IKBKB reduces huntingtin aggregation by phosphorylating serine 13 via a non-canonical IKK pathway

por Cariulo, Cristina, Martufi, Paola, Verani, Margherita, Toledo-Sherman, Leticia, Lee, Ramee, Dominguez, Celia, Petricca, Lara, Caricasole, Andrea
Publicado 2023

Comparative Analysis of Total Alpha-Synuclein (αSYN) Immunoassays Reveals That They Do Not Capture the Diversity of Modified αSYN Proteoforms

por Petricca, Lara, Chiki, Nour, Hanna-El-Daher, Layane, Aeschbach, Lorène, Burai, Ritwik, Stoops, Erik, Fares, Mohamed-Bilal, Lashuel, Hilal A.
Publicado 2022

Development of an ELISA assay for the quantification of soluble huntingtin in human blood cells

por Massai, Luisa, Petricca, Lara, Magnoni, Letizia, Rovetini, Luca, Haider, Salman, Andre, Ralph, Tabrizi, Sarah J, Süssmuth, Sigurd D, Landwehrmeyer, Bernhard G, Caricasole, Andrea, Pollio, Giuseppe, Bernocco, Simonetta
Publicado 2013

Phospho-S129 Alpha-Synuclein Is Present in Human Plasma but Not in Cerebrospinal Fluid as Determined by an Ultrasensitive Immunoassay

por Cariulo, Cristina, Martufi, Paola, Verani, Margherita, Azzollini, Lucia, Bruni, Giordana, Weiss, Andreas, Deguire, Sean M., Lashuel, Hilal A., Scaricamazza, Eugenia, Sancesario, Giulia Maria, Schirinzi, Tommaso, Mercuri, Nicola Biagio, Sancesario, Giuseppe, Caricasole, Andrea, Petricca, Lara
Publicado 2019

Phosphorylation of huntingtin at residue T3 is decreased in Huntington’s disease and modulates mutant huntingtin protein conformation

por Cariulo, Cristina, Azzollini, Lucia, Verani, Margherita, Martufi, Paola, Boggio, Roberto, Chiki, Anass, Deguire, Sean M., Cherubini, Marta, Gines, Silvia, Marsh, J. Lawrence, Conforti, Paola, Cattaneo, Elena, Santimone, Iolanda, Squitieri, Ferdinando, Lashuel, Hilal A., Petricca, Lara, Caricasole, Andrea
Publicado 2017

Polyglutamine- and Temperature-Dependent Conformational Rigidity in Mutant Huntingtin Revealed by Immunoassays and Circular Dichroism Spectroscopy

por Fodale, Valentina, Kegulian, Natalie C., Verani, Margherita, Cariulo, Cristina, Azzollini, Lucia, Petricca, Lara, Daldin, Manuel, Boggio, Roberto, Padova, Alessandro, Kuhn, Rainer, Pacifici, Robert, Macdonald, Douglas, Schoenfeld, Ryan C., Park, Hyunsun, Isas, J. Mario, Langen, Ralf, Weiss, Andreas, Caricasole, Andrea
Publicado 2014

TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models

por Hegde, Ramanath Narayana, Chiki, Anass, Petricca, Lara, Martufi, Paola, Arbez, Nicolas, Mouchiroud, Laurent, Auwerx, Johan, Landles, Christian, Bates, Gillian P, Singh‐Bains, Malvindar K, Dragunow, Mike, Curtis, Maurice A, Faull, Richard LM, Ross, Christopher A, Caricasole, Andrea, Lashuel, Hilal A
Publicado 2020

Striatal infusion of cholesterol promotes dose‐dependent behavioral benefits and exerts disease‐modifying effects in Huntington's disease mice

por Birolini, Giulia, Valenza, Marta, Di Paolo, Eleonora, Vezzoli, Elena, Talpo, Francesca, Maniezzi, Claudia, Caccia, Claudio, Leoni, Valerio, Taroni, Franco, Bocchi, Vittoria D, Conforti, Paola, Sogne, Elisa, Petricca, Lara, Cariulo, Cristina, Verani, Margherita, Caricasole, Andrea, Falqui, Andrea, Biella, Gerardo, Cattaneo, Elena
Publicado 2020

Polyglutamine expansion affects huntingtin conformation in multiple Huntington’s disease models

por Daldin, Manuel, Fodale, Valentina, Cariulo, Cristina, Azzollini, Lucia, Verani, Margherita, Martufi, Paola, Spiezia, Maria Carolina, Deguire, Sean M., Cherubini, Marta, Macdonald, Douglas, Weiss, Andreas, Bresciani, Alberto, Vonsattel, Jean-Paul Gerard, Petricca, Lara, Marsh, J. Lawrence, Gines, Silvia, Santimone, Iolanda, Marano, Massimo, Lashuel, Hilal A., Squitieri, Ferdinando, Caricasole, Andrea
Publicado 2017