From PK/PD to QSP: Understanding the Dynamic Effect of Cholesterol-Lowering Drugs on Atherosclerosis Progression and Stratified Medicine

por Pichardo-Almarza, Cesar, Diaz-Zuccarini, Vanessa
Publicado 2016

Understanding the Effect of Statins and Patient Adherence in Atherosclerosis via a Quantitative Systems Pharmacology Model Using a Novel, Hybrid, and Multi-Scale Approach

por Pichardo-Almarza, Cesar, Diaz-Zuccarini, Vanessa
Publicado 2017

Development of a Patient-Specific Multi-Scale Model to Understand Atherosclerosis and Calcification Locations: Comparison with In vivo Data in an Aortic Dissection

por Alimohammadi, Mona, Pichardo-Almarza, Cesar, Agu, Obiekezie, Díaz-Zuccarini, Vanessa
Publicado 2016

A multiscale modelling approach to understand atherosclerosis formation: A patient-specific case study in the aortic bifurcation

por Alimohammadi, Mona, Pichardo-Almarza, Cesar, Agu, Obiekezie, Díaz-Zuccarini, Vanessa
Publicado 2017

Towards personalised management of atherosclerosis via computational models in vascular clinics: technology based on patient-specific simulation approach

por Díaz-Zuccarini, Vanessa, Di Tomaso, Giulia, Agu, Obiekezie, Pichardo-Almarza, Cesar
Publicado 2014

Multiscale, patient-specific computational fluid dynamics models predict formation of neointimal hyperplasia in saphenous vein grafts

por Donadoni, Francesca, Pichardo-Almarza, Cesar, Homer-Vanniasinkam, Shervanthi, Dardik, Alan, Díaz-Zuccarini, Vanessa
Publicado 2020

Patient-Specific, Multi-Scale Modeling of Neointimal Hyperplasia in Vein Grafts

por Donadoni, Francesca, Pichardo-Almarza, Cesar, Bartlett, Matthew, Dardik, Alan, Homer-Vanniasinkam, Shervanthi, Díaz-Zuccarini, Vanessa
Publicado 2017

Quantitative Systems Pharmacology Model for Alzheimer Disease Indicates Targeting Sphingolipid Dysregulation as Potential Treatment Option

por Clausznitzer, Diana, Pichardo‐Almarza, Cesar, Relo, Ana Lucia, van Bergeijk, Jeroen, van der Kam, Elizabeth, Laplanche, Loic, Benson, Neil, Nijsen, Marjoleen
Publicado 2018

Minimal brain PBPK model to support the preclinical and clinical development of antibody therapeutics for CNS diseases

por Bloomingdale, Peter, Bakshi, Suruchi, Maass, Christian, van Maanen, Eline, Pichardo-Almarza, Cesar, Yadav, Daniela Bumbaca, van der Graaf, Piet, Mehrotra, Nitin
Publicado 2021

Modeling of celiac disease immune response and the therapeutic effect of potential drugs

por Demin, Oleg O, Smirnov, Sergey V, Sokolov, Victor V, Cucurull-Sanchez, Lourdes, Pichardo-Almarza, Cesar, Flores, M Victoria, Benson, Neil, Demin, Oleg V
Publicado 2013

Impaired LXRα Phosphorylation Attenuates Progression of Fatty Liver Disease

por Becares, Natalia, Gage, Matthew C., Voisin, Maud, Shrestha, Elina, Martin-Gutierrez, Lucia, Liang, Ning, Louie, Rikah, Pourcet, Benoit, Pello, Oscar M., Luong, Tu Vinh, Goñi, Saioa, Pichardo-Almarza, Cesar, Røberg-Larsen, Hanne, Diaz-Zuccarini, Vanessa, Steffensen, Knut R., O’Brien, Alastair, Garabedian, Michael J., Rombouts, Krista, Treuter, Eckardt, Pineda-Torra, Inés
Publicado 2019