Expression of Functional Sphingosine-1 Phosphate Receptor-1 Is Reduced by B Cell Receptor Signaling and Increased by Inhibition of PI3 Kinase δ but Not SYK or BTK in Chronic Lympho...

por Till, Kathleen J., Pettitt, Andrew R., Slupsky, Joseph R.
Publicado 2015

Selective IAP inhibition results in sensitization of unstimulated but not CD40-stimulated chronic lymphocytic leukaemia cells to TRAIL-induced apoptosis

por Zhuang, Jianguo, Laing, Naomi, Oates, Melanie, Lin, Ke, Johnson, Gillian, Pettitt, Andrew R
Publicado 2014

Central nervous system plasmablastic lymphoma evolving from polyclonal plasmacytosis

por Khan, Umair T., Racu‐Amoasii, Igor, Arumainathan, Arvind, Meswani, Ushma, Pettitt, Andrew R., Menon, Geetha
Publicado 2018

Patient and health practitioner views and experiences of a cancer trial before and during COVID-19: qualitative study

por Sherratt, Frances C., Fisher, Peter, Mathieson, Amy, Cherry, Mary G., Pettitt, Andrew R., Young, Bridget
Publicado 2022

Immunohistochemical analysis indicates that the anatomical location of B-cell non-Hodgkin’s lymphoma is determined by differentially expressed chemokine receptors, sphingosine-1-ph...

por Middle, Stephen, Coupland, Sarah E, Taktak, Azzam, Kidgell, Victoria, Slupsky, Joseph R, Pettitt, Andrew R, Till, Kathleen J
Publicado 2015

Delineating the distinct role of AKT in mediating cell survival and proliferation induced by CD154 and IL-4/IL-21 in chronic lymphocytic leukemia

por Chapman, Elinor A., Oates, Melanie, Mohammad, Ishaque S., Davies, Barry R., Stockman, Paul K., Zhuang, Jianguo, Pettitt, Andrew R.
Publicado 2017

COVID‐19 outcomes in haematopoietic cell transplant recipients: A systematic review and meta‐analysis

por Lim, Yeong Jer, Khan, Umair, Karpha, Indrani, Ross, Andrew, Saif, Muhammad, Remberger, Mats, Kalakonda, Nagesh, Pettitt, Andrew R., Floisand, Yngvar
Publicado 2022

Roles of PI3Kγ and PI3Kδ in mantle cell lymphoma proliferation and migration contributing to efficacy of the PI3Kγ/δ inhibitor duvelisib

por Till, Kathleen J., Abdullah, Mariah, Alnassfan, Tahera, Janet, Gallardo Zapata, Marks, Thomas, Coma, Silvia, Weaver, David T., Pachter, Jonathan A., Pettitt, Andrew R., Slupsky, Joseph R.
Publicado 2023

Impact of idelalisib on health-related quality of life in patients with relapsed chronic lymphocytic leukemia in a phase III randomized trial

por Ghia, Paolo, Coutre, Steven E., Cheson, Bruce D., Barrientos, Jacqueline C., Hillmen, Peter, Pettitt, Andrew R., Zelenetz, Andrew D., Shreay, Sanatan, Hallek, Michael, Furman, Richard R.
Publicado 2020

Total Proteome Analysis Identifies Migration Defects as a Major Pathogenetic Factor in Immunoglobulin Heavy Chain Variable Region (IGHV)-unmutated Chronic Lymphocytic Leukemia

por Eagle, Gina L., Zhuang, Jianguo, Jenkins, Rosalind E., Till, Kathleen J., Jithesh, Puthen V., Lin, Ke, Johnson, Gillian G., Oates, Melanie, Park, Kevin, Kitteringham, Neil R., Pettitt, Andrew R.
Publicado 2015

Lck is a relevant target in chronic lymphocytic leukaemia cells whose expression variance is unrelated to disease outcome

por Till, Kathleen J., Allen, John C., Talab, Fatima, Lin, Ke, Allsup, David, Cawkwell, Lynn, Bentley, Alison, Ringshausen, Ingo, Duckworth, Andrew D., Pettitt, Andrew R., Kalakonda, Nagesh, Slupsky, Joseph R.
Publicado 2017

Assessing technical and biological variation in SWATH-MS-based proteomic analysis of chronic lymphocytic leukaemia cells

por Eagle, Gina L., Herbert, John M. J., Zhuang, Jianguo, Oates, Melanie, Khan, Umair T., Kitteringham, Neil R., Clarke, Kim, Park, B. Kevin, Pettitt, Andrew R., Jenkins, Rosalind E., Falciani, Francesco
Publicado 2021

The impact of complex karyotype on the overall survival of patients with relapsed chronic lymphocytic leukemia treated with idelalisib plus rituximab

por Kreuzer, Karl-Anton, Furman, Richard R., Stilgenbauer, Stephan, Dubowy, Ronald L., Kim, Yeonhee, Munugalavadla, Veerendra, Lilienweiss, Esther, Reinhardt, Hans Christian, Cramer, Paula, Eichhorst, Barbara, Hillmen, Peter, O’Brien, Susan M., Pettitt, Andrew R., Hallek, Michael
Publicado 2019

Kinobead Profiling Reveals Reprogramming of BCR Signaling in Response to Therapy within Primary CLL Cells

por Linley, Adam J., Karydis, Laura I., Mondru, Anil K., D'Avola, Annalisa, Al Shmrany, Humood, Cicconi, Silvia, Griffin, Rebecca, Forconi, Francesco, Pettitt, Andrew R., Kalakonda, Nagesh, Rawstron, Andrew C., Hillmen, Peter, Steele, Andrew J., MacEwan, David J., Packham, Graham, Prior, Ian A., Slupsky, Joseph R.
Publicado 2021

