Structural and mechanistic basis for a novel mode of glycosyltransferase inhibition

por Pesnot, Thomas, Jørgensen, Rene, Palcic, Monica M., Wagner, Gerd K.
Publicado 2010

Novel UDP-GalNAc Derivative Structures Provide Insight into the Donor Specificity of Human Blood Group Glycosyltransferase

por Wagner, Gerd K., Pesnot, Thomas, Palcic, Monica M., Jørgensen, Rene
Publicado 2015

Base-modified Donor Analogues Reveal Novel Dynamic Features of a Glycosyltransferase

por Jørgensen, René, Pesnot, Thomas, Lee, Ho Jun, Palcic, Monica M., Wagner, Gerd K.
Publicado 2013

One–Pot Phosphate-Mediated Synthesis of Novel 1,3,5-Trisubstituted Pyridinium Salts: A New Family of S. aureus Inhibitors

por Pesnot, Thomas, Gershater, Markus C., Edwards, Martin, Ward, John M., Hailes, Helen C.
Publicado 2017

Structural Evidence for the Dopamine-First Mechanism of Norcoclaurine Synthase

por Lichman, Benjamin R., Sula, Altin, Pesnot, Thomas, Hailes, Helen C., Ward, John M., Keep, Nicholas H.
Publicado 2017

‘Dopamine-first’ mechanism enables the rational engineering of the norcoclaurine synthase aldehyde activity profile

por Lichman, Benjamin R, Gershater, Markus C, Lamming, Eleanor D, Pesnot, Thomas, Sula, Altin, Keep, Nicholas H, Hailes, Helen C, Ward, John M
Publicado 2015

Enzymatic synthesis of nucleobase-modified UDP-sugars: scope and limitations

por Wagstaff, Ben A., Rejzek, Martin, Pesnot, Thomas, Tedaldi, Lauren M., Caputi, Lorenzo, O’Neill, Ellis C., Benini, Stefano, Wagner, Gerd K., Field, Robert A.
Publicado 2015

2- and 3-substituted imidazo[1,2-a]pyrazines as inhibitors of bacterial type IV secretion

por Sayer, James R., Walldén, Karin, Pesnot, Thomas, Campbell, Frederick, Gane, Paul J., Simone, Michela, Koss, Hans, Buelens, Floris, Boyle, Timothy P., Selwood, David L., Waksman, Gabriel, Tabor, Alethea B.
Publicado 2014

Tetrahydroisoquinolines affect the whole-cell phenotype of Mycobacterium tuberculosis by inhibiting the ATP-dependent MurE ligase

por Guzman, Juan D., Pesnot, Thomas, Barrera, Diana A., Davies, Heledd M., McMahon, Eleanor, Evangelopoulos, Dimitrios, Mortazavi, Parisa N., Munshi, Tulika, Maitra, Arundhati, Lamming, Eleanor D., Angell, Richard, Gershater, Markus C., Redmond, Joanna M., Needham, Deborah, Ward, John M., Cuca, Luis E., Hailes, Helen C., Bhakta, Sanjib
Publicado 2015