Defining tumor-associated vascular heterogeneity in pediatric high-grade and diffuse midline gliomas

por Wei, Xin, Meel, Michaël H., Breur, Marjolein, Bugiani, Marianna, Hulleman, Esther, Phoenix, Timothy N.
Publicado 2021

DIPG-22. DISSECTING THE ONCOGENIC ROLE OF FOXR2 IN DIFFUSE INTRINSIC PONTINE GLIOMA

por Tsai, Jessica W, Patel, Smruti K, Bear, Heather, Dubois, Frank, Khadka, Prasidda, Lu, Sophie, Gonzalez, Elizabeth, Ligon, Keith, Bandopadhayay, Pratiti, Phoenix, Timothy N
Publicado 2020

Molecular Characterisation of Transport Mechanisms at the Developing Mouse Blood–CSF Interface: A Transcriptome Approach

por Liddelow, Shane A., Temple, Sally, Møllgård, Kjeld, Gehwolf, Renate, Wagner, Andrea, Bauer, Hannelore, Bauer, Hans-Christian, Phoenix, Timothy N., Dziegielewska, Katarzyna M., Saunders, Norman R.
Publicado 2012

Correction: Molecular Characterisation of Transport Mechanisms at the Developing Mouse Blood–CSF Interface: A Transcriptome Approach

por Liddelow, Shane A., Temple, Sally, Møllgård, Kjeld, Gehwolf, Renate, Wagner, Andrea, Bauer, Hannelore, Bauer, Hans-Christian, Phoenix, Timothy N., Dziegielewska, Katarzyna M., Saunders, Norman R.
Publicado 2012

Generation of immunocompetent syngeneic allograft mouse models for pediatric diffuse midline glioma

por du Chatinier, Aimée, Meel, Michaël H, Das, Arvid I, Metselaar, Dennis S, Waranecki, Piotr, Bugiani, Marianna, Breur, Marjolein, Simonds, Erin F, Lu, Edbert D, Weiss, William A, Garcia Vallejo, Juan J, Hoving, Eelco W, Phoenix, Timothy N, Hulleman, Esther
Publicado 2022

MEK/MELK inhibition and blood–brain barrier deficiencies in atypical teratoid/rhabdoid tumors

por Meel, Michaël H, Guillén Navarro, Miriam, de Gooijer, Mark C, Metselaar, Dennis S, Waranecki, Piotr, Breur, Marjolein, Lagerweij, Tonny, Wedekind, Laurine E, Koster, Jan, van de Wetering, Marianne D, Schouten-van Meeteren, Netteke, Aronica, Eleonora, van Tellingen, Olaf, Bugiani, Marianna, Phoenix, Timothy N, Kaspers, Gertjan J L, Hulleman, Esther
Publicado 2020

Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma

por Hofman, Damon A., Ruiz-Orera, Jorge, Yannuzzi, Ian, Murugesan, Rakesh, Brown, Adam, Clauser, Karl R., Condurat, Alexandra L., van Dinter, Jip T., Engels, Sem A.G., Goodale, Amy, van der Lugt, Jasper, Abid, Tanaz, Wang, Li, Zhou, Kevin N., Vogelzang, Jayne, Ligon, Keith L., Phoenix, Timothy N., Roth, Jennifer A., Root, David E., Hubner, Norbert, Golub, Todd R., Bandopadhayay, Pratiti, van Heesch, Sebastiaan, Prensner, John R.
Publicado 2023

TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory

por Ausejo-Mauleon, Iker, Labiano, Sara, de la Nava, Daniel, Laspidea, Virginia, Zalacain, Marta, Marrodán, Lucía, García-Moure, Marc, González-Huarriz, Marisol, Hervás-Corpión, Irati, Dhandapani, Laasya, Vicent, Silvestre, Collantes, Maria, Peñuelas, Iván, Becher, Oren J., Filbin, Mariella G., Jiang, Li, Labelle, Jenna, de Biagi-Junior, Carlos A.O., Nazarian, Javad, Laternser, Sandra, Phoenix, Timothy N., van der Lugt, Jasper, Kranendonk, Mariette, Hoogendijk, Raoull, Mueller, Sabine, De Andrea, Carlos, Anderson, Ana C., Guruceaga, Elizabeth, Koschmann, Carl, Yadav, Viveka Nand, Gállego Pérez-Larraya, Jaime, Patiño-García, Ana, Pastor, Fernando, Alonso, Marta M.
Publicado 2023

