Cell death programs in Yersinia immunity and pathogenesis

por Philip, Naomi H., Brodsky, Igor E.
Publicado 2012

IQGAP1 Is Important for Activation of Caspase-1 in Macrophages and Is Targeted by Yersinia pestis Type III Effector YopM

por Chung, Lawton K., Philip, Naomi H., Schmidt, Valentina A., Koller, Antonius, Strowig, Till, Flavell, Richard A., Brodsky, Igor E., Bliska, James B.
Publicado 2014

Inflammasome Activation in Response to the Yersinia Type III Secretion System Requires Hyperinjection of Translocon Proteins YopB and YopD

por Zwack, Erin E., Snyder, Annelise G., Wynosky-Dolfi, Meghan A., Ruthel, Gordon, Philip, Naomi H., Marketon, Melanie M., Francis, Matthew S., Bliska, James B., Brodsky, Igor E.
Publicado 2015

Microenvironmental sensing by fibroblasts controls macrophage population size

por Zhou, Xu, Franklin, Ruth A., Adler, Miri, Carter, Trevor S., Condiff, Emily, Adams, Taylor S., Pope, Scott D., Philip, Naomi H., Meizlish, Matthew L., Kaminski, Naftali, Medzhitov, Ruslan
Publicado 2022

T cells instruct myeloid cells to produce inflammasome-independent IL-1β and cause autoimmunity

por Jain, Aakanksha, Irizarry-Caro, Ricardo A., McDaniel, Margaret M., Chawla, Amanpreet Singh, Carroll, Kaitlin R., Overcast, Garrett R., Philip, Naomi H., Oberst, Andrew, Chervonsky, Alexander V., Katz, Jonathan D., Pasare, Chandrashekhar
Publicado 2019

Oxidative metabolism enables Salmonella evasion of the NLRP3 inflammasome

por Wynosky-Dolfi, Meghan A., Snyder, Annelise G., Philip, Naomi H., Doonan, Patrick J., Poffenberger, Maya C., Avizonis, Daina, Zwack, Erin E., Riblett, Amber M., Hu, Baofeng, Strowig, Till, Flavell, Richard A., Jones, Russell G., Freedman, Bruce D., Brodsky, Igor E.
Publicado 2014

RIPK1-dependent apoptosis bypasses pathogen blockade of innate signaling to promote immune defense

por Peterson, Lance W., Philip, Naomi H., DeLaney, Alexandra, Wynosky-Dolfi, Meghan A., Asklof, Kendra, Gray, Falon, Choa, Ruth, Bjanes, Elisabet, Buza, Elisabeth L., Hu, Baofeng, Dillon, Christopher P., Green, Douglas R., Berger, Scott B., Gough, Peter J., Bertin, John, Brodsky, Igor E.
Publicado 2017

Leukocyte dynamics after intracerebral hemorrhage in a living patient reveal rapid adaptations to tissue milieu

por Goods, Brittany A., Askenase, Michael H., Markarian, Erica, Beatty, Hannah E., Drake, Riley S., Fleming, Ira, DeLong, Jonathan H., Philip, Naomi H., Matouk, Charles C., Awad, Issam A., Zuccarello, Mario, Hanley, Daniel F., Love, J. Christopher, Shalek, Alex K., Sansing, Lauren H.
Publicado 2021

Activity of Uncleaved Caspase-8 Controls Anti-bacterial Immune Defense and TLR-Induced Cytokine Production Independent of Cell Death

por Philip, Naomi H., DeLaney, Alexandra, Peterson, Lance W., Santos-Marrero, Melanie, Grier, Jennifer T., Sun, Yan, Wynosky-Dolfi, Meghan A., Zwack, Erin E., Hu, Baofeng, Olsen, Tayla M., Rongvaux, Anthony, Pope, Scott D., López, Carolina B., Oberst, Andrew, Beiting, Daniel P., Henao-Mejia, Jorge, Brodsky, Igor E.
Publicado 2016

Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection

por Bjanes, Elisabet, Sillas, Reyna Garcia, Matsuda, Rina, Demarco, Benjamin, Fettrelet, Timothée, DeLaney, Alexandra A., Kornfeld, Opher S., Lee, Bettina L., Rodríguez López, Eric M., Grubaugh, Daniel, Wynosky-Dolfi, Meghan A., Philip, Naomi H., Krespan, Elise, Tovar, Dorothy, Joannas, Leonel, Beiting, Daniel P., Henao-Mejia, Jorge, Schaefer, Brian C., Chen, Kaiwen W., Broz, Petr, Brodsky, Igor E.
Publicado 2021