Why Do Countries Regulate Environmental Health Risks Differently? A Theoretical Perspective

por Clahsen, Sander C. S., van Kamp, Irene, Hakkert, Betty C., Vermeire, Theo G., Piersma, Aldert H., Lebret, Erik
Publicado 2018

New approach methodologies: A quantitative in vitro to in vivo extrapolation case study with PFASs

por Fragki, Styliani, Louisse, Jochem, Bokkers, Bas, Luijten, Mirjam, Peijnenburg, Ad, Rijkers, Deborah, Piersma, Aldert H., Zeilmaker, Marco J.
Publicado 2023

Conazole fungicides inhibit Leydig cell testosterone secretion and androgen receptor activation in vitro

por Roelofs, Maarke J.E., Temming, A. Roberto, Piersma, Aldert H., van den Berg, Martin, van Duursen, Majorie B.M.
Publicado 2014

Corrigendum to “Conazole fungicides inhibit Leydig cell testosterone secretion and androgen receptor activation in vitro” [Toxicol. Rep. 1C (2014) 271–283]

por Roelofs, Maarke J.E., Temming, A. Roberto, Piersma, Aldert H., van den Berg, Martin, van Duursen, Majorie B.M.
Publicado 2016

Going Back and Forth: Episomal Vector Reprogramming of Peripheral Blood Mononuclear Cells to Induced Pluripotent Stem Cells and Subsequent Differentiation into Cardiomyocytes and N...

por de Leeuw, Victoria C., van Oostrom, Conny T.M., Imholz, Sandra, Piersma, Aldert H., Hessel, Ellen V.S., Dollé, Martijn E.T.
Publicado 2020

Glucocorticoid receptor-dependent induction of cripto-1 (one-eyed pinhead) inhibits zebrafish caudal fin regeneration

por Garland, Michael A., Sengupta, Sumitra, Mathew, Lijoy K., Truong, Lisa, de Jong, Esther, Piersma, Aldert H., La Du, Jane, Tanguay, Robert L.
Publicado 2019

Pluripotent stem cell assays: Modalities and applications for predictive developmental toxicity

por Piersma, Aldert H., Baker, Nancy C., Daston, George P., Flick, Burkhard, Fujiwara, Michio, Knudsen, Thomas B., Spielmann, Horst, Suzuki, Noriyuki, Tsaioun, Katya, Kojima, Hajime
Publicado 2022

Neuronal differentiation pathways and compound-induced developmental neurotoxicity in the human neural progenitor cell test (hNPT) revealed by RNA-seq

por de Leeuw, Victoria C., van Oostrom, Conny T.M., Wackers, Paul F.K., Pennings, Jeroen L.A., Hodemaekers, Hennie M., Piersma, Aldert H., Hessel, Ellen V.S.
Publicado 2022

Natural language processing in toxicology: Delineating adverse outcome pathways and guiding the application of new approach methodologies

por Corradi, Marie P.F., de Haan, Alyanne M., Staumont, Bernard, Piersma, Aldert H., Geris, Liesbet, Pieters, Raymond H.H., Krul, Cyrille A.M., Teunis, Marc A.T.
Publicado 2022

Next-generation text-mining mediated generation of chemical response-specific gene sets for interpretation of gene expression data

por Hettne, Kristina M, Boorsma, André, van Dartel, Dorien A M, Goeman, Jelle J, de Jong, Esther, Piersma, Aldert H, Stierum, Rob H, Kleinjans, Jos C, Kors, Jan A
Publicado 2013

Prenatal Phthalate, Perfluoroalkyl Acid, and Organochlorine Exposures and Term Birth Weight in Three Birth Cohorts: Multi-Pollutant Models Based on Elastic Net Regression

por Lenters, Virissa, Portengen, Lützen, Rignell-Hydbom, Anna, Jönsson, Bo A.G., Lindh, Christian H., Piersma, Aldert H., Toft, Gunnar, Bonde, Jens Peter, Heederik, Dick, Rylander, Lars, Vermeulen, Roel
Publicado 2015

Lasting Effects on Body Weight and Mammary Gland Gene Expression in Female Mice upon Early Life Exposure to n-3 but Not n-6 High-Fat Diets

por Luijten, Mirjam, Singh, Amar V., Bastian, Caleb A., Westerman, Anja, Pisano, M. Michele, Pennings, Jeroen L. A., Verhoef, Aart, Green, Maia L., Piersma, Aldert H., de Vries, Annemieke, Knudsen, Thomas B.
Publicado 2013

Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use

por Aschner, Michael, Ceccatelli, Sandra, Daneshian, Mardas, Fritsche, Ellen, Hasiwa, Nina, Hartung, Thomas, Hogberg, Helena T., Leist, Marcel, Li, Abby, Mundy, William R., Padilla, Stephanie, Piersma, Aldert H., Bal-Price, Anna, Seiler, Andrea, Westerink, Remco H., Zimmer, Bastian, Lein, Pamela J.
Publicado 2016

Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes

por Fritsche, Ellen, Grandjean, Philippe, Crofton, Kevin M., Aschner, Michael, Goldberg, Alan, Heinonen, Tuula, Hessel, Ellen V.S., Hogberg, Helena T., Bennekou, Susanne Hougaard, Lein, Pamela J., Leist, Marcel, Mundy, William R., Paparella, Martin, Piersma, Aldert H., Sachana, Magdalini, Schmuck, Gabriele, Solecki, Roland, Terron, Andrea, Monnet-Tschudi, Florianne, Wilks, Martin F., Witters, Hilda, Zurich, Marie-Gabrielle, Bal-Price, Anna
Publicado 2018

Comparison of rat and rabbit embryo–fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects

por Theunissen, Peter T., Beken, Sonja, Beyer, Bruce K., Breslin, William J., Cappon, Gregg D., Chen, Connie L., Chmielewski, Gary, De Schaepdrijver, Luc, Enright, Brian, Foreman, Jennifer E., Harrouk, Wafa, Hew, Kok-Wah, Hoberman, Alan M., Hui, Julia Y., Knudsen, Thomas B., Laffan, Susan B., Makris, Susan L., Martin, Matt, McNerney, Mary Ellen, Siezen, Christine L., Stanislaus, Dinesh J., Stewart, Jane, Thompson, Kary E., Tornesi, Belen, Van der Laan, Jan Willem, Weinbauer, Gerhard F., Wood, Sandra, Piersma, Aldert H.
Publicado 2016