C11orf95-RELA fusions drive oncogenic NF-κB signaling in ependymoma

por Parker, Matthew, Mohankumar, Kumarasamypet M., Punchihewa, Chandanamali, Weinlich, Ricardo, Dalton, James D., Li, Yongjin, Lee, Ryan, Tatevossian, Ruth G., Phoenix, Timothy N., Thiruvenkatam, Radhika, White, Elsie, Tang, Bo, Orisme, Wilda, Gupta, Kirti, Rusch, Michael, Chen, Xiang, Li, Yuxin, Nagahawhatte, Panduka, Hedlund, Erin, Finkelstein, David, Wu, Gang, Shurtleff, Sheila, Easton, John, Boggs, Kristy, Yergeau, Donald, Vadodaria, Bhavin, Mulder, Heather L, Becksford, Jared, Gupta, Pankaj, Huether, Robert, Ma, Jing, Song, Guangchun, Gajjar, Amar, Merchant, Thomas, Boop, Frederick, Smith, Amy A, Ding, Li, Lu, Charles, Ochoa, Kerri, Zhao, David, Fulton, Robert S, Fulton, Lucinda L, Mardis, Elaine R., Wilson, Richard K., Downing, James R., Green, Douglas R., Zhang, Jinghui, Ellison, David W., Gilbertson, Richard J.
Publicado 2014

Novel mutations target distinct subgroups of medulloblastoma

por Robinson, Giles, Parker, Matthew, Kranenburg, Tanya A., Lu, Charles, Chen, Xiang, Ding, Li, Phoenix, Timothy N., Hedlund, Erin, Wei, Lei, Zhu, Xiaoyan, Chalhoub, Nader, Baker, Suzanne J., Huether, Robert, Kriwacki, Richard, Curley, Natasha, Thiruvenkatam, Radhika, Wang, Jianmin, Wu, Gang, Rusch, Michael, Hong, Xin, Beckford, Jared, Gupta, Pankaj, Ma, Jing, Easton, John, Vadodaria, Bhavin, Onar-Thomas, Arzu, Lin, Tong, Li, Shaoyi, Pounds, Stanley, Paugh, Steven, Zhao, David, Kawauchi, Daisuke, Roussel, Martine F., Finkelstein, David, Ellison, David W., Lau, Ching C., Bouffet, Eric, Hassall, Tim, Gururangan, Sridharan, Cohn, Richard, Fulton, Robert S., Fulton, Lucinda L., Dooling, David J., Ochoa, Kerri, Gajjar, Amar, Mardis, Elaine R., Wilson, Richard K., Downing, James R., Zhang, Jinghui, Gilbertson, Richard J.
Publicado 2012

DIPG-19. FOXR2 is an oncogenic driver across pediatric and adult cancers

por Tsai, Jessica W, Cejas, Paloma, Wang, Dayle K, Patel, Smruti, Wu, David W, Arounleut, Phonepasong, Wei, Xin, Zhou, Ningxuan, Syamala, Sudeepa, Dubois, Frank P B, Crane, Alexander, Pelton, Kristine, Vogelzang, Jayne, Sousa, Cecilia, Baguette, Audrey, Chen, Xiaolong, Condurat, Alexandra L, Dixon-Clarke, Sarah E, Zhou, Kevin N, Lu, Sophie D, Gonzalez, Elizabeth M, Chacon, Madison S, Digiacomo, Jeromy J, Kumbhani, Rushil, Novikov, Dana, Hunter, J'Ya, Tsoli, Maria, Ziegler, David S, Dirksen, Uta, Jager, Natalie, Balasubramanian, Gnana Prakash, Kramm, Christof M, Nathrath, Michaela, Bielack, Stefan, Baker, Suzanne J, Zhang, Jinghui, McFarland, James M, Getz, Gad, Aguet, Francois, Jabado, Nada, Witt, Olaf, Pfister, Stefan M, Ligon, Keith L, Kleinman, Claudia L, Long, Henry, Jones, David T W, Bandopadhayay, Pratiti, Phoenix, Timothy N
Publicado 2022

FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits

por Tsai, Jessica W., Cejas, Paloma, Wang, Dayle K., Patel, Smruti, Wu, David W., Arounleut, Phonepasong, Wei, Xin, Zhou, Ningxuan, Syamala, Sudeepa, Dubois, Frank P.B., Crane, Alexander, Pelton, Kristine, Vogelzang, Jayne, Sousa, Cecilia, Baguette, Audrey, Chen, Xiaolong, Condurat, Alexandra L., Dixon-Clarke, Sarah E., Zhou, Kevin N., Lu, Sophie D., Gonzalez, Elizabeth M., Chacon, Madison S., Digiacomo, Jeromy J., Kumbhani, Rushil, Novikov, Dana, Hunter, J'Ya, Tsoli, Maria, Ziegler, David S., Dirksen, Uta, Jager, Natalie, Balasubramanian, Gnana Prakash, Kramm, Christof M., Nathrath, Michaela, Bielack, Stefan, Baker, Suzanne J., Zhang, Jinghui, McFarland, James M., Getz, Gad, Aguet, François, Jabado, Nada, Witt, Olaf, Pfister, Stefan M., Ligon, Keith L., Hovestadt, Volker, Kleinman, Claudia L., Long, Henry, Jones, David T.W., Bandopadhayay, Pratiti, Phoenix, Timothy N.
Publicado 2022

Resolving medulloblastoma cellular architecture by single-cell genomics

por Hovestadt, Volker, Smith, Kyle S., Bihannic, Laure, Filbin, Mariella G., Shaw, McKenzie L., Baumgartner, Alicia, DeWitt, John C., Groves, Andrew, Mayr, Lisa, Weisman, Hannah R., Richman, Alyssa R., Shore, Marni E., Goumnerova, Liliana, Rosencrance, Celeste, Carter, Robert A., Phoenix, Timothy N., Hadley, Jennifer L., Tong, Yiai, Houston, Jim, Ashmun, Richard A., DeCuypere, Michael, Sharma, Tanvi, Flasch, Diane, Silkov, Antonina, Ligon, Keith, Pomeroy, Scott L., Rivera, Miguel N., Rozenblatt-Rosen, Orit, Rusert, Jessica M., Wechsler-Reya, Robert J., Li, Xiao-Nan, Peyrl, Andreas, Gojo, Johannes, Kirchhofer, Dominik, Lötsch, Daniela, Czech, Thomas, Dorfer, Christian, Haberler, Christine, Geyeregger, Rene, Halfmann, Angela, Gawad, Charles, Easton, John, Pfister, Stefan M., Regev, Aviv, Gajjar, Amar, Orr, Brent A., Slavc, Irene, Robinson, Giles W., Bernstein, Bradley E., Suvà, Mario L., Northcott, Paul A.
Publicado 2019

PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation

por Khadka, Prasidda, Reitman, Zachary J., Lu, Sophie, Buchan, Graham, Gionet, Gabrielle, Dubois, Frank, Carvalho, Diana M., Shih, Juliann, Zhang, Shu, Greenwald, Noah F., Zack, Travis, Shapira, Ofer, Pelton, Kristine, Hartley, Rachel, Bear, Heather, Georgis, Yohanna, Jarmale, Spandana, Melanson, Randy, Bonanno, Kevin, Schoolcraft, Kathleen, Miller, Peter G., Condurat, Alexandra L., Gonzalez, Elizabeth M., Qian, Kenin, Morin, Eric, Langhnoja, Jaldeep, Lupien, Leslie E., Rendo, Veronica, Digiacomo, Jeromy, Wang, Dayle, Zhou, Kevin, Kumbhani, Rushil, Guerra Garcia, Maria E., Sinai, Claire E., Becker, Sarah, Schneider, Rachel, Vogelzang, Jayne, Krug, Karsten, Goodale, Amy, Abid, Tanaz, Kalani, Zohra, Piccioni, Federica, Beroukhim, Rameen, Persky, Nicole S., Root, David E., Carcaboso, Angel M., Ebert, Benjamin L., Fuller, Christine, Babur, Ozgun, Kieran, Mark W., Jones, Chris, Keshishian, Hasmik, Ligon, Keith L., Carr, Steven A., Phoenix, Timothy N., Bandopadhayay, Pratiti
Publicado 2022