Two clusters of surface-exposed amino acid residues enable high-affinity binding of retinal degeneration-3 (RD3) protein to retinal guanylyl cyclase

por Peshenko, Igor V., Dizhoor, Alexander M.
Publicado 2020

Regulation of retinal membrane guanylyl cyclase (RetGC) by negative calcium feedback and RD3 protein

por Dizhoor, Alexander M., Peshenko, Igor V.
Publicado 2021

Correction to: Regulation of retinal membrane guanylyl cyclase (RetGC) by negative calcium feedback and RD3 protein

por Dizhoor, Alexander M., Peshenko, Igor V.
Publicado 2021

Interaction of GCAP1 with retinal guanylyl cyclase and calcium: sensitivity to fatty acylation

por Peshenko, Igor V., Olshevskaya, Elena V., Dizhoor, Alexander M.
Publicado 2012

GUCY2D mutations in retinal guanylyl cyclase 1 provide biochemical reasons for dominant cone–rod dystrophy but not for stationary night blindness

por Peshenko, Igor V., Olshevskaya, Elena V., Dizhoor, Alexander M.
Publicado 2021

Retinal degeneration-3 protein promotes photoreceptor survival by suppressing activation of guanylyl cyclase rather than accelerating GMP recycling

por Dizhoor, Alexander M., Olshevskaya, Elena V., Peshenko, Igor V.
Publicado 2021

Retinal degeneration-3 protein attenuates photoreceptor degeneration in transgenic mice expressing dominant mutation of human retinal guanylyl cyclase

por Peshenko, Igor V., Olshevskaya, Elena V., Dizhoor, Alexander M.
Publicado 2021

Structural Insights for Activation of Retinal Guanylate Cyclase by GCAP1

por Lim, Sunghyuk, Peshenko, Igor V., Dizhoor, Alexander M., Ames, James B.
Publicado 2013

Enzymatic Relay Mechanism Stimulates Cyclic GMP Synthesis in Rod Photoresponse: Biochemical and Physiological Study in Guanylyl Cyclase Activating Protein 1 Knockout Mice

por Makino, Clint L., Wen, Xiao-Hong, Olshevskaya, Elena V., Peshenko, Igor V., Savchenko, Andrey B., Dizhoor, Alexander M.
Publicado 2012

Retinal guanylyl cyclase activating protein 1 forms a functional dimer

por Lim, Sunghyuk, Roseman, Graham, Peshenko, Igor, Manchala, Grace, Cudia, Diana, Dizhoor, Alexander M., Millhauser, Glenn, Ames, James B.
Publicado 2018

Functional study of two biochemically unusual mutations in GUCY2D Leber congenital amaurosis expressed via adenoassociated virus vector in mouse retinas

por Boye, Sanford L., Olshevskaya, Elena V., Peshenko, Igor V., McCullough, K. Tyler, Boye, Shannon E., Dizhoor, Alexander M.
Publicado 2016

Safety and improved efficacy signals following gene therapy in childhood blindness caused by GUCY2D mutations

por Jacobson, Samuel G., Cideciyan, Artur V., Ho, Allen C., Peshenko, Igor V., Garafalo, Alexandra V., Roman, Alejandro J., Sumaroka, Alexander, Wu, Vivian, Krishnan, Arun K., Sheplock, Rebecca, Boye, Sanford L., Dizhoor, Alexander M., Boye, Shannon E.
Publicado 2021

Night vision restored in days after decades of congenital blindness

por Jacobson, Samuel G., Cideciyan, Artur V., Ho, Allen C., Roman, Alejandro J., Wu, Vivian, Garafalo, Alexandra V., Sumaroka, Alexander, Krishnan, Arun K., Swider, Malgorzata, Mascio, Abraham A., Kay, Christine N., Yoon, Dan, Fujita, Kenji P., Boye, Sanford L., Peshenko, Igor V., Dizhoor, Alexander M., Boye, Shannon E.
Publicado 2022