Human Airway Epithelial Cell Cultures for Modeling Respiratory Syncytial Virus Infection

por Pickles, Raymond J.
Publicado 2013

Respiratory syncytial virus (RSV) and its propensity for causing bronchiolitis

por Pickles, Raymond J, DeVincenzo, John P
Publicado 2015

Effects of Vitamin D on Airway Epithelial Cell Morphology and Rhinovirus Replication

por Brockman-Schneider, Rebecca A., Pickles, Raymond J., Gern, James E.
Publicado 2014

Learning from past failures: Challenges with monoclonal antibody therapies for COVID-19

por Lai, Samuel K., McSweeney, Morgan D., Pickles, Raymond J.
Publicado 2021

SARS-CoV replication and pathogenesis in an in vitro model of the human conducting airway epithelium

por Sims, Amy C., Burkett, Susan E., Yount, Boyd, Pickles, Raymond J.
Publicado 2008

Sars Cov Replication and Pathogenesis in Human Airway Airway Epithelial Cultures

por Sims, Amy C., Yount, Boyd, Burkett, Susan E., Baric, Ralph S., Pickles, Raymond J.
Publicado 2006

Growth restriction of an experimental live attenuated human parainfluenza virus type 2 vaccine in human ciliated airway epithelium in vitro parallels attenuation in African green m...

por Schaap-Nutt, Anne, Scull, Margaret A., Schmidt, Alexander C., Murphy, Brian R., Pickles, Raymond J.
Publicado 2010

Mutations in H5N1 Influenza Virus Hemagglutinin that Confer Binding to Human Tracheal Airway Epithelium

por Ayora-Talavera, Guadalupe, Shelton, Holly, Scull, Margaret A., Ren, Junyuan, Jones, Ian M., Pickles, Raymond J., Barclay, Wendy S.
Publicado 2009

Avian Influenza Virus Glycoproteins Restrict Virus Replication and Spread through Human Airway Epithelium at Temperatures of the Proximal Airways

por Scull, Margaret A., Gillim-Ross, Laura, Santos, Celia, Roberts, Kim L., Bordonali, Elena, Subbarao, Kanta, Barclay, Wendy S., Pickles, Raymond J.
Publicado 2009

AAV Exploits Subcellular Stress Associated with Inflammation, Endoplasmic Reticulum Expansion, and Misfolded Proteins in Models of Cystic Fibrosis

por Johnson, Jarrod S., Gentzsch, Martina, Zhang, Liqun, Ribeiro, Carla M. P., Kantor, Boris, Kafri, Tal, Pickles, Raymond J., Samulski, R. Jude
Publicado 2011

Tracheobronchial air-liquid interface cell culture: a model for innate mucosal defense of the upper airways?

por Kesimer, Mehmet, Kirkham, Sara, Pickles, Raymond J., Henderson, Ashley G., Alexis, Neil E., DeMaria, Genevieve, Knight, David, Thornton, David J., Sheehan, John K.
Publicado 2009

MAVS-Mediated Apoptosis and Its Inhibition by Viral Proteins

por Lei, Yu, Moore, Chris B., Liesman, Rachael M., O'Connor, Brian P., Bergstralh, Daniel T., Chen, Zhijian J., Pickles, Raymond J., Ting, Jenny P.-Y.
Publicado 2009

Human parainfluenza virus type 2 V protein inhibits interferon production and signaling and is required for replication in non-human primates

por Schaap-Nutt, Anne, D'Angelo, Christopher, Scull, Margaret A., Amaro-Carambot, Emerito, Nishio, Machiko, Pickles, Raymond J., Collins, Peter L., Murphy, Brian R., Schmidt, Alexander C.
Publicado 2010

Human T cells efficiently control RSV infection

por De, Chandrav, Pickles, Raymond J., Yao, Wenbo, Liao, Baolin, Boone, Allison, Choi, Mingyu, Battaglia, Diana M., Askin, Frederic B., Whitmire, Jason K., Silvestri, Guido, Garcia, J. Victor, Wahl, Angela
Publicado 2023

