IL-33 induces granzyme C expression in murine mast cells via an MSK1/2-CREB-dependent pathway

por Phair, Iain R., Sumoreeah, Megan C., Scott, Niamh, Spinelli, Laura, Arthur, J. Simon C.
Publicado 2022

Differential control of Toll-like receptor 4–induced interleukin-10 induction in macrophages and B cells reveals a role for p90 ribosomal S6 kinases

por Sutavani, Ruhcha V., Phair, Iain R., Barker, Rebecca, McFarlane, Alison, Shpiro, Natalia, Lang, Stuart, Woodland, Andrew, Arthur, J. Simon C.
Publicado 2018

AMPK integrates metabolite and kinase-based immunometabolic control in macrophages

por Phair, Iain R., Nisr, Raid B., Howden, Andrew J.M., Sovakova, Magdalena, Alqurashi, Noor, Foretz, Marc, Lamont, Douglas, Viollet, Benoit, Rena, Graham
Publicado 2022

IL‐33 regulates cytokine production and neutrophil recruitment via the p38 MAPK‐activated kinases MK2/3

por McCarthy, Pierre C, Phair, Iain R, Greger, Corinna, Pardali, Katerina, McGuire, Victoria A, Clark, Andrew R, Gaestel, Matthias, Arthur, J Simon C
Publicado 2018

DIA label-free proteomic analysis of murine bone-marrow-derived macrophages

por Baker, Christa P., Phair, Iain R., Brenes, Alejandro J., Atrih, Abdelmadjid, Ryan, Dylan G., Bruderer, Roland, Dinkova-Kostova, Albena T., Lamont, Douglas J., Arthur, J. Simon C., Howden, Andrew J.M.
Publicado 2022

Dimethyl fumarate blocks pro-inflammatory cytokine production via inhibition of TLR induced M1 and K63 ubiquitin chain formation

por McGuire, Victoria A., Ruiz-Zorrilla Diez, Tamara, Emmerich, Christoph H., Strickson, Sam, Ritorto, Maria Stella, Sutavani, Ruhcha V., Weiβ, Anne, Houslay, Kirsty F., Knebel, Axel, Meakin, Paul J., Phair, Iain R., Ashford, Michael L. J., Trost, Matthias, Arthur, J. Simon C.
Publicado 2016

Amino acid homeostasis is a target of metformin therapy

por Forteath, Calum, Mordi, Ify, Nisr, Raid, Gutierrez-Lara, Erika J., Alqurashi, Noor, Phair, Iain R., Cameron, Amy R., Beall, Craig, Bahr, Ibrahim, Mohan, Mohapradeep, Wong, Aaron K.F., Dihoum, Adel, Mohammad, Anwar, Palmer, Colin N.A., Lamont, Douglas, Sakamoto, Kei, Viollet, Benoit, Foretz, Marc, Lang, Chim C., Rena, Graham
Publicado 2023