The cell-specific activity of the estrogen receptor α may be fine-tuned by phosphorylation-induced structural gymnastics

por Gburcik, Valentina, Picard, Didier
Publicado 2006

Genomics of Signaling Crosstalk of Estrogen Receptor α in Breast Cancer Cells

por Dudek, Peter, Picard, Didier
Publicado 2008

Secreted dual reporter assay with Gaussia luciferase and the red fluorescent protein mCherry

por Wider, Diana, Picard, Didier
Publicado 2017

The Hsp70–Hsp90 go-between Hop/Stip1/Sti1 is a proteostatic switch and may be a drug target in cancer and neurodegeneration

por Bhattacharya, Kaushik, Picard, Didier
Publicado 2021

Cytosolic Hsp90 Isoform-Specific Functions and Clinical Significance

por Maiti, Samarpan, Picard, Didier
Publicado 2022

CRISPR-Cas9 screen reveals a role of purine synthesis for estrogen receptor α activity and tamoxifen resistance of breast cancer cells

por Hany, Dina, Vafeiadou, Vasiliki, Picard, Didier
Publicado 2023

Luminescence resonance energy transfer between genetically encoded donor and acceptor for protein-protein interaction studies in the molecular chaperone HSP70/HSP90 complexes

por Bhattacharya, Kaushik, Bernasconi, Lilia, Picard, Didier
Publicado 2018

Hyperactivation of MAPK Induces Tamoxifen Resistance in SPRED2-Deficient ERα-Positive Breast Cancer

por Vafeiadou, Vasiliki, Hany, Dina, Picard, Didier
Publicado 2022

Proteomic Analyses of the G Protein-Coupled Estrogen Receptor GPER1 Reveal Constitutive Links to Endoplasmic Reticulum, Glycosylation, Trafficking, and Calcium Signaling

por Ahmadian Elmi, Maryam, Motamed, Nasrin, Picard, Didier
Publicado 2023

ERα activity depends on interaction and target site corecruitment with phosphorylated CREB1

por Berto, Melissa, Jean, Valerie, Zwart, Wilbert, Picard, Didier
Publicado 2018

The Mitochondrial HSP90 Paralog TRAP1: Structural Dynamics, Interactome, Role in Metabolic Regulation, and Inhibitors

por Joshi, Abhinav, Ito, Takeshi, Picard, Didier, Neckers, Len
Publicado 2022

LSD1 engages a corepressor complex for the activation of the estrogen receptor α by estrogen and cAMP

por Bennesch, Marcela A., Segala, Gregory, Wider, Diana, Picard, Didier
Publicado 2016

Network-informed discovery of multidrug combinations for ERα+/HER2-/PI3Kα-mutant breast cancer

por Hany, Dina, Zoetemelk, Marloes, Bhattacharya, Kaushik, Nowak-Sliwinska, Patrycja, Picard, Didier
Publicado 2023

An Interaction Network Predicted from Public Data as a Discovery Tool: Application to the Hsp90 Molecular Chaperone Machine

por Echeverría, Pablo C., Bernthaler, Andreas, Dupuis, Pierre, Mayer, Bernd, Picard, Didier
Publicado 2011

Defective glucocorticoid receptor signaling and keratinocyte-autonomous defects contribute to skin phenotype of mouse embryos lacking the Hsp90 co-chaperone p23

por Madon-Simon, Marta, Grad, Iwona, Bayo, Pilar, Pérez, Paloma, Picard, Didier
Publicado 2017

The sensitivity to Hsp90 inhibitors of both normal and oncogenically transformed cells is determined by the equilibrium between cellular quiescence and activity

por Echeverria, Pablo C., Bhattacharya, Kaushik, Joshi, Abhinav, Wang, Tai, Picard, Didier
Publicado 2019

Detection of changes in gene regulatory patterns, elicited by perturbations of the Hsp90 molecular chaperone complex, by visualizing multiple experiments with an animation

por Echeverría, Pablo C, Forafonov, Fedor, Pandey, Deo P, Mühlebach, Guillaume, Picard, Didier
Publicado 2011

Dynamic Impacts of the Inhibition of the Molecular Chaperone Hsp90 on the T-Cell Proteome Have Implications for Anti-Cancer Therapy

por Fierro-Monti, Ivo, Echeverria, Pablo, Racle, Julien, Hernandez, Celine, Picard, Didier, Quadroni, Manfredo
Publicado 2013

A genetic polymorphism repurposes the G-protein coupled and membrane-associated estrogen receptor GPER to a transcription factor-like molecule promoting paracrine signaling between...

por Pupo, Marco, Bodmer, Alexandre, Berto, Melissa, Maggiolini, Marcello, Dietrich, Pierre-Yves, Picard, Didier
Publicado 2017

Cooperative interaction between ERα and the EMT-inducer ZEB1 reprograms breast cancer cells for bone metastasis

por Mohammadi Ghahhari, Nastaran, Sznurkowska, Magdalena K., Hulo, Nicolas, Bernasconi, Lilia, Aceto, Nicola, Picard, Didier
Publicado 2022