Telomeric replication stress: the beginning and the end for alternative lengthening of telomeres cancers

por Lu, Robert, Pickett, Hilda A.
Publicado 2022

Alternative lengthening of telomeres: remodeling the telomere architecture

por Conomos, Dimitri, Pickett, Hilda A., Reddel, Roger R.
Publicado 2013

A DNA-fiber protocol for single molecule analysis of telomere (SMAT) length and extension events in cancer cells

por Lu, Robert, Allen, Joshua A.M., Galaviz, Pablo, Pickett, Hilda A.
Publicado 2022

Telomerase activity is associated with an increase in DNA methylation at the proximal subtelomere and a reduction in telomeric transcription

por Ng, Laura J., Cropley, Jennifer E., Pickett, Hilda A., Reddel, Roger R., Suter, Catherine M.
Publicado 2009

Control of telomere length by a trimming mechanism that involves generation of t-circles

por Pickett, Hilda A, Cesare, Anthony J, Johnston, Rebecca L, Neumann, Axel A, Reddel, Roger R
Publicado 2009

Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cells

por Conomos, Dimitri, Stutz, Michael D., Hills, Mark, Neumann, Axel A., Bryan, Tracy M., Reddel, Roger R., Pickett, Hilda A.
Publicado 2012

Progerin impairs 3D genome organization and induces fragile telomeres by limiting the dNTP pools

por Kychygina, Anna, Dall’Osto, Marina, Allen, Joshua A. M., Cadoret, Jean-Charles, Piras, Vincent, Pickett, Hilda A., Crabbe, Laure
Publicado 2021

Human telomeres that contain (CTAGGG)(n) repeats show replication dependent instability in somatic cells and the male germline

por Mendez-Bermudez, Aaron, Hills, Mark, Pickett, Hilda A., Phan, Anh Tuân, Mergny, Jean-Louis, Riou, Jean-François, Royle, Nicola J.
Publicado 2009

RTEL1 contributes to DNA replication and repair and telomere maintenance

por Uringa, Evert-Jan, Lisaingo, Kathleen, Pickett, Hilda A., Brind'Amour, Julie, Rohde, Jan-Hendrik, Zelensky, Alex, Essers, Jeroen, Lansdorp, Peter M.
Publicado 2012

Telomere extension by telomerase and ALT generates variant repeats by mechanistically distinct processes

por Lee, Michael, Hills, Mark, Conomos, Dimitri, Stutz, Michael D., Dagg, Rebecca A., Lau, Loretta M.S., Reddel, Roger R., Pickett, Hilda A.
Publicado 2014

Telomere Length Measurement by Molecular Combing

por Kahl, Vivian F. S., Allen, Joshua A. M., Nelson, Christopher B., Sobinoff, Alexander P., Lee, Michael, Kilo, Tatjana, Vasireddy, Raja S., Pickett, Hilda A.
Publicado 2020

A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase

por Killedar, Anagha, Stutz, Michael D., Sobinoff, Alexander P., Tomlinson, Christopher G., Bryan, Tracy M., Beesley, Jonathan, Chenevix-Trench, Georgia, Reddel, Roger R., Pickett, Hilda A.
Publicado 2015

Anti-recombination function of MutSα restricts telomere extension by ALT-associated homology-directed repair

por Barroso-González, Jonathan, García-Expósito, Laura, Galaviz, Pablo, Lee Lynskey, Michelle, Allen, Joshua A.M., Hoang, SongMy, Watkins, Simon C., Pickett, Hilda A., O’Sullivan, Roderick J.
Publicado 2021

Histone variant H3.3 provides the heterochromatic H3 lysine 9 tri-methylation mark at telomeres

por Udugama, Maheshi, M. Chang, Fiona T., Chan, F. Lyn, Tang, Michelle C., Pickett, Hilda A., R. McGhie, James D., Mayne, Lynne, Collas, Philippe, Mann, Jeffrey R., Wong, Lee H.
Publicado 2015

The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)

por Lu, Robert, O’Rourke, Julienne J., Sobinoff, Alexander P., Allen, Joshua A. M., Nelson, Christopher B., Tomlinson, Christopher G., Lee, Michael, Reddel, Roger R., Deans, Andrew J., Pickett, Hilda A.
Publicado 2019

Author Correction: The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)

por Lu, Robert, O’Rourke, Julienne J., Sobinoff, Alexander P., Allen, Joshua A. M., Nelson, Christopher B., Tomlinson, Christopher G., Lee, Michael, Reddel, Roger R., Deans, Andrew J., Pickett, Hilda A.
Publicado 2019

Functional dissection of breast cancer risk-associated TERT promoter variants

por Helbig, Sonja, Wockner, Leesa, Bouendeu, Annick, Hille-Betz, Ursula, McCue, Karen, French, Juliet D, Edwards, Stacey L, Pickett, Hilda A, Reddel, Roger R, Chenevix-Trench, Georgia, Dörk, Thilo, Beesley, Jonathan
Publicado 2017

Telomerase promotes formation of a telomere protective complex in cancer cells

por Perera, Omesha N., Sobinoff, Alexander P., Teber, Erdahl T., Harman, Ashley, Maritz, Michelle F., Yang, Sile F., Pickett, Hilda A., Cesare, Anthony J., Arthur, Jonathan W., MacKenzie, Karen L., Bryan, Tracy M.
Publicado 2019

Aurora Kinase B, a novel regulator of TERF1 binding and telomeric integrity

por Chan, Foong Lyn, Vinod, Benjamin, Novy, Karel, Schittenhelm, Ralf B., Huang, Cheng, Udugama, Maheshi, Nunez-Iglesias, Juan, Lin, Jane I., Hii, Linda, Chan, Julie, Pickett, Hilda A., Daly, Roger J., Wong, Lee H.
Publicado 2017

FANCM suppresses DNA replication stress at ALT telomeres by disrupting TERRA R-loops

por Pan, Xiaolei, Chen, Yun, Biju, Beena, Ahmed, Naveed, Kong, Joyce, Goldenberg, Marti, Huang, Judy, Mohan, Nandakumar, Klosek, Stephanie, Parsa, Kian, Guh, Chia-Yu, Lu, Robert, Pickett, Hilda A., Chu, Hsueh-Ping, Zhang, Dong
Publicado 2019