A Leucine Zipper Dimerization Strategy to Generate Soluble T Cell Receptors Using the Escherichia coli Expression System

por Zhang, Angela, Piechocka-Trocha, Alicja, Li, Xiaolong, Walker, Bruce D.
Publicado 2022

HLA-Cw*0102-Restricted HIV-1 p24 Epitope Variants Can Modulate the Binding of the Inhibitory KIR2DL2 Receptor and Primary NK Cell Function

por Fadda, Lena, Körner, Christian, Kumar, Swati, van Teijlingen, Nienke H., Piechocka-Trocha, Alicja, Carrington, Mary, Altfeld, Marcus
Publicado 2012

Dysregulated Tim-3 expression on natural killer cells is associated with increased Galectin-9 levels in HIV-1 infection

por Jost, Stephanie, Moreno-Nieves, Uriel Y, Garcia-Beltran, Wilfredo F, Rands, Keith, Reardon, Jeff, Toth, Ildiko, Piechocka-Trocha, Alicja, Altfeld, Marcus, Addo, Marylyn M
Publicado 2013

Increased frequencies of CD8(+)CD57(+) T cells are associated with antibody neutralization breadth against HIV in viraemic controllers

por Palmer, Christine D, Romero-Tejeda, Marisol, Scully, Eileen P, Lockhart, Ainsley, Seaman, Michael S, Goldenthal, Ariel, Piechocka-Trocha, Alicja, Walker, Bruce D, Chibnik, Lori B, Jost, Stephanie, Porichis, Filippos
Publicado 2016

Lack of Detectable HIV-1–Specific CD8(+) T Cell Responses in Zambian HIV-1–Exposed Seronegative Partners of HIV-1–Positive Individuals

por Addo, Marylyn M., Altfeld, Marcus, Brainard, Diana M., Rathod, Almas, Piechocka-Trocha, Alicja, Fideli, Ulgen, Mulenga, Joseph, Shutes, Erin, Alvino, Donna Marie L., Hunter, Eric, Allen, Susan A., Walker, Bruce D.
Publicado 2011

A high dimensional immune monitoring model of HIV-specific CD8 T cell responses accurately identifies subjects achieving spontaneous control of viral replication

por Ndhlovu, Zaza M, Chibnik, Lori B, Proudfoot, Jacqueline, Vine, Seanna, McMullen, Ashley, Cesa, Kevin, Alvino, Donna Marie, Piechocka-Trocha, Alicja, de Jager, Philip L, Kaufmann, Daniel E, Walker, Bruce D
Publicado 2012

Regulatory T Cells Expanded from HIV-1-Infected Individuals Maintain Phenotype, TCR Repertoire and Suppressive Capacity

por Angin, Mathieu, Klarenbeek, Paul L., King, Melanie, Sharma, Siddhartha M., Moodley, Eshia S., Rezai, Ashley, Piechocka-Trocha, Alicja, Toth, Ildiko, Chan, Andrew T., Goulder, Philip J., Ndung'u, Thumbi, Kwon, Douglas S., Addo, Marylyn M.
Publicado 2014

Viral adaptation to immune selection pressure by HLA class I–restricted CTL responses targeting epitopes in HIV frameshift sequences

por Berger, Christoph T., Carlson, Jonathan M., Brumme, Chanson J., Hartman, Kari L., Brumme, Zabrina L., Henry, Leah M., Rosato, Pamela C., Piechocka-Trocha, Alicja, Brockman, Mark A., Harrigan, P. Richard, Heckerman, David, Kaufmann, Daniel E., Brander, Christian
Publicado 2010

Profound Treg perturbations correlate with COVID-19 severity

por Galván-Peña, Silvia, Leon, Juliette, Chowdhary, Kaitavjeet, Michelson, Daniel A., Vijaykumar, Brinda, Yang, Liang, Magnuson, Angela M., Chen, Felicia, Manickas-Hill, Zachary, Piechocka-Trocha, Alicja, Worrall, Daniel P., Hall, Kathryn E., Ghebremichael, Musie, Walker, Bruce D., Li, Jonathan Z., Yu, Xu G., Mathis, Diane, Benoist, Christophe
Publicado 2021

