ZIP4H (TEX11) Deficiency in the Mouse Impairs Meiotic Double Strand Break Repair and the Regulation of Crossing Over

por Adelman, Carrie A., Petrini, John H. J.
Publicado 2008

ISG15 conjugation to proteins on nascent DNA mitigates DNA replication stress

por Wardlaw, Christopher P., Petrini, John H. J.
Publicado 2022

Functions of the MRE11 complex in the development and maintenance of oocytes

por Inagaki, Akiko, Roset, Ramon, Petrini, John H. J.
Publicado 2015

TRF2 Recruits RTEL1 to Telomeres in S Phase to Promote T-Loop Unwinding

por Sarek, Grzegorz, Vannier, Jean-Baptiste, Panier, Stephanie, Petrini, John H.J., Boulton, Simon J.
Publicado 2015

TRF2 Recruits RTEL1 to Telomeres in S Phase to Promote T-Loop Unwinding

por Sarek, Grzegorz, Vannier, Jean-Baptiste, Panier, Stephanie, Petrini, John H.J., Boulton, Simon J.
Publicado 2016

The Rad50 Coiled Coil Domain is indispensable for Mre11 complex functions

por Hohl, Marcel, Kwon, Youngho, Galván, Sandra Muñoz, Xue, Xiaoyu, Tous, Cristina, Aguilera, Andrés, Sung, Patrick, Petrini, John H.J.
Publicado 2011

The Telomeric Protein TRF2 Binds the ATM Kinase and Can Inhibit the ATM-Dependent DNA Damage Response

por Karlseder, Jan, Hoke, Kristina, Mirzoeva, Olga K, Bakkenist, Christopher, Kastan, Michael B, Petrini, John H. J, de Lange, Titia
Publicado 2004

Eukaryotic Rad50 Functions as A Rod-shaped Dimer

por Park, Young Bong, Hohl, Marcel, Padjasek, Michał, Jeong, Eunyoung, Jin, Kyeong Sik, Krężel, Artur, Petrini, John H. J., Cho, Yunje
Publicado 2017

RTEL1 influences the abundance and localization of TERRA RNA

por Ghisays, Fiorella, Garzia, Aitor, Wang, Hexiao, Canasto-Chibuque, Claudia, Hohl, Marcel, Savage, Sharon A., Tuschl, Thomas, Petrini, John H. J.
Publicado 2021

Nej1 Interacts with Mre11 to Regulate Tethering and Dna2 Binding at DNA Double-Strand Breaks

por Mojumdar, Aditya, Sorenson, Kyle, Hohl, Marcel, Toulouze, Mathias, Lees-Miller, Susan P., Dubrana, Karine, Petrini, John H.J., Cobb, Jennifer A.
Publicado 2019

Whole exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma

por Kannan, Kasthuri, Inagaki, Akiko, Silber, Joachim, Gorovets, Daniel, Zhang, Jianan, Kastenhuber, Edward R., Heguy, Adriana, Petrini, John H., Chan, Timothy A., Huse, Jason T.
Publicado 2012

The Rad50 hook domain regulates DNA damage signaling and tumorigenesis

por Roset, Ramon, Inagaki, Akiko, Hohl, Marcel, Brenet, Fabienne, Lafrance-Vanasse, Julien, Lange, Julian, Scandura, Joseph M., Tainer, John A., Keeney, Scott, Petrini, John H.J.
Publicado 2014

A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans

por Chansel-Da Cruz, Marie, Hohl, Marcel, Ceppi, Ilaria, Kermasson, Laëtitia, Maggiorella, Laurence, Modesti, Mauro, de Villartay, Jean-Pierre, Ileri, Talia, Cejka, Petr, Petrini, John H.J., Revy, Patrick
Publicado 2020

Chemical Genetics Reveals a Specific Requirement for Cdk2 Activity in the DNA Damage Response and Identifies Nbs1 as a Cdk2 Substrate in Human Cells

por Wohlbold, Lara, Merrick, Karl A., De, Saurav, Amat, Ramon, Kim, Jun Hyun, Larochelle, Stéphane, Allen, Jasmina J., Zhang, Chao, Shokat, Kevan M., Petrini, John H. J., Fisher, Robert P.
Publicado 2012

Modeling cancer genomic data in yeast reveals selection against ATM function during tumorigenesis

por Hohl, Marcel, Mojumdar, Aditya, Hailemariam, Sarem, Kuryavyi, Vitaly, Ghisays, Fiorella, Sorenson, Kyle, Chang, Matthew, Taylor, Barry S., Patel, Dinshaw J., Burgers, Peter M., Cobb, Jennifer A., Petrini, John H. J.
Publicado 2020

Aberrant Topoisomerase-1-DNA Lesions are Pathogenic in Neurodegenerative Genome Instability Syndromes

por Katyal, Sachin, Lee, Youngsoo, Nitiss, Karin C., Downing, Susanna M., Li, Yang, Shimada, Mikio, Zhao, Jingfeng, Russell, Helen R., Petrini, John H. J., Nitiss, John L., McKinnon, Peter J.
Publicado 2014

Mouse DCUN1D1 (SCCRO) is required for spermatogenetic individualization

por Huang, Guochang, Kaufman, Andrew J., Ryan, Russell J. H., Romin, Yevgeniy, Huryn, Laryssa, Bains, Sarina, Manova-Todorova, Katia, Morris, Patricia L., Hunnicutt, Gary R., Adelman, Carrie A., Petrini, John H. J., Ramanathan, Y., Singh, Bhuvanesh
Publicado 2019

Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway

por Lovejoy, Courtney A., Li, Wendi, Reisenweber, Steven, Thongthip, Supawat, Bruno, Joanne, de Lange, Titia, De, Saurav, Petrini, John H. J., Sung, Patricia A., Jasin, Maria, Rosenbluh, Joseph, Zwang, Yaara, Weir, Barbara A., Hatton, Charlie, Ivanova, Elena, Macconaill, Laura, Hanna, Megan, Hahn, William C., Lue, Neal F., Reddel, Roger R., Jiao, Yuchen, Kinzler, Kenneth, Vogelstein, Bert, Papadopoulos, Nickolas, Meeker, Alan K.
Publicado 2012

A Recessive Founder Mutation in Regulator of Telomere Elongation Helicase 1, RTEL1, Underlies Severe Immunodeficiency and Features of Hoyeraal Hreidarsson Syndrome

por Ballew, Bari J., Joseph, Vijai, De, Saurav, Sarek, Grzegorz, Vannier, Jean-Baptiste, Stracker, Travis, Schrader, Kasmintan A., Small, Trudy N., O'Reilly, Richard, Manschreck, Chris, Harlan Fleischut, Megan M., Zhang, Liying, Sullivan, John, Stratton, Kelly, Yeager, Meredith, Jacobs, Kevin, Giri, Neelam, Alter, Blanche P., Boland, Joseph, Burdett, Laurie, Offit, Kenneth, Boulton, Simon J., Savage, Sharon A., Petrini, John H. J.
Publicado 2013