dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region

por Levy, Shiri, Somasundaram, Logeshwaran, Raj, Infencia Xavier, Ic-Mex, Diego, Phal, Ashish, Schmidt, Sven, Ng, Weng I., Mar, Daniel, Decarreau, Justin, Moss, Nicholas, Alghadeer, Ammar, Honkanen, Henrik, Sarthy, Jay, Vitanza, Nicholas, Hawkins, R. David, Mathieu, Julie, Wang, Yuliang, Baker, David, Bomsztyk, Karol, Ruohola-Baker, Hannele
Publicado 2022

Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies

por Edman, Natasha I, Redler, Rachel L, Phal, Ashish, Schlichthaerle, Thomas, Srivatsan, Sanjay R, Etemadi, Ali, An, Seong J, Favor, Andrew, Ehnes, Devon, Li, Zhe, Praetorius, Florian, Gordon, Max, Yang, Wei, Coventry, Brian, Hicks, Derrick R., Cao, Longxing, Bethel, Neville, Heine, Piper, Murray, Analisa, Gerben, Stacey, Carter, Lauren, Miranda, Marcos, Negahdari, Babak, Lee, Sangwon, Trapnell, Cole, Stewart, Lance, Ekiert, Damian C., Schlessinger, Joseph, Shendure, Jay, Bhabha, Gira, Ruohola-Baker, Hannele, Baker, David
Publicado 2023

Design of protein-binding proteins from the target structure alone

por Cao, Longxing, Coventry, Brian, Goreshnik, Inna, Huang, Buwei, Sheffler, William, Park, Joon Sung, Jude, Kevin M., Marković, Iva, Kadam, Rameshwar U., Verschueren, Koen H. G., Verstraete, Kenneth, Walsh, Scott Thomas Russell, Bennett, Nathaniel, Phal, Ashish, Yang, Aerin, Kozodoy, Lisa, DeWitt, Michelle, Picton, Lora, Miller, Lauren, Strauch, Eva-Maria, DeBouver, Nicholas D., Pires, Allison, Bera, Asim K., Halabiya, Samer, Hammerson, Bradley, Yang, Wei, Bernard, Steffen, Stewart, Lance, Wilson, Ian A., Ruohola-Baker, Hannele, Schlessinger, Joseph, Lee, Sangwon, Savvides, Savvas N., Garcia, K. Christopher, Baker, David
Publicado 2022