Cohesion is established during DNA replication utilising chromosome associated cohesin rings as well as those loaded de novo onto nascent DNAs

por Srinivasan, Madhusudhan, Fumasoni, Marco, Petela, Naomi J, Murray, Andrew, Nasmyth, Kim A
Publicado 2020

Biological chromodynamics: a general method for measuring protein occupancy across the genome by calibrating ChIP-seq

por Hu, Bin, Petela, Naomi, Kurze, Alexander, Chan, Kok-Lung, Chapard, Christophe, Nasmyth, Kim
Publicado 2015

Crystal Structure of the Cohesin Gatekeeper Pds5 and in Complex with Kleisin Scc1

por Lee, Byung-Gil, Roig, Maurici B., Jansma, Marijke, Petela, Naomi, Metson, Jean, Nasmyth, Kim, Löwe, Jan
Publicado 2016

Conformational dynamics of cohesin/Scc2 loading complex are regulated by Smc3 acetylation and ATP binding

por Kaushik, Aditi, Than, Thane, Petela, Naomi J., Voulgaris, Menelaos, Percival, Charlotte, Daniels, Peter, Rafferty, John B., Nasmyth, Kim A., Hu, Bin
Publicado 2023

Scc2 counteracts a Wapl-independent mechanism that releases cohesin from chromosomes during G1

por Srinivasan, Madhusudhan, Petela, Naomi J, Scheinost, Johanna C, Collier, James, Voulgaris, Menelaos, B Roig, Maurici, Beckouët, Frederic, Hu, Bin, Nasmyth, Kim A
Publicado 2019

Transport of DNA within cohesin involves clamping on top of engaged heads by Scc2 and entrapment within the ring by Scc3

por Collier, James E, Lee, Byung-Gil, Roig, Maurici Brunet, Yatskevich, Stanislav, Petela, Naomi J, Metson, Jean, Voulgaris, Menelaos, Gonzalez Llamazares, Andres, Löwe, Jan, Nasmyth, Kim A
Publicado 2020

Releasing Activity Disengages Cohesin’s Smc3/Scc1 Interface in a Process Blocked by Acetylation

por Beckouët, Frederic, Srinivasan, Madhusudhan, Roig, Maurici Brunet, Chan, Kok-Lung, Scheinost, Johanna C., Batty, Paul, Hu, Bin, Petela, Naomi, Gligoris, Thomas, Smith, Alexandra C., Strmecki, Lana, Rowland, Benjamin D., Nasmyth, Kim
Publicado 2016

Cohesin Releases DNA through Asymmetric ATPase-Driven Ring Opening

por Elbatsh, Ahmed M.O., Haarhuis, Judith H.I., Petela, Naomi, Chapard, Christophe, Fish, Alexander, Celie, Patrick H., Stadnik, Magda, Ristic, Dejan, Wyman, Claire, Medema, René H., Nasmyth, Kim, Rowland, Benjamin D.
Publicado 2016

Scc2 Is a Potent Activator of Cohesin’s ATPase that Promotes Loading by Binding Scc1 without Pds5

por Petela, Naomi J., Gligoris, Thomas G., Metson, Jean, Lee, Byung-Gil, Voulgaris, Menelaos, Hu, Bin, Kikuchi, Sotaro, Chapard, Christophe, Chen, Wentao, Rajendra, Eeson, Srinivisan, Madhusudhan, Yu, Hongtao, Löwe, Jan, Nasmyth, Kim A.
Publicado 2018

The Cohesin Ring Uses Its Hinge to Organize DNA Using Non-topological as well as Topological Mechanisms

por Srinivasan, Madhusudhan, Scheinost, Johanna C., Petela, Naomi J., Gligoris, Thomas G., Wissler, Maria, Ogushi, Sugako, Collier, James E., Voulgaris, Menelaos, Kurze, Alexander, Chan, Kok-Lung, Hu, Bin, Costanzo, Vincenzo, Nasmyth, Kim A.
Publicado 2018

Folding of cohesin’s coiled coil is important for Scc2/4-induced association with chromosomes

por Petela, Naomi J, Gonzalez Llamazares, Andres, Dixon, Sarah, Hu, Bin, Lee, Byung-Gil, Metson, Jean, Seo, Heekyo, Ferrer-Harding, Antonio, Voulgaris, Menelaos, Gligoris, Thomas, Collier, James, Oh, Byung-Ha, Löwe, Jan, Nasmyth, Kim A
Publicado 2021