A model of persistent post SARS-CoV-2 induced lung disease for target identification and testing of therapeutic strategies

por Dinnon, Kenneth H., Leist, Sarah R., Okuda, Kenichi, Dang, Hong, Fritch, Ethan J., Gully, Kendra L., De la Cruz, Gabriela, Evangelista, Mia D., Asakura, Takanori, Gilmore, Rodney C., Hawkins, Padraig, Nakano, Satoko, West, Ande, Schäfer, Alexandra, Gralinski, Lisa E., Everman, Jamie L., Sajuthi, Satria P., Zweigart, Mark R., Dong, Stephanie, McBride, Jennifer, Cooley, Michelle R., Hines, Jesse B., Love, Miriya K., Groshong, Steve D., VanSchoiack, Alison, Phelan, Stefan J., Liang, Yan, Hether, Tyler, Leon, Michael, Zumwalt, Ross E., Barton, Lisa M., Duval, Eric J., Mukhopadhyay, Sanjay, Stroberg, Edana, Borczuk, Alain, Thorne, Leigh B., Sakthivel, Muthu K., Lee, Yueh Z., Hagood, James S., Mock, Jason R., Seibold, Max A., O’Neal, Wanda K., Montgomery, Stephanie A., Boucher, Richard C., Baric, Ralph S.
Publicado 2022

SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in mice

por Dinnon, Kenneth H., Leist, Sarah R., Okuda, Kenichi, Dang, Hong, Fritch, Ethan J., Gully, Kendra L., De la Cruz, Gabriela, Evangelista, Mia D., Asakura, Takanori, Gilmore, Rodney C., Hawkins, Padraig, Nakano, Satoko, West, Ande, Schäfer, Alexandra, Gralinski, Lisa E., Everman, Jamie L., Sajuthi, Satria P., Zweigart, Mark R., Dong, Stephanie, McBride, Jennifer, Cooley, Michelle R., Hines, Jesse B., Love, Miriya K., Groshong, Steve D., VanSchoiack, Alison, Phelan, Stefan J., Liang, Yan, Hether, Tyler, Leon, Michael, Zumwalt, Ross E., Barton, Lisa M., Duval, Eric J., Mukhopadhyay, Sanjay, Stroberg, Edana, Borczuk, Alain, Thorne, Leigh B., Sakthivel, Muthu K., Lee, Yueh Z., Hagood, James S., Mock, Jason R., Seibold, Max A., O’Neal, Wanda K., Montgomery, Stephanie A., Boucher, Richard C., Baric, Ralph S.
Publicado 2022

A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients

por Pita-Juarez, Yered, Karagkouni, Dimitra, Kalavros, Nikolaos, Melms, Johannes C., Niezen, Sebastian, Delorey, Toni M., Essene, Adam L, Brook, Olga R., Pant, Deepti, Skelton-Badlani, Disha, Naderi, Pourya, Huang, Pinzhu, Pan, Liuliu, Hether, Tyler, Andrews, Tallulah S., Ziegler, Carly G.K., Reeves, Jason, Myloserdnyy, Andriy, Chen, Rachel, Nam, Andy, Phelan, Stefan, Liang, Yan, Amin, Amit Dipak, Biermann, Jana, Hibshoosh, Hanina, Veregge, Molly, Kramer, Zachary, Jacobs, Christopher, Yalcin, Yusuf, Phillips, Devan, Slyper, Michal, Subramanian, Ayshwarya, Ashenberg, Orr, Bloom-Ackermann, Zohar, Tran, Victoria M., Gomez, James, Sturm, Alexander, Zhang, Shuting, Fleming, Stephen J., Warren, Sarah, Beechem, Joseph, Hung, Deborah, Babadi, Mehrtash, Padera, Robert F., MacParland, Sonya A., Bader, Gary D., Imad, Nasser, Solomon, Isaac H., Miller, Eric, Riedel, Stefan, Porter, Caroline B.M., Villani, Alexandra-Chloé, Tsai, Linus T.-Y., Hide, Winston, Szabo, Gyongyi, Hecht, Jonathan, Rozenblatt-Rosen, Orit, Shalek, Alex K., Izar, Benjamin, Regev, Aviv, Popov, Yury, Jiang, Z. Gordon, Vlachos, Ioannis S.
Publicado 2022