Thiol-based chemical probes exhibit antiviral activity against SARS-CoV-2 via allosteric disulfide disruption in the spike glycoprotein

por Shi, Yunlong, Zeida, Ari, Edwards, Caitlin E., Mallory, Michael L., Sastre, Santiago, Machado, Matías R., Pickles, Raymond J., Fu, Ling, Liu, Keke, Yang, Jing, Baric, Ralph S., Boucher, Richard C., Radi, Rafael, Carroll, Kate S.
Publicado 2022

CFTR Delivery to 25% of Surface Epithelial Cells Restores Normal Rates of Mucus Transport to Human Cystic Fibrosis Airway Epithelium

por Zhang, Liqun, Button, Brian, Gabriel, Sherif E., Burkett, Susan, Yan, Yu, Skiadopoulos, Mario H., Dang, Yan Li, Vogel, Leatrice N., McKay, Tristan, Mengos, April, Boucher, Richard C., Collins, Peter L., Pickles, Raymond J.
Publicado 2009

A live RSV vaccine with engineered thermostability is immunogenic in cotton rats despite high attenuation

por Stobart, Christopher C., Rostad, Christina A., Ke, Zunlong, Dillard, Rebecca S., Hampton, Cheri M., Strauss, Joshua D., Yi, Hong, Hotard, Anne L., Meng, Jia, Pickles, Raymond J., Sakamoto, Kaori, Lee, Sujin, Currier, Michael G., Moin, Syed M., Graham, Barney S., Boukhvalova, Marina S., Gilbert, Brian E., Blanco, Jorge C. G., Piedra, Pedro A., Wright, Elizabeth R., Moore, Martin L.
Publicado 2016

Precision mouse models with expanded tropism for human pathogens

por Wahl, Angela, De, Chandrav, Abad Fernandez, Maria, Lenarcic, Erik M., Xu, Yinyan, Cockrell, Adam S., Cleary, Rachel A., Johnson, Claire E., Schramm, Nathaniel J., Rank, Laura M., Newsome, Isabel G., Vincent, Heather A., Sanders, Wes, Aguilera-Sandoval, Christian R., Boone, Allison, Hildebrand, William H., Dayton, Paul A., Baric, Ralph S., Pickles, Raymond J., Braunstein, Miriam, Moorman, Nathaniel J., Goonetilleke, Nilu, Victor Garcia, J.
Publicado 2019

Pharmacokinetic-based failure of a detergent virucidal for SARS-COV-2 nasal infections

por Esther, Charles R., Kimura, Kyle S., Mikami, Yu, Edwards, Caitlin E., Das, Suman R., Freeman, Michael H., Strickland, Britton A., Brown, Hunter M., Wessinger, Bronson C., Gupta, Veerain C., Von Wahlde, Kate, Sheng, Quanhu, Huang, Li Ching, Bacon, Daniel R., Kimple, Adam J., Ceppe, Agathe S., Kato, Takafumi, Pickles, Raymond J., Randell, Scott H., Baric, Ralph S., Turner, Justin H., Boucher, Richard C.
Publicado 2021

SARS-CoV-2 Infection is Effectively Treated and Prevented by EIDD-2801

por Wahl, Angela, Gralinski, Lisa E., Johnson, Claire E., Yao, Wenbo, Kovarova, Martina, Dinnon, Kenneth H., Liu, Hongwei, Madden, Victoria J., Krzystek, Halina M., De, Chandrav, White, Kristen K., Gully, Kendra, Schäfer, Alexandra, Zaman, Tanzila, Leist, Sarah R., Grant, Paul O., Bluemling, Gregory R., Kolykhalov, Alexander A., Natchus, Michael G., Askin, Frederic B., Painter, George, Browne, Edward P., Jones, Corbin D., Pickles, Raymond J., Baric, Ralph S., Garcia, J. Victor
Publicado 2021