretinide formulation with antiproliferative, antimetabolic, and cytotoxic effects on solid tumors

por Orienti, Isabella, Francescangeli, Federica, De Angelis, Maria Laura, Fecchi, Katia, Bongiorno-Borbone, Lucilla, Signore, Michele, Peschiaroli, Angelo, Boe, Alessandra, Bruselles, Alessandro, Costantino, Angelita, Eramo, Adriana, Salvati, Valentina, Sette, Giovanni, Contavalli, Paola, Zolla, Lello, Oki, Toshihiko, Kitamura, Toshio, Spada, Massimo, Giuliani, Alessandro, Baiocchi, Marta, La Torre, Filippo, Melino, Gerry, Tartaglia, Marco, De Maria, Ruggero, Zeuner, Ann
Publicado 2019

ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP

por Bufalieri, Francesca, Infante, Paola, Bernardi, Flavia, Caimano, Miriam, Romania, Paolo, Moretti, Marta, Lospinoso Severini, Ludovica, Talbot, Julie, Melaiu, Ombretta, Tanori, Mirella, Di Magno, Laura, Bellavia, Diana, Capalbo, Carlo, Puget, Stéphanie, De Smaele, Enrico, Canettieri, Gianluca, Guardavaccaro, Daniele, Busino, Luca, Peschiaroli, Angelo, Pazzaglia, Simonetta, Giannini, Giuseppe, Melino, Gerry, Locatelli, Franco, Gulino, Alberto, Ayrault, Olivier, Fruci, Doriana, Di Marcotullio, Lucia
Publicado 2019