The splicing-factor related protein SFPQ/PSF interacts with RAD51D and is necessary for homology-directed repair and sister chromatid cohesion

por Rajesh, Changanamkandath, Baker, Dustin K., Pierce, Andrew J., Pittman, Douglas L.
Publicado 2011

Recombination phenotypes of the NCI-60 collection of human cancer cells

por Stults, Dawn M, Killen, Michael W, Shelton, Brent J, Pierce, Andrew J
Publicado 2011

Escherichia coli RecG functionally suppresses human Bloom syndrome phenotypes

por Killen, Michael W, Stults, Dawn M, Wilson, William A, Pierce, Andrew J
Publicado 2012

A guide to naming human non‐coding RNA genes

por Seal, Ruth L, Chen, Ling‐Ling, Griffiths‐Jones, Sam, Lowe, Todd M, Mathews, Michael B, O'Reilly, Dawn, Pierce, Andrew J, Stadler, Peter F, Ulitsky, Igor, Wolin, Sandra L, Bruford, Elspeth A
Publicado 2020

ATM protein is deficient in over 40% of lung adenocarcinomas

por Villaruz, Liza C., Jones, Helen, Dacic, Sanja, Abberbock, Shira, Kurland, Brenda F., Stabile, Laura P., Siegfried, Jill M., Conrads, Thomas P., Smith, Neil R., O'Connor, Mark J., Pierce, Andrew J., Bakkenist, Christopher J.
Publicado 2016

SLFN11 informs on standard of care and novel treatments in a wide range of cancer models

por Winkler, Claudia, Armenia, Joshua, Jones, Gemma N., Tobalina, Luis, Sale, Matthew J., Petreus, Tudor, Baird, Tarrion, Serra, Violeta, Wang, Anderson T., Lau, Alan, Garnett, Mathew J., Jaaks, Patricia, Coker, Elizabeth A., Pierce, Andrew J., O’Connor, Mark J., Leo, Elisabetta
Publicado 2020

pRAD50: a novel and clinically applicable pharmacodynamic biomarker of both ATM and ATR inhibition identified using mass spectrometry and immunohistochemistry

por Jones, Gemma N., Rooney, Claire, Griffin, Nicola, Roudier, Martine, Young, Lucy A., Garcia-Trinidad, Antonio, Hughes, Gareth D., Whiteaker, Jeffrey R., Wilson, Zena, Odedra, Rajesh, Zhao, Lei, Ivey, Richard G., Howat, William J., Harrington, Elizabeth A., Barrett, J. Carl, Ramos-Montoya, Antonio, Lau, Alan, Paulovich, Amanda G., Cadogan, Elaine B., Pierce, Andrew J.
Publicado 2018

Phase I Study of Ceralasertib (AZD6738), a Novel DNA Damage Repair Agent, in Combination with Weekly Paclitaxel in Refractory Cancer

por Kim, Seung Tae, Smith, Simon A., Mortimer, Peter, Loembé, Arsene-Bienvenu, Cho, Heejin, Kim, Kyoung-Mee, Smith, Claire, Willis, Sophie, Irurzun-Arana, Itziar, Berges, Alienor, Hong, Jung Yong, Park, Se Hoon, Park, Joon Oh, Park, Young Suk, Lim, Ho Yeong, Kang, Won Ki, Kozarewa, Iwanka, Pierce, Andrew J., Dean, Emma, Lee, Jeeyun
Publicado 2021

Ceralasertib (AZD6738), an Oral ATR Kinase Inhibitor, in Combination with Carboplatin in Patients with Advanced Solid Tumors: A Phase I Study

por Yap, Timothy A., Krebs, Matthew G., Postel-Vinay, Sophie, El-Khouiery, Anthony, Soria, Jean-Charles, Lopez, Juanita, Berges, Alienor, Cheung, S.Y. Amy, Irurzun-Arana, Itziar, Goldwin, Andrew, Felicetti, Brunella, Jones, Gemma N., Lau, Alan, Frewer, Paul, Pierce, Andrew J., Clack, Glen, Stephens, Christine, Smith, Simon A., Dean, Emma, Hollingsworth, Simon J.
Publicado 2021

Retrospective analysis of Schlafen11 (SLFN11) to predict the outcomes to therapies affecting the DNA damage response

por Willis, Sophie E., Winkler, Claudia, Roudier, Martine P., Baird, Tarrion, Marco-Casanova, Paola, Jones, Emma V., Rowe, Philip, Rodriguez-Canales, Jaime, Angell, Helen K., Ng, Felicia S. L., Waring, Paul M., Hodgson, Darren, Ledermann, Jonathan A., Weberpals, Johanne I., Dean, Emma, Harrington, Elizabeth A., Barrett, J. Carl, Pierce, Andrew J., Leo, Elisabetta, Jones, Gemma N.
Publicado 2021

The multi-specific V(H)-based Humabody CB213 co-targets PD1 and LAG3 on T cells to promote anti-tumour activity

por Edwards, Carolyn J., Sette, Angelica, Cox, Carl, Di Fiore, Barbara, Wyre, Chris, Sydoruk, Daniela, Yadin, David, Hayes, Philip, Stelter, Szymon, Bartlett, Phillip D., Zuazo, Miren, Garcia-Granda, Maria Jesus, Benedetti, Giovanni, Fiaska, Stratoniki, Birkett, Neil R., Teng, Yumin, Enever, Carrie, Arasanz, Hugo, Bocanegra, Ana, Chocarro, Luisa, Fernandez, Gonzalo, Vera, Ruth, Archer, Bethan, Osuch, Isabelle, Lewandowska, Martyna, Surani, Yasmin M., Kochan, Grazyna, Escors, David, Legg, James, Pierce, Andrew J.
Publicado 2021

Targeted Mass Spectrometry Enables Quantification of Novel Pharmacodynamic Biomarkers of ATM Kinase Inhibition

por Whiteaker, Jeffrey R., Wang, Tao, Zhao, Lei, Schoenherr, Regine M., Kennedy, Jacob J., Voytovich, Ulianna, Ivey, Richard G., Huang, Dongqing, Lin, Chenwei, Colantonio, Simona, Caceres, Tessa W., Roberts, Rhonda R., Knotts, Joseph G., Kaczmarczyk, Jan A., Blonder, Josip, Reading, Joshua J., Richardson, Christopher W., Hewitt, Stephen M., Garcia-Buntley, Sandra S., Bocik, William, Hiltke, Tara, Rodriguez, Henry, Harrington, Elizabeth A., Barrett, J. Carl, Lombardi, Benedetta, Marco-Casanova, Paola, Pierce, Andrew J., Paulovich, Amanda G.
Publicado 2021