COX-Independent Mechanisms of Cancer Chemoprevention by Anti-Inflammatory Drugs

por Gurpinar, Evrim, Grizzle, William E., Piazza, Gary A.
Publicado 2013

Editorial: Targeting the Wnt/β-catenin signaling pathway in cancer

por Patergnani, Simone, Buchsbaum, Donald J., Piazza, Gary A.
Publicado 2022

The Role of Cyclic Nucleotide Signaling Pathways in Cancer: Targets for Prevention and Treatment

por Fajardo, Alexandra M., Piazza, Gary A., Tinsley, Heather N.
Publicado 2014

Hypoxia-regulated microRNAs in human cancer

por Shen, Guomin, Li, Xiaobo, Jia, Yong-feng, Piazza, Gary A, Xi, Yaguang
Publicado 2013

The path to the clinic: a comprehensive review on direct KRAS(G12C) inhibitors

por Kwan, Albert K., Piazza, Gary A., Keeton, Adam B., Leite, Caio A.
Publicado 2022

Synthesis, Molecular Modeling, and Biological Evaluation of Novel Tetrahydro-β-Carboline Hydantoin and Tetrahydro-β-Carboline Thiohydantoin Derivatives as Phosphodiesterase 5 Inhib...

por Abadi, Ashraf H., Lehmann, Jochen, Piazza, Gary A., Abdel-Halim, Mohammad, Ali, Mohamed S. M.
Publicado 2011

Exploiting RAS Nucleotide Cycling as a Strategy for Drugging RAS-Driven Cancers

por Mattox, Tyler E., Chen, Xi, Maxuitenko, Yulia Y., Keeton, Adam B., Piazza, Gary A.
Publicado 2019

Niclosamide Suppresses Cancer Cell Growth By Inducing Wnt Co-Receptor LRP6 Degradation and Inhibiting the Wnt/β-Catenin Pathway

por Lu, Wenyan, Lin, Cuihong, Roberts, Michael J., Waud, William R., Piazza, Gary A., Li, Yonghe
Publicado 2011

Inhibition of breast cancer cell motility with a non-cyclooxygenase inhibitory derivative of sulindac by suppressing TGFβ/miR-21 signaling

por Yi, Bin, Chang, Hong, Ma, Ruixia, Feng, Xiangling, Li, Wei, Piazza, Gary A., Xi, Yaguang
Publicado 2016

Antiproliferative activity and possible mechanism of action of certain 5-methoxyindole tethered C-5 functionalized isatins

por Almutairi, Maha S, Hassan, Eman S, Keeton, Adam B, Piazza, Gary A, Abdelhameed, Ali S, Attia, Mohamed I
Publicado 2019

β-catenin nuclear translocation in colorectal cancer cells is suppressed by PDE10A inhibition, cGMP elevation, and activation of PKG

por Lee, Kevin, Lindsey, Ashley S., Li, Nan, Gary, Bernard, Andrews, Joel, Keeton, Adam B., Piazza, Gary A.
Publicado 2015

New Isatin–Indole Conjugates: Synthesis, Characterization, and a Plausible Mechanism of Their in vitro Antiproliferative Activity

por Al-Wabli, Reem I, Almomen, Aliyah A, Almutairi, Maha S, Keeton, Adam B, Piazza, Gary A, Attia, Mohamed I
Publicado 2020

Structure-Based Design of Novel Tetrahydro-Beta-Carboline Derivatives with a Hydrophilic Side Chain as Potential Phosphodiesterase Inhibitors

por Elhady, Ahmed K., Sigler, Sara C., Noureldin, Nazih, Canzoneri, Joshua C., Ahmed, Nermin S., Piazza, Gary A., Abadi, Ashraf H.
Publicado 2015

New hydrazonoindolin-2-ones: Synthesis, exploration of the possible anti-proliferative mechanism of action and encapsulation into PLGA microspheres

por Attia, Mohamed I., Eldehna, Wagdy M., Afifi, Samar A., Keeton, Adam B., Piazza, Gary A., Abdel-Aziz, Hatem A.
Publicado 2017

Sulindac sulfide selectively increases sensitivity of ABCC1 expressing tumor cells to doxorubicin and glutathione depletion

por Whitt, Jason D., Keeton, Adam B., Gary, Bernard D., Sklar, Larry A., Sodani, Kamlesh, Chen, Zhe-Sheng, Piazza, Gary A.
Publicado 2016

Synthesis and biological evaluation of certain hydrazonoindolin-2-one derivatives as new potent anti-proliferative agents

por Eldehna, Wagdy M., Al-Wabli, Reem I., Almutairi, Maha S., Keeton, Adam B., Piazza, Gary A., Abdel-Aziz, Hatem A., Attia, Mohamed I.
Publicado 2018

Allyl isothiocyanate induces replication-associated DNA damage response in NSCLC cells and sensitizes to ionizing radiation

por Tripathi, Kaushlendra, Hussein, Usama K., Anupalli, Roja, Barnett, Reagan, Bachaboina, Lavanya, Scalici, Jennifer, Rocconi, Rodney P., Owen, Laurie B., Piazza, Gary A., Palle, Komaraiah
Publicado 2015

Isatin-benzoazine molecular hybrids as potential antiproliferative agents: synthesis and in vitro pharmacological profiling

por Abdel-Aziz, Hatem A, Eldehna, Wagdy M, Keeton, Adam B, Piazza, Gary A, Kadi, Adnan A, Attwa, Mohamed W, Abdelhameed, Ali S, Attia, Mohamed I
Publicado 2017

NSAIDs: Old Drugs Reveal New Anticancer Targets

por Piazza, Gary A., Keeton, Adam B., Tinsley, Heather N., Whitt, Jason D., Gary, Bernard D., Mathew, Bini, Singh, Raj, Grizzle, William E., Reynolds, Robert C.
Publicado 2010

Panepoxydone Targets NF-kB and FOXM1 to Inhibit Proliferation, Induce Apoptosis and Reverse Epithelial to Mesenchymal Transition in Breast Cancer

por Arora, Ritu, Yates, Clayton, Gary, Bernard D., McClellan, Steven, Tan, Ming, Xi, Yaguang, Reed, Eddie, Piazza, Gary A., Owen, Laurie B., Dean-Colomb, Windy
Publicado 2014