Multiplexed CRISPR/CAS9‐mediated engineering of pre‐clinical mouse models bearing native human B cell receptors

por Wang, Xuesong, Ray, Rashmi, Kratochvil, Sven, Melzi, Eleonora, Lin, Ying‐Cing, Giguere, Sophie, Xu, Liling, Warner, John, Cheon, Diane, Liguori, Alessia, Groschel, Bettina, Phelps, Nicole, Adachi, Yumiko, Tingle, Ryan, Wu, Lin, Crotty, Shane, Kirsch, Kathrin H, Nair, Usha, Schief, William R, Batista, Facundo D
Publicado 2020

B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models

por Huang, Deli, Abbott, Robert K., Havenar-Daughton, Colin, Skog, Patrick D., Al-Kolla, Rita, Groschel, Bettina, Blane, Tanya R., Menis, Sergey, Tran, Jenny Tuyet, Thinnes, Theresa C., Volpi, Sabrina A., Liguori, Alessia, Schiffner, Torben, Villegas, Sophia M., Kalyuzhniy, Oleksandr, Pintea, Mark, Voss, James E., Phelps, Nicole, Tingle, Ryan, Rodriguez, Alberto R., Martin, Greg, Kupryianov, Sergey, deCamp, Allan, Schief, William R., Nemazee, David, Crotty, Shane
Publicado 2020

Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses

por Tas, Jeroen M.J., Koo, Ja-Hyun, Lin, Ying-Cing, Xie, Zhenfei, Steichen, Jon M., Jackson, Abigail M., Hauser, Blake M., Wang, Xuesong, Cottrell, Christopher A., Torres, Jonathan L., Warner, John E., Kirsch, Kathrin H., Weldon, Stephanie R., Groschel, Bettina, Nogal, Bartek, Ozorowski, Gabriel, Bangaru, Sandhya, Phelps, Nicole, Adachi, Yumiko, Eskandarzadeh, Saman, Kubitz, Michael, Burton, Dennis R., Lingwood, Daniel, Schmidt, Aaron G., Nair, Usha, Ward, Andrew B., Schief, William R., Batista, Facundo D.
Publicado 2022

Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors

por Willis, Jordan R., Berndsen, Zachary T., Ma, Krystal M., Steichen, Jon M., Schiffner, Torben, Landais, Elise, Liguori, Alessia, Kalyuzhniy, Oleksandr, Allen, Joel D., Baboo, Sabyasachi, Omorodion, Oluwarotimi, Diedrich, Jolene K., Hu, Xiaozhen, Georgeson, Erik, Phelps, Nicole, Eskandarzadeh, Saman, Groschel, Bettina, Kubitz, Michael, Adachi, Yumiko, Mullin, Tina-Marie, Alavi, Nushin B., Falcone, Samantha, Himansu, Sunny, Carfi, Andrea, Wilson, Ian A., Yates, John R., Paulson, James C., Crispin, Max, Ward, Andrew B., Schief, William R.
Publicado 2022