Temporal changes in T cell subsets and expansion of cytotoxic CD4+ T cells in the lungs in severe COVID-19

por Kaneko, Naoki, Boucau, Julie, Kuo, Hsiao-Hsuan, Perugino, Cory, Mahajan, Vinay S., Farmer, Jocelyn R., Liu, Hang, Diefenbach, Thomas J., Piechocka-Trocha, Alicja, Lefteri, Kristina, Waring, Michael T., Premo, Katherine R., Walker, Bruce D., Li, Jonathan Z., Gaiha, Gaurav, Yu, Xu G., Lichterfeld, Mathias, Padera, Robert F., Pillai, Shiv
Publicado 2022

Structure-guided T cell vaccine design for SARS-CoV-2 variants and sarbecoviruses

por Nathan, Anusha, Rossin, Elizabeth J., Kaseke, Clarety, Park, Ryan J., Khatri, Ashok, Koundakjian, Dylan, Urbach, Jonathan M., Singh, Nishant K., Bashirova, Arman, Tano-Menka, Rhoda, Senjobe, Fernando, Waring, Michael T., Piechocka-Trocha, Alicja, Garcia-Beltran, Wilfredo F., Iafrate, A. John, Naranbhai, Vivek, Carrington, Mary, Walker, Bruce D., Gaiha, Gaurav D.
Publicado 2021

A naturally arising broad and potent CD4-binding site antibody with low somatic mutation

por Barnes, Christopher O., Schoofs, Till, Gnanapragasam, Priyanthi N.P., Golijanin, Jovana, Huey-Tubman, Kathryn E., Gruell, Henning, Schommers, Philipp, Suh-Toma, Nina, Lee, Yu Erica, Cetrulo Lorenzi, Julio C., Piechocka-Trocha, Alicja, Scheid, Johannes F., West, Anthony P., Walker, Bruce D., Seaman, Michael S., Klein, Florian, Nussenzweig, Michel C., Bjorkman, Pamela J.
Publicado 2022

Molecular basis of differential HLA class I-restricted T cell recognition of a highly networked HIV peptide

por Li, Xiaolong, Singh, Nishant Kumar, Collins, David R., Ng, Robert, Zhang, Angela, Lamothe-Molina, Pedro A., Shahinian, Peter, Xu, Shutong, Tan, Kemin, Piechocka-Trocha, Alicja, Urbach, Jonathan M., Weber, Jeffrey K., Gaiha, Gaurav D., Takou Mbah, Overbeck Christian, Huynh, Tien, Cheever, Sophia, Chen, James, Birnbaum, Michael, Zhou, Ruhong, Walker, Bruce D., Wang, Jia-huai
Publicado 2023

Integrative genomic analysis of HIV-specific CD8(+) T cells reveals that PD-1 inhibits T cell function by upregulating BATF

por Quigley, Michael, Pereyra, Florencia, Nilsson, Björn, Porichis, Filippos, Fonseca, Catia, Eichbaum, Quentin, Julg, Boris, Jesneck, Jonathan L., Brosnahan, Kathleen, Imam, Sabrina, Russell, Kate, Toth, Ildiko, Piechocka-Trocha, Alicja, Dolfi, Douglas, Angelosanto, Jill, Crawford, Alison, Shin, Haina, Kwon, Douglas S., Zupkosky, Jennifer, Francisco, Loise, Freeman, Gordon J., Wherry, E. John, Kaufmann, Daniel E., Walker, Bruce D., Ebert, Benjamin, Haining, W. Nicholas
Publicado 2010

HLA-B*14:02-Restricted Env-Specific CD8(+) T-Cell Activity Has Highly Potent Antiviral Efficacy Associated with Immune Control of HIV Infection

por Leitman, Ellen M., Willberg, Christian B., Tsai, Ming-Han, Chen, Huabiao, Buus, Søren, Chen, Fabian, Riddell, Lynn, Haas, David, Fellay, Jacques, Goedert, James J., Piechocka-Trocha, Alicja, Walker, Bruce D., Martin, Jeffrey, Deeks, Steven, Wolinsky, Steven M., Martinson, Jeremy, Martin, Maureen, Qi, Ying, Sáez-Cirión, Asier, Yang, Otto O., Matthews, Philippa C., Carrington, Mary, Goulder, Philip J. R.
Publicado 2017

HLA class-I-peptide stability mediates CD8(+) T cell immunodominance hierarchies and facilitates HLA-associated immune control of HIV

por Kaseke, Clarety, Park, Ryan J., Singh, Nishant K., Koundakjian, Dylan, Bashirova, Arman, Garcia Beltran, Wilfredo F., Takou Mbah, Overbeck C., Ma, Jiaqi, Senjobe, Fernando, Urbach, Jonathan M., Nathan, Anusha, Rossin, Elizabeth J., Tano-Menka, Rhoda, Khatri, Ashok, Piechocka-Trocha, Alicja, Waring, Michael T., Birnbaum, Michael E., Baker, Brian M., Carrington, Mary, Walker, Bruce D., Gaiha, Gaurav D.
Publicado 2021

