Harnessing the Anti-Nociceptive Potential of NK2 and NK3 Ligands in the Design of New Multifunctional μ/δ-Opioid Agonist–Neurokinin Antagonist Peptidomimetics

por Gadais, Charlène, Piekielna-Ciesielska, Justyna, De Neve, Jolien, Martin, Charlotte, Janecka, Anna, Ballet, Steven
Publicado 2021

Design, Synthesis and Functional Analysis of Cyclic Opioid Peptides with Dmt-Tic Pharmacophore

por Sarkar, Arijit, Adamska-Bartlomiejczyk, Anna, Piekielna-Ciesielska, Justyna, Wtorek, Karol, Kluczyk, Alicja, Borics, Attila, Janecka, Anna
Publicado 2020

Functional selectivity of EM-2 analogs at the mu-opioid receptor

por Piekielna-Ciesielska, Justyna, Malfacini, Davide, Djeujo, Francine Medjiofack, Marconato, Chantal, Wtorek, Karol, Calo’, Girolamo, Janecka, Anna
Publicado 2023

Antinociceptive potency of a fluorinated cyclopeptide Dmt-c[D-Lys-Phe-p-CF(3)-Phe-Asp]NH(2)

por Piekielna-Ciesielska, Justyna, Mollica, Adriano, Pieretti, Stefano, Fichna, Jakub, Szymaszkiewicz, Agata, Zielińska, Marta, Kordek, Radzisław, Janecka, Anna
Publicado 2018

Pharmacological Characterization of µ-Opioid Receptor Agonists with Biased G Protein or β-Arrestin Signaling, and Computational Study of Conformational Changes during Receptor Acti...

por Piekielna-Ciesielska, Justyna, Artali, Roberto, Azzam, Ammar A. H., Lambert, David G., Kluczyk, Alicja, Gentilucci, Luca, Janecka, Anna
Publicado 2020

Synthesis, Pharmacological Evaluation, and Computational Studies of Cyclic Opioid Peptidomimetics Containing β(3)-Lysine

por Wtorek, Karol, Lipiński, Piotr F. J., Adamska-Bartłomiejczyk, Anna, Piekielna-Ciesielska, Justyna, Sukiennik, Jarosław, Kluczyk, Alicja, Janecka, Anna
Publicado 2021

Synthesis and Pharmacological Evaluation of Hybrids Targeting Opioid and Neurokinin Receptors

por Wtorek, Karol, Adamska-Bartłomiejczyk, Anna, Piekielna-Ciesielska, Justyna, Ferrari, Federica, Ruzza, Chiara, Kluczyk, Alicja, Piasecka-Zelga, Joanna, Calo’, Girolamo, Janecka, Anna
Publicado 2019

Synthesis, Biological Activity and Molecular Docking of Chimeric Peptides Targeting Opioid and NOP Receptors

por Wtorek, Karol, Ghidini, Alessia, Gentilucci, Luca, Adamska-Bartłomiejczyk, Anna, Piekielna-Ciesielska, Justyna, Ruzza, Chiara, Sturaro, Chiara, Calò, Girolamo, Pieretti, Stefano, Kluczyk, Alicja, McDonald, John, Lambert, David G., Janecka, Anna
Publicado 2022