KIT promotes tumor stroma formation and counteracts tumor-suppressive TGFβ signaling in colorectal cancer

por Küçükköse, Emre, Peters, Niek A., Ubink, Inge, van Keulen, Veere A. M., Daghighian, Roxanna, Verheem, André, Laoukili, Jamila, Kranenburg, Onno
Publicado 2022

Downregulation of DNA repair proteins and increased DNA damage in hypoxic colon cancer cells is a therapeutically exploitable vulnerability

por Jongen, Jennifer M. J., van der Waals, Lizet M., Trumpi, Kari, Laoukili, Jamila, Peters, Niek A., Schenning-van Schelven, Susanne J., Govaert, Klaas M., Borel Rinkes, Inne H. M., Kranenburg, Onno
Publicado 2017

Dynamic Visualization of TGF-β/SMAD3 Transcriptional Responses in Single Living Cells

por Marvin, Dieuwke L., You, Li, Bornes, Laura, van Dinther, Maarten, Peters, Niek, Dang, Hao, Hakuno, Sarah K., Hornsveld, Marten, Kranenburg, Onno, van Rheenen, Jacco, Rohling, Jos H. T., Chien, Miao-Ping, ten Dijke, Peter, Ritsma, Laila
Publicado 2022

Co-cultures of colon cancer cells and cancer-associated fibroblasts recapitulate the aggressive features of mesenchymal-like colon cancer

por Strating, Esther, Verhagen, Mathijs P., Wensink, Emerens, Dünnebach, Ester, Wijler, Liza, Aranguren, Itziar, De la Cruz, Alberto Sanchez, Peters, Niek A., Hageman, Joris H., van der Net, Mirjam M. C., van Schelven, Susanne, Laoukili, Jamila, Fodde, Riccardo, Roodhart, Jeanine, Nierkens, Stefan, Snippert, Hugo, Gloerich, Martijn, Rinkes, Inne Borel, Elias, Sjoerd G., Kranenburg, Onno
Publicado 2023

Liver Colonization by Colorectal Cancer Metastases Requires YAP-Controlled Plasticity at the Micrometastatic Stage

por Heinz, Maria C., Peters, Niek A., Oost, Koen C., Lindeboom, Rik G.H., van Voorthuijsen, Lisa, Fumagalli, Arianna, van der Net, Mirjam C., de Medeiros, Gustavo, Hageman, Joris H., Verlaan-Klink, Ingrid, Borel Rinkes, Inne H.M., Liberali, Prisca, Gloerich, Martijn, van Rheenen, Jacco, Vermeulen, Michiel, Kranenburg, Onno, Snippert, Hugo J.G.
Publicado 2022

Consensus molecular subtype 4 (CMS4)-targeted therapy in primary colon cancer: A proof-of-concept study

por Peters, Niek A., Constantinides, Alexander, Ubink, Inge, van Kuik, Joyce, Bloemendal, Haiko J., van Dodewaard, Joyce M., Brink, Menno A., Schwartz, Thijs P., Lolkema, Martijn P.J.K., Lacle, Miangela M., Moons, Leon M., Geesing, Joost, van Grevenstein, Wilhelmina M.U., Roodhart, Jeanine M. L., Koopman, Miriam, Elias, Sjoerd G., Borel Rinkes, Inne H.M., Kranenburg, Onno
Publicado 2022

Outcomes and Risk Score for Distal Pancreatectomy with Celiac Axis Resection (DP-CAR): An International Multicenter Analysis

por Klompmaker, Sjors, Peters, Niek A., van Hilst, Jony, Bassi, Claudio, Boggi, Ugo, Busch, Olivier R., Niesen, Willem, Van Gulik, Thomas M., Javed, Ammar A., Kleeff, Jorg, Kawai, Manabu, Lesurtel, Mickael, Lombardo, Carlo, Moser, A. James, Okada, Ken-ichi, Popescu, Irinel, Prasad, Raj, Salvia, Roberto, Sauvanet, Alain, Sturesson, Christian, Weiss, Matthew J., Zeh, Herbert J., Zureikat, Amer H., Yamaue, Hiroki, Wolfgang, Christopher L., Hogg, Melissa E., Besselink, Marc G.
Publicado 2019