Concanamycin A counteracts HIV-1 Nef to enhance immune clearance of infected primary cells by cytotoxic T lymphocytes

por Painter, Mark M., Zimmerman, Gretchen E., Merlino, Madeline S., Robertson, Andrew W., Terry, Valeri H., Ren, Xuefeng, McLeod, Megan R., Gomez-Rodriguez, Lyanne, Garcia, Kirsten A., Leonard, Jolie A., Leopold, Kay E., Neevel, Andrew J., Lubow, Jay, Olson, Eli, Piechocka-Trocha, Alicja, Collins, David R., Tripathi, Ashootosh, Raghavan, Malini, Walker, Bruce D., Hurley, James H., Sherman, David H., Collins, Kathleen L.
Publicado 2020

SARS-CoV-2 viral load is associated with increased disease severity and mortality

por Fajnzylber, Jesse, Regan, James, Coxen, Kendyll, Corry, Heather, Wong, Colline, Rosenthal, Alexandra, Worrall, Daniel, Giguel, Francoise, Piechocka-Trocha, Alicja, Atyeo, Caroline, Fischinger, Stephanie, Chan, Andrew, Flaherty, Keith T., Hall, Kathryn, Dougan, Michael, Ryan, Edward T., Gillespie, Elizabeth, Chishti, Rida, Li, Yijia, Jilg, Nikolaus, Hanidziar, Dusan, Baron, Rebecca M., Baden, Lindsey, Tsibris, Athe M., Armstrong, Katrina A., Kuritzkes, Daniel R., Alter, Galit, Walker, Bruce D., Yu, Xu, Li, Jonathan Z.
Publicado 2020

Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity

por Shrock, Ellen, Fujimura, Eric, Kula, Tomasz, Timms, Richard T., Lee, I-Hsiu, Leng, Yumei, Robinson, Matthew L., Sie, Brandon M., Li, Mamie Z., Chen, Yuezhou, Logue, Jennifer, Zuiani, Adam, McCulloch, Denise, Lelis, Felipe J. N., Henson, Stephanie, Monaco, Daniel R., Travers, Meghan, Habibi, Shaghayegh, Clarke, William A., Caturegli, Patrizio, Laeyendecker, Oliver, Piechocka-Trocha, Alicja, Li, Jonathan Z., Khatri, Ashok, Chu, Helen Y., Villani, Alexandra-Chloé, Kays, Kyle, Goldberg, Marcia B., Hacohen, Nir, Filbin, Michael R., Yu, Xu G., Walker, Bruce D., Wesemann, Duane R., Larman, H. Benjamin, Lederer, James A., Elledge, Stephen J.
Publicado 2020

Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19

por Kaneko, Naoki, Kuo, Hsiao-Hsuan, Boucau, Julie, Farmer, Jocelyn R., Allard-Chamard, Hugues, Mahajan, Vinay S., Piechocka-Trocha, Alicja, Lefteri, Kristina, Osborn, Matthew, Bals, Julia, Bartsch, Yannic C., Bonheur, Nathalie, Caradonna, Timothy M., Chevalier, Josh, Chowdhury, Fatema, Diefenbach, Thomas J., Einkauf, Kevin, Fallon, Jon, Feldman, Jared, Finn, Kelsey K., Garcia-Broncano, Pilar, Hartana, Ciputra Adijaya, Hauser, Blake M., Jiang, Chenyang, Kaplonek, Paulina, Karpell, Marshall, Koscher, Eric C., Lian, Xiaodong, Liu, Hang, Liu, Jinqing, Ly, Ngoc L., Michell, Ashlin R., Rassadkina, Yelizaveta, Seiger, Kyra, Sessa, Libera, Shin, Sally, Singh, Nishant, Sun, Weiwei, Sun, Xiaoming, Ticheli, Hannah J., Waring, Michael T., Zhu, Alex L., Alter, Galit, Li, Jonathan Z., Lingwood, Daniel, Schmidt, Aaron G., Lichterfeld, Mathias, Walker, Bruce D., Yu, Xu G., Padera, Robert F., Pillai, Shiv
Publicado 2020