Vaccination with Schistosoma mansoni Cholinesterases Reduces the Parasite Burden and Egg Viability in a Mouse Model of Schistosomiasis

por Tedla, Bemnet A., Pickering, Darren, Becker, Luke, Loukas, Alex, Pearson, Mark S.
Publicado 2020

TIMPs of parasitic helminths – a large-scale analysis of high-throughput sequence datasets

por Cantacessi, Cinzia, Hofmann, Andreas, Pickering, Darren, Navarro, Severine, Mitreva, Makedonka, Loukas, Alex
Publicado 2013

Suppression of inflammation and tissue damage by a hookworm recombinant protein in experimental colitis

por Ferreira, Ivana B, Pickering, Darren A, Troy, Sally, Croese, John, Loukas, Alex, Navarro, Severine
Publicado 2017

Complement Inhibitors from Scabies Mites Promote Streptococcal Growth – A Novel Mechanism in Infected Epidermis?

por Mika, Angela, Reynolds, Simone L., Pickering, Darren, McMillan, David, Sriprakash, Kadaba S., Kemp, David J., Fischer, Katja
Publicado 2012

Compounds Derived from the Bhutanese Daisy, Ajania nubigena, Demonstrate Dual Anthelmintic Activity against Schistosoma mansoni and Trichuris muris

por Wangchuk, Phurpa, Pearson, Mark S., Giacomin, Paul R., Becker, Luke, Sotillo, Javier, Pickering, Darren, Smout, Michael J., Loukas, Alex
Publicado 2016

Novel cholinesterase paralogs of Schistosoma mansoni have perceived roles in cholinergic signalling and drug detoxification and are essential for parasite survival

por Tedla, Bemnet A., Sotillo, Javier, Pickering, Darren, Eichenberger, Ramon M., Ryan, Stephanie, Becker, Luke, Loukas, Alex, Pearson, Mark S.
Publicado 2019

Monoclonal Antibodies Targeting an Opisthorchis viverrini Extracellular Vesicle Tetraspanin Protect Hamsters against Challenge Infection

por Phumrattanaprapin, Wuttipong, Pearson, Mark, Pickering, Darren, Tedla, Bemnet, Smout, Michael, Chaiyadet, Sujittra, Brindley, Paul J., Loukas, Alex, Laha, Thewarach
Publicado 2021

Enhanced Protective Efficacy of a Chimeric Form of the Schistosomiasis Vaccine Antigen Sm-TSP-2

por Pearson, Mark S., Pickering, Darren A., McSorley, Henry J., Bethony, Jeffrey M., Tribolet, Leon, Dougall, Annette M., Hotez, Peter J., Loukas, Alex
Publicado 2012

Insights into the Membrane Interactions of the Saposin-Like Proteins Na-SLP-1 and Ac-SLP-1 from Human and Dog Hookworm

por Willis, Charlene, Wang, Conan K., Osman, Asiah, Simon, Anne, Pickering, Darren, Mulvenna, Jason, Riboldi-Tunicliffe, Alan, Jones, Malcolm K., Loukas, Alex, Hofmann, Andreas
Publicado 2011

Schistosoma haematobium Extracellular Vesicle Proteins Confer Protection in a Heterologous Model of Schistosomiasis

por Mekonnen, Gebeyaw G., Tedla, Bemnet A., Pickering, Darren, Becker, Luke, Wang, Lei, Zhan, Bin, Bottazzi, Maria Elena, Loukas, Alex, Sotillo, Javier, Pearson, Mark S.
Publicado 2020

Polypyridylruthenium(II) complexes exert anti-schistosome activity and inhibit parasite acetylcholinesterases

por Sundaraneedi, Madhu K., Tedla, Bemnet A., Eichenberger, Ramon M., Becker, Luke, Pickering, Darren, Smout, Michael J., Rajan, Siji, Wangchuk, Phurpa, Keene, F. Richard, Loukas, Alex, Collins, J. Grant, Pearson, Mark S.
Publicado 2017

Novel Scabies Mite Serpins Inhibit the Three Pathways of the Human Complement System

por Mika, Angela, Reynolds, Simone L., Mohlin, Frida C., Willis, Charlene, Swe, Pearl M., Pickering, Darren A., Halilovic, Vanja, Wijeyewickrema, Lakshmi C., Pike, Robert N., Blom, Anna M., Kemp, David J., Fischer, Katja
Publicado 2012

Peptides derived from hookworm anti-inflammatory proteins suppress inducible colitis in mice and inflammatory cytokine production by human cells

por Cobos, Claudia, Bansal, Paramjit S., Wilson, David T., Jones, Linda, Zhao, Guangzu, Field, Matthew A., Eichenberger, Ramon M., Pickering, Darren A., Ryan, Rachael Y. M., Ratnatunga, Champa N., Miles, John J., Ruscher, Roland, Giacomin, Paul R., Navarro, Severine, Loukas, Alex, Daly, Norelle L.
Publicado 2022

An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm...

por Pearson, Mark S., Bethony, Jeffrey M., Pickering, Darren A., de Oliveira, Luciana M., Jariwala, Amar, Santiago, Helton, Miles, Aaron P., Zhan, Bin, Jiang, Desheng, Ranjit, Najju, Mulvenna, Jason, Tribolet, Leon, Plieskatt, Jordan, Smith, Tracey, Bottazzi, Maria Elena, Jones, Kathryn, Keegan, Brian, Hotez, Peter J., Loukas, Alex
Publicado 2009

Novel antiinflammatory biologics shaped by parasite–host coevolution

por Ryan, Stephanie M., Ruscher, Roland, Johnston, Wayne A., Pickering, Darren A., Kennedy, Malcolm W., Smith, Brian O., Jones, Linda, Buitrago, Geraldine, Field, Matt A., Esterman, Adrian J., McHugh, Connor P., Browne, Daniel J., Cooper, Martha M., Ryan, Rachael Y. M., Doolan, Denise L., Engwerda, Christian R., Miles, Kim, Mitreva, Makedonka, Croese, John, Rahman, Tony, Alexandrov, Kirill, Giacomin, Paul R., Loukas, Alex
Publicado 2022