Mechanisms and models of TDP-43 proteinopathies

por Petrucelli, Leonard
Publicado 2012

"What kills neurons in neurodegenerative diseases?", a review series in an open access journal

por Golde, Todd E, Petrucelli, Leonard
Publicado 2009

The role of tau in neurodegeneration

por Gendron, Tania F, Petrucelli, Leonard
Publicado 2009

Rodent Models of TDP-43 Proteinopathy: Investigating the Mechanisms of TDP-43-Mediated Neurodegeneration

por Gendron, Tania F., Petrucelli, Leonard
Publicado 2011

Does Obesity-Induced τ Phosphorylation Tip the Scale Toward Dementia?

por Gendron, Tania F., Zhang, Yong-Jie, Petrucelli, Leonard
Publicado 2013

The Ubiquitin-Proteasome Reporter GFPu Does Not Accumulate in Neurons of the R6/2 Transgenic Mouse Model of Huntington's Disease

por Bett, John S., Cook, Casey, Petrucelli, Leonard, Bates, Gillian P.
Publicado 2009

Progranulin axis and recent developments in frontotemporal lobar degeneration

por Nicholson, Alexandra M, Gass, Jennifer, Petrucelli, Leonard, Rademakers, Rosa
Publicado 2012

Cracking the cryptic code in amyotrophic lateral sclerosis and frontotemporal dementia: Towards therapeutic targets and biomarkers

por Akiyama, Tetsuya, Koike, Yuka, Petrucelli, Leonard, Gitler, Aaron D.
Publicado 2022

Acetylation: a new key to unlock tau’s role in neurodegeneration

por Cook, Casey, Stankowski, Jeannette N, Carlomagno, Yari, Stetler, Caroline, Petrucelli, Leonard
Publicado 2014

Cross-sectional and longitudinal measures of chitinase proteins in amyotrophic lateral sclerosis and expression of CHI3L1 in activated astrocytes

por Vu, Lucas, An, Jiyan, Kovalik, Tina, Gendron, Tania, Petrucelli, Leonard, Bowser, Robert
Publicado 2020

Cellular and pathological heterogeneity of primary tauopathies

por Chung, Dah-eun Chloe, Roemer, Shanu, Petrucelli, Leonard, Dickson, Dennis W.
Publicado 2021

Divergent Phenotypes in Mutant TDP-43 Transgenic Mice Highlight Potential Confounds in TDP-43 Transgenic Modeling

por D’Alton, Simon, Altshuler, Marcelle, Cannon, Ashley, Dickson, Dennis W., Petrucelli, Leonard, Lewis, Jada
Publicado 2014

Three Repeat Isoforms of Tau Inhibit Assembly of Four Repeat Tau Filaments

por Adams, Stephanie J., DeTure, Michael A., McBride, Melinda, Dickson, Dennis W., Petrucelli, Leonard
Publicado 2010

TDP-1/TDP-43 Regulates Stress Signaling and Age-Dependent Proteotoxicity in Caenorhabditis elegans

por Vaccaro, Alexandra, Tauffenberger, Arnaud, Ash, Peter E. A., Carlomagno, Yari, Petrucelli, Leonard, Parker, J. Alex
Publicado 2012

ARHGEF28 p.Lys280Metfs40Ter in an amyotrophic lateral sclerosis family with a C9orf72 expansion

por Farhan, Sali M.K., Gendron, Tania F., Petrucelli, Leonard, Hegele, Robert A., Strong, Michael J.
Publicado 2017

C-terminal and full length TDP-43 specie differ according to FTLD-TDP lesion type but not genetic mutation

por Josephs, Keith A., Zhang, Yong-Jie, Baker, Matthew, Rademakers, Rosa, Petrucelli, Leonard, Dickson, Dennis W.
Publicado 2019

Loss of HDAC6, a novel CHIP substrate, alleviates abnormal tau accumulation

por Cook, Casey, Gendron, Tania F., Scheffel, Kristyn, Carlomagno, Yari, Dunmore, Judy, DeTure, Michael, Petrucelli, Leonard
Publicado 2012

Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expression

por Dickey, Chad A, Ash, Peter, Klosak, Natalia, Lee, Wing C, Petrucelli, Leonard, Hutton, Michael, Eckman, Christopher B
Publicado 2006

Phosphorylation regulates proteasomal-mediated degradation and solubility of TAR DNA binding protein-43 C-terminal fragments

por Zhang, Yong-Jie, Gendron, Tania F, Xu, Ya-Fei, Ko, Li-Wen, Yen, Shu-Hui, Petrucelli, Leonard
Publicado 2010

The Caenorhabditis elegans Ortholog of TDP-43 Regulates the Chromatin Localization of the Heterochromatin Protein 1 Homolog HPL-2

por Saldi, Tassa K., Gonzales, Patrick, Garrido-Lecca, Alfonso, Dostal, Vishantie, Roberts, Christine M., Petrucelli, Leonard, Link, Christopher D.
Publicado 2018