Dynamics and variability in the pleiotropic effects of adaptation in laboratory budding yeast populations

por Bakerlee, Christopher W, Phillips, Angela M, Nguyen Ba, Alex N, Desai, Michael M
Publicado 2021

The genetic basis of differential autodiploidization in evolving yeast populations

por Tung, Sudipta, Bakerlee, Christopher W, Phillips, Angela M, Nguyen Ba, Alex N, Desai, Michael M
Publicado 2021

Hierarchical sequence-affinity landscapes shape the evolution of breadth in an anti-influenza receptor binding site antibody

por Phillips, Angela M, Maurer, Daniel P, Brooks, Caelan, Dupic, Thomas, Schmidt, Aaron G, Desai, Michael M
Publicado 2023

Quantifying Drosophila food intake: comparative analysis of current methodology

por Deshpande, Sonali A., Carvalho, Gil B., Amador, Ariadna, Phillips, Angela M., Hoxha, Sany, Lizotte, Keith J., Ja, William W.
Publicado 2014

Enhanced ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin

por Phillips, Angela M, Doud, Michael B, Gonzalez, Luna O, Butty, Vincent L, Lin, Yu-Shan, Bloom, Jesse D, Shoulders, Matthew D
Publicado 2018

Binding affinity landscapes constrain the evolution of broadly neutralizing anti-influenza antibodies

por Phillips, Angela M, Lawrence, Katherine R, Moulana, Alief, Dupic, Thomas, Chang, Jeffrey, Johnson, Milo S, Cvijovic, Ivana, Mora, Thierry, Walczak, Aleksandra M, Desai, Michael M
Publicado 2021

The landscape of antibody binding affinity in SARS-CoV-2 Omicron BA.1 evolution

por Moulana, Alief, Dupic, Thomas, Phillips, Angela M, Chang, Jeffrey, Roffler, Anne A, Greaney, Allison J, Starr, Tyler N, Bloom, Jesse D, Desai, Michael M
Publicado 2023

Compensatory epistasis maintains ACE2 affinity in SARS-CoV-2 Omicron BA.1

por Moulana, Alief, Dupic, Thomas, Phillips, Angela M., Chang, Jeffrey, Nieves, Serafina, Roffler, Anne A., Greaney, Allison J., Starr, Tyler N., Bloom, Jesse D., Desai, Michael M.
Publicado 2022

Host proteostasis modulates influenza evolution

por Phillips, Angela M, Gonzalez, Luna O, Nekongo, Emmanuel E, Ponomarenko, Anna I, McHugh, Sean M, Butty, Vincent L, Levine, Stuart S, Lin, Yu-Shan, Mirny, Leonid A, Shoulders, Matthew D
Publicado 2017

Destabilized adaptive influenza variants critical for innate immune system escape are potentiated by host chaperones

por Phillips, Angela M., Ponomarenko, Anna I., Chen, Kenny, Ashenberg, Orr, Miao, Jiayuan, McHugh, Sean M., Butty, Vincent L., Whittaker, Charles A., Moore, Christopher L., Bloom, Jesse D., Lin, Yu-Shan, Shoulders, Matthew D.
Publicado 2018

The endoplasmic reticulum proteostasis network profoundly shapes the protein sequence space accessible to HIV envelope

por Yoon, Jimin, Nekongo, Emmanuel E., Patrick, Jessica E., Hui, Tiffani, Phillips, Angela M., Ponomarenko, Anna I., Hendel, Samuel J., Sebastian, Rebecca M., Zhang, Yu Meng, Butty, Vincent L., Ogbunugafor, C. Brandon, Lin, Yu-Shan, Shoulders, Matthew D.
Publicado 2022

Phenotypic and molecular evolution across 10,000 generations in laboratory budding yeast populations

por Johnson, Milo S, Gopalakrishnan, Shreyas, Goyal, Juhee, Dillingham, Megan E, Bakerlee, Christopher W, Humphrey, Parris T, Jagdish, Tanush, Jerison, Elizabeth R, Kosheleva, Katya, Lawrence, Katherine R, Min, Jiseon, Moulana, Alief, Phillips, Angela M, Piper, Julia C, Purkanti, Ramya, Rego-Costa, Artur, McDonald, Michael J, Nguyen Ba, Alex N, Desai, Michael M
Publicado 2021