Evaluation of High-Throughput Genomic Assays for the Fc Gamma Receptor Locus

por Hargreaves, Chantal E., Iriyama, Chisako, Rose-Zerilli, Matthew J. J., Nagelkerke, Sietse Q., Hussain, Khiyam, Ganderton, Rosalind, Lee, Charlotte, Machado, Lee R., Hollox, Edward J., Parker, Helen, Latham, Kate V., Kuijpers, Taco W., Potter, Kathleen N., Coupland, Sarah E., Davies, Andrew, Stackpole, Michael, Oates, Melanie, Pettitt, Andrew R., Glennie, Martin J., Cragg, Mark S., Strefford, Jonathan C.
Publicado 2015

Correction: Evaluation of High-Throughput Genomic Assays for the Fc Gamma Receptor Locus

por Hargreaves, Chantal E., Iriyama, Chisako, Rose-Zerilli, Matthew J. J., Nagelkerke, Sietse Q., Hussain, Khiyam, Ganderton, Rosalind, Lee, Charlotte, Machado, Lee R., Hollox, Edward J., Parker, Helen, Latham, Kate V., Kuijpers, Taco W., Potter, Kathleen N., Coupland, Sarah E., Davies, Andrew, Stackpole, Michael, Oates, Melanie, Pettitt, Andrew R., Glennie, Martin J., Cragg, Mark S., Strefford, Jonathan C.
Publicado 2016

Lenalidomide, dexamethasone and alemtuzumab or ofatumumab in high-risk chronic lymphocytic leukemia: final results of the NCRI CLL210 trial

por Pettitt, Andrew R., Jackson, Richard, Cicconi, Silvia, Polydoros, Fotis, Yap, Christina, Dodd, James, Bickerstaff, Matthew, Stackpoole, Michael, Khan, Umair T., Carruthers, Stacey, Oates, Melanie, Lin, Ke, Coupland, Sarah E., Menon, Geetha, Kalakonda, Nagesh, McCarthy, Helen, Bloor, Adrian, Schuh, Anna, Duncombe, Andrew, Dearden, Claire, Fegan, Christopher, Kennedy, Ben, Walewska, Renata, Marshall, Scott, Fox, Christopher P., Hillmen, Peter
Publicado 2020

Final Results of a Randomized, Phase III Study of Rituximab With or Without Idelalisib Followed by Open-Label Idelalisib in Patients With Relapsed Chronic Lymphocytic Leukemia

por Sharman, Jeff P., Coutre, Steven E., Furman, Richard R., Cheson, Bruce D., Pagel, John M., Hillmen, Peter, Barrientos, Jacqueline C., Zelenetz, Andrew D., Kipps, Thomas J., Flinn, Ian W., Ghia, Paolo, Eradat, Herbert, Ervin, Thomas, Lamanna, Nicole, Coiffier, Bertrand, Pettitt, Andrew R., Ma, Shuo, Tausch, Eugen, Cramer, Paula, Huang, Julie, Mitra, Siddhartha, Hallek, Michael, O’Brien, Susan M., Stilgenbauer, Stephan
Publicado 2019

Common variants at 2q37.3, 8q24.21, 15q21.3, and 16q24.1 influence chronic lymphocytic leukemia risk

por Crowther-Swanepoel, Dalemari, Broderick, Peter, Di Bernardo, Maria Chiara, Dobbins, Sara E, Torres, María, Mansouri, Mahmoud, Ruiz-Ponte, Clara, Enjuanes, Anna, Rosenquist, Richard, Carracedo, Angel, Jurlander, Jesper, Campo, Elias, Juliusson, Gunnar, Montserrat, Emilio, Smedby, Karin E, Dyer, Martin JS, Matutes, Estella, Dearden, Claire, Sunter, Nicola J, Hall, Andrew G, Mainou-Fowler, Tryfonia, Jackson, Graham H, Summerfield, Geoffrey, Harris, Robert J, Pettitt, Andrew R, Allsup, David J, Bailey, James R, Pratt, Guy, Pepper, Chris, Fegan, Chris, Parker, Anton, Oscier, David, Allan, James M, Catovsky, Daniel, Houlston, Richard S
Publicado 2010

Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features

por Robbe, Pauline, Ridout, Kate E., Vavoulis, Dimitrios V., Dréau, Helene, Kinnersley, Ben, Denny, Nicholas, Chubb, Daniel, Appleby, Niamh, Cutts, Anthony, Cornish, Alex J., Lopez-Pascua, Laura, Clifford, Ruth, Burns, Adam, Stamatopoulos, Basile, Cabes, Maite, Alsolami, Reem, Antoniou, Pavlos, Oates, Melanie, Cavalieri, Doriane, Gibson, Jane, Prabhu, Anika V., Schwessinger, Ron, Jennings, Daisy, James, Terena, Maheswari, Uma, Duran-Ferrer, Martí, Carninci, Piero, Knight, Samantha J. L., Månsson, Robert, Hughes, Jim, Davies, James, Ross, Mark, Bentley, David, Strefford, Jonathan C., Devereux, Stephen, Pettitt, Andrew R., Hillmen, Peter, Caulfield, Mark J., Houlston, Richard S., Martín-Subero, José I., Schuh, Anna
Publicado 2022