Membrane Sensor Histidine Kinases: Insights from Structural, Ligand and Inhibitor Studies of Full-Length Proteins and Signalling Domains for Antibiotic Discovery

por Ma, Pikyee, Phillips-Jones, Mary K.
Publicado 2021

Antimicrobial resistance (AMR) nanomachines—mechanisms for fluoroquinolone and glycopeptide recognition, efflux and/or deactivation

por Phillips-Jones, Mary K., Harding, Stephen E.
Publicado 2018

The discovery of hydrogen bonds in DNA and a re-evaluation of the 1948 Creeth two-chain model for its structure

por Harding, Stephen E., Channell, Guy, Phillips-Jones, Mary K.
Publicado 2018

Structure of the response regulator VicR DNA-binding domain

por Trinh, Chi-Hung, Liu, Yang, Phillips, Simon E. V., Phillips-Jones, Mary K.
Publicado 2007

Hydrodynamic Compatibility of Hyaluronic Acid and Tamarind Seed Polysaccharide as Ocular Mucin Supplements

por Chun, Taewoo, MacCalman, Thomas, Dinu, Vlad, Ottino, Sara, Phillips-Jones, Mary K., Harding, Stephen E.
Publicado 2020

The gelatinase biosynthesis‐activating pheromone binds and stabilises the FsrB membrane protein in Enterococcus faecalis quorum sensing

por Littlewood, Sean, Tattersall, Helena, Hughes, Charlotte S., Hussain, Rohanah, Ma, Pikyee, Harding, Stephen E., Nakayama, Jiro, Phillips‐Jones, Mary K.
Publicado 2019

Full hydrodynamic reversibility of the weak dimerization of vancomycin and elucidation of its interaction with VanS monomers at clinical concentration

por Phillips-Jones, Mary K., Lithgo, Ryan, Dinu, Vlad, Gillis, Richard B., Harding, John E., Adams, Gary G., Harding, Stephen E.
Publicado 2017

Characterisation of mass distributions of solvent-fractionated lignins using analytical ultracentrifugation and size exclusion chromatography methods

por Lu, Yudong, Joosten, Lionard, Donkers, Jacqueline, Andriulo, Fabrizio, Slaghek, Ted M., Phillips-Jones, Mary K., Gosselink, Richard J. A., Harding, Stephen E.
Publicado 2021

Purification of bacterial membrane sensor kinases and biophysical methods for determination of their ligand and inhibitor interactions

por Hussain, Rohanah, Harding, Stephen E., Hughes, Charlotte S., Ma, Pikyee, Patching, Simon G., Edara, Shalini, Siligardi, Giuliano, Henderson, Peter J.F., Phillips-Jones, Mary K.
Publicado 2016

Hydrodynamics of the VanA-type VanS histidine kinase: an extended solution conformation and first evidence for interactions with vancomycin

por Phillips-Jones, Mary K., Channell, Guy, Kelsall, Claire J., Hughes, Charlotte S., Ashcroft, Alison E., Patching, Simon G., Dinu, Vlad, Gillis, Richard B., Adams, Gary G., Harding, Stephen E.
Publicado 2017

The antibiotic vancomycin induces complexation and aggregation of gastrointestinal and submaxillary mucins

por Dinu, Vlad, Lu, Yudong, Weston, Nicola, Lithgo, Ryan, Coupe, Hayley, Channell, Guy, Adams, Gary G., Torcello Gómez, Amelia, Sabater, Carlos, Mackie, Alan, Parmenter, Christopher, Fisk, Ian, Phillips-Jones, Mary K., Harding, Stephen E.
Publicado 2020

Production of membrane proteins for characterisation of their pheromone-sensing and antimicrobial resistance functions

por Azam, Aalishaa A., Kinder, Jean M., Khan, G. Nasir, Alase, Ade, Ma, Pikyee, Liu, Yang, Ault, James R., Henderson, Peter J. F., Chowdhry, Babur Z., Alexander, Bruce D., Harding, Stephen E., Phillips-Jones, Mary K.
Publicado 2018