Seeding and transgenic overexpression of alpha‐synuclein triggers dendritic spine pathology in the neocortex

por Blumenstock, Sonja, Rodrigues, Eva F, Peters, Finn, Blazquez‐Llorca, Lidia, Schmidt, Felix, Giese, Armin, Herms, Jochen
Publicado 2017

Tau deletion reduces plaque‐associated BACE1 accumulation and decelerates plaque formation in a mouse model of Alzheimer's disease

por Peters, Finn, Salihoglu, Hazal, Pratsch, Katrin, Herzog, Etienne, Pigoni, Martina, Sgobio, Carmelo, Lichtenthaler, Stefan F, Neumann, Ulf, Herms, Jochen
Publicado 2019

Intraneuronal APP and extracellular Aβ independently cause dendritic spine pathology in transgenic mouse models of Alzheimer’s disease

por Zou, Chengyu, Montagna, Elena, Shi, Yuan, Peters, Finn, Blazquez-Llorca, Lidia, Shi, Song, Filser, Severin, Dorostkar, Mario M., Herms, Jochen
Publicado 2015

β-secretase inhibition prevents structural spine plasticity deficits in App(NL-G-F) mice

por Blume, Tanja, Filser, Severin, Sgobio, Carmelo, Peters, Finn, Neumann, Ulf, Shimshek, Derya, Saito, Takashi, Saido, Takaomi C., Brendel, Matthias, Herms, Jochen
Publicado 2022

BACE1 inhibition more effectively suppresses initiation than progression of β-amyloid pathology

por Peters, Finn, Salihoglu, Hazal, Rodrigues, Eva, Herzog, Etienne, Blume, Tanja, Filser, Severin, Dorostkar, Mario, Shimshek, Derya R., Brose, Nils, Neumann, Ulf, Herms, Jochen
Publicado 2018

Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study

por Blume, Tanja, Focke, Carola, Peters, Finn, Deussing, Maximilian, Albert, Nathalie L., Lindner, Simon, Gildehaus, Franz-Josef, von Ungern-Sternberg, Barbara, Ozmen, Laurence, Baumann, Karlheinz, Bartenstein, Peter, Rominger, Axel, Herms, Jochen, Brendel, Matthias
Publicado 2018

Comparison of (18)F-T807 and (18)F-THK5117 PET in a Mouse Model of Tau Pathology

por Brendel, Matthias, Yousefi, Behrooz H., Blume, Tanja, Herz, Michael, Focke, Carola, Deussing, Maximilian, Peters, Finn, Lindner, Simon, von Ungern-Sternberg, Barbara, Drzezga, Alexander, Bartenstein, Peter, Haass, Christian, Okamura, Nobuyuki, Herms, Jochen, Yakushev, Igor, Rominger, Axel
Publicado 2018

The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell development and migration

por Schoof, Melanie, Launspach, Michael, Holdhof, Dörthe, Nguyen, Lynhda, Engel, Verena, Filser, Severin, Peters, Finn, Immenschuh, Jana, Hellwig, Malte, Niesen, Judith, Mall, Volker, Ertl-Wagner, Birgit, Hagel, Christian, Spohn, Michael, Lutz, Beat, Sedlacik, Jan, Indenbirken, Daniela, Merk, Daniel J., Schüller, Ulrich
Publicado 2019

Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer’s disease tau

por Brendel, Matthias, Deussing, Maximilian, Blume, Tanja, Kaiser, Lena, Probst, Federico, Overhoff, Felix, Peters, Finn, von Ungern-Sternberg, Barbara, Ryazanov, Sergey, Leonov, Andrei, Griesinger, Christian, Zwergal, Andreas, Levin, Johannes, Bartenstein, Peter, Yakushev, Igor, Cumming, Paul, Boening, Guido, Ziegler, Sibylle, Herms, Jochen, Giese, Armin, Rominger, Axel
Publicado 2019

Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition

por Colombo, Alessio Vittorio, Sadler, Rebecca Katie, Llovera, Gemma, Singh, Vikramjeet, Roth, Stefan, Heindl, Steffanie, Sebastian Monasor, Laura, Verhoeven, Aswin, Peters, Finn, Parhizkar, Samira, Kamp, Frits, Gomez de Aguero, Mercedes, MacPherson, Andrew J, Winkler, Edith, Herms, Jochen, Benakis, Corinne, Dichgans, Martin, Steiner, Harald, Giera, Martin, Haass, Christian, Tahirovic, Sabina, Liesz, Arthur
Publicado 2021

Benefits of global mutant huntingtin lowering diminish over time in a Huntington’s disease mouse model

por Marchionini, Deanna M., Liu, Jeh-Ping, Ambesi-Impiombato, Alberto, Kerker, Kimberly, Cirillo, Kim, Bansal, Mukesh, Mushlin, Rich, Brunner, Daniela, Ramboz, Sylvie, Kwan, Mei, Kuhlbrodt, Kirsten, Tillack, Karsten, Peters, Finn, Rauhala, Leena, Obenauer, John, Greene, Jonathan R., Hartl, Christopher, Khetarpal, Vinod, Lager, Brenda, Rosinski, Jim, Aaronson, Jeff, Alam, Morshed, Signer, Ethan, Muñoz-Sanjuán, Ignacio, Howland, David, Zeitlin, Scott O.
Publicado 2022

Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation

por Biechele, Gloria, Blume, Tanja, Deussing, Maximilian, Zott, Benedikt, Shi, Yuan, Xiang, Xianyuan, Franzmeier, Nicolai, Kleinberger, Gernot, Peters, Finn, Ochs, Katharina, Focke, Carola, Sacher, Christian, Wind, Karin, Schmidt, Claudio, Lindner, Simon, Gildehaus, Franz-Josef, Eckenweber, Florian, Beyer, Leonie, von Ungern-Sternberg, Barbara, Bartenstein, Peter, Baumann, Karlheinz, Dorostkar, Mario M., Rominger, Axel, Cumming, Paul, Willem, Michael, Adelsberger, Helmuth, Herms, Jochen, Brendel, Matthias
Publicado 2021

Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition

por Blume, Tanja, Deussing, Maximilian, Biechele, Gloria, Peters, Finn, Zott, Benedikt, Schmidt, Claudio, Franzmeier, Nicolai, Wind, Karin, Eckenweber, Florian, Sacher, Christian, Shi, Yuan, Ochs, Katharina, Kleinberger, Gernot, Xiang, Xianyuan, Focke, Carola, Lindner, Simon, Gildehaus, Franz-Josef, Beyer, Leonie, von Ungern-Sternberg, Barbara, Bartenstein, Peter, Baumann, Karlheinz, Adelsberger, Helmuth, Rominger, Axel, Cumming, Paul, Willem, Michael, Dorostkar, Mario M., Herms, Jochen, Brendel, Matthias
Publicado 2022