A Retrospective Evaluation of Allometry, Population Pharmacokinetics, and Physiologically‐Based Pharmacokinetics for Pediatric Dosing Using Clearance as a Surrogate

por Wu, Qier, Peters, Sheila Annie
Publicado 2019

Requirements to Establishing Confidence in Physiologically Based Pharmacokinetic (PBPK) Models and Overcoming Some of the Challenges to Meeting Them

por Peters, Sheila Annie, Dolgos, Hugues
Publicado 2019

Can Mechanistic Static Models for Drug-Drug Interactions Support Regulatory Filing for Study Waivers and Label Recommendations?

por Gomez-Mantilla, Jose David, Huang, Fenglei, Peters, Sheila Annie
Publicado 2023

A comparative evaluation of models to predict human intestinal metabolism from nonclinical data

por Yau, Estelle, Petersson, Carl, Dolgos, Hugues, Peters, Sheila Annie
Publicado 2017

Application of physiologically based biopharmaceutics modeling to understand the impact of dissolution differences on in vivo performance of immediate release products: The case of...

por Macwan, Joyce S., Fraczkiewicz, Grace, Bertolino, Mauro, Krüger, Phillip, Peters, Sheila‐Annie
Publicado 2021

Predicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical Models

por Peters, Sheila Annie, Jones, Christopher R., Ungell, Anna-Lena, Hatley, Oliver J. D.
Publicado 2016

Evaluating the Role of Solubility in Oral Absorption of Poorly Water‐Soluble Drugs Using Physiologically‐Based Pharmacokinetic Modeling

por Fink, Christina, Sun, Dajun, Wagner, Knut, Schneider, Melanie, Bauer, Holger, Dolgos, Hugues, Mäder, Karsten, Peters, Sheila‐Annie
Publicado 2019

Proteomics of colorectal cancer liver metastasis: A quantitative focus on drug elimination and pharmacodynamics effects

por Vasilogianni, Areti‐Maria, Al‐Majdoub, Zubida M., Achour, Brahim, Peters, Sheila Annie, Rostami‐Hodjegan, Amin, Barber, Jill
Publicado 2021

Proteomic quantification of receptor tyrosine kinases involved in the development and progression of colorectal cancer liver metastasis

por Vasilogianni, Areti-Maria, Al-Majdoub, Zubida M., Achour, Brahim, Peters, Sheila Annie, Rostami-Hodjegan, Amin, Barber, Jill
Publicado 2023

Recommendations for the Design of Clinical Drug–Drug Interaction Studies With Itraconazole Using a Mechanistic Physiologically‐Based Pharmacokinetic Model

por Chen, Yuan, Cabalu, Tamara D., Callegari, Ernesto, Einolf, Heidi, Liu, Lichuan, Parrott, Neil, Peters, Sheila Annie, Schuck, Edgar, Sharma, Pradeep, Tracey, Helen, Upreti, Vijay V., Zheng, Ming, Zhu, Andy Z.X., Hall, Stephen D.
Publicado 2019

Physiologically‐Based Pharmacokinetic Modeling in Renal and Hepatic Impairment Populations: A Pharmaceutical Industry Perspective

por Heimbach, Tycho, Chen, Yuan, Chen, Jun, Dixit, Vaishali, Parrott, Neil, Peters, Sheila Annie, Poggesi, Italo, Sharma, Pradeep, Snoeys, Jan, Shebley, Mohamad, Tai, Guoying, Tse, Susanna, Upreti, Vijay V., Wang, Ying‐Hong, Tsai, Alice, Xia, Binfeng, Zheng, Ming, Zhu, Andy Z.X., Hall, Stephen
Publicado 2020

Physiologically Based Pharmacokinetic Model Qualification and Reporting Procedures for Regulatory Submissions: A Consortium Perspective

por Shebley, Mohamad, Sandhu, Punam, Emami Riedmaier, Arian, Jamei, Masoud, Narayanan, Rangaraj, Patel, Aarti, Peters, Sheila Annie, Reddy, Venkatesh Pilla, Zheng, Ming, de Zwart, Loeckie, Beneton, Maud, Bouzom, Francois, Chen, Jun, Chen, Yuan, Cleary, Yumi, Collins, Christiane, Dickinson, Gemma L., Djebli, Nassim, Einolf, Heidi J., Gardner, Iain, Huth, Felix, Kazmi, Faraz, Khalil, Feras, Lin, Jing, Odinecs, Aleksandrs, Patel, Chirag, Rong, Haojing, Schuck, Edgar, Sharma, Pradeep, Wu, Shu‐Pei, Xu, Yang, Yamazaki, Shinji, Yoshida, Kenta, Rowland, Malcolm
Publicado 2018