Quantitative analysis of taxane drug target engagement of microtubules in circulating tumor cells from metastatic castration resistant prostate cancer patients treated with CRXL301...

por Mukhtar, Eiman, Worroll, Daniel, Galletti, Giuseppe, Schuster, Shelly, Piha-Paul, Sarina A., Giannakakou, Paraskevi
Publicado 2020

A mutation-specific, single-arm, phase 2 study of dovitinib in patients with advanced malignancies

por Taylor, Matthew H., Alva, Ajjai S., Larson, Timothy, Szpakowski, Sebastian, Purkaystha, Das, Amin, Alpesh, Karpiak, Linda, Piha-Paul, Sarina A.
Publicado 2020

Pembrolizumab in vaginal and vulvar squamous cell carcinoma: a case series from a phase II basket trial

por How, Jeffrey A., Jazaeri, Amir A., Soliman, Pamela T., Fleming, Nicole D., Gong, Jing, Piha-Paul, Sarina A., Janku, Filip, Stephen, Bettzy, Naing, Aung
Publicado 2021

Advanced gynecologic malignancies treated with a combination of the VEGF inhibitor bevacizumab and the mTOR inhibitor temsirolimus

por Piha-Paul, Sarina A., Wheler, Jennifer J., Fu, Siqing, Levenback, Charles, Lu, Karen, Falchook, Gerald S., Naing, Aung, Hong, David S., Tsimberidou, Apostolia M., Kurzrock, Razelle
Publicado 2014

The Effect of Renal Impairment on the Pharmacokinetics and Safety of Talazoparib in Patients with Advanced Solid Tumors

por Durairaj, Chandrasekar, Chakrabarti, Jayeta, Ferrario, Cristiano, Hirte, Holger W., Babu, Sunil, Piha-Paul, Sarina A., Plotka, Anna, Hoffman, Justin, Shi, Haihong, Wang, Diane D.
Publicado 2021

Evaluation of pharmacokinetics and safety of talazoparib in patients with advanced cancer and varying degrees of hepatic impairment

por Guo, Cen, Yu, Yanke, Chakrabarti, Jayeta, Piha‐Paul, Sarina A., Moroose, Rebecca, Plotka, Anna, Shi, Haihong, Durairaj, Chandrasekar, Wang, Diane D., Wainberg, Zev A.
Publicado 2022

Preclinical investigations and a first-in-human phase I trial of M4112, the first dual inhibitor of indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase 2, in patients with...

por Naing, Aung, Eder, Joseph P, Piha-Paul, Sarina A, Gimmi, Claude, Hussey, Elizabeth, Zhang, Sen, Hildebrand, Vera, Hosagrahara, Vinayak, Habermehl, Christina, Moisan, Jacques, Papadopoulos, Kyriakos P
Publicado 2020

Efficacy and safety of buparlisib, a PI3K inhibitor, in patients with malignancies harboring a PI3K pathway activation: a phase 2, open-label, single-arm study

por Piha-Paul, Sarina A., Taylor, Matthew H., Spitz, Daniel, Schwartzberg, Lee, Beck, J. Thaddeus, Bauer, Todd M., Meric-Bernstam, Funda, Purkayastha, Das, Karpiak, Linda, Szpakowski, Sebastian, Braiteh, Fadi
Publicado 2019

Dual EGFR inhibition in combination with anti-VEGF treatment in colorectal cancer

por Falchook, Gerald S., Naing, Aung, Wheler, Jennifer J., Tsimberidou, Apostolia M., Zinner, Ralph, Hong, David S., Fu, Siqing, Piha-Paul, Sarina A., Janku, Filip, Hess, Kenneth R., Bastida, Christel, Kurzrock, Razelle
Publicado 2014

A first-in-human phase I study of TAS0728, an oral covalent binding inhibitor of HER2, in patients with advanced solid tumors with HER2 or HER3 aberrations

por Piha-Paul, Sarina A., Azaro, Analía, Arkenau, Hendrik Tobias, Oh, Do-Youn, Galsky, Matthew D., Pal, Sumanta Kumar, Hamada, Kensuke, He, Yaohua, Yamamiya, Ikuo, Benhadji, Karim A, Hollebecque, Antoine
Publicado 2021

Dual EGFR inhibition in combination with anti-VEGF treatment: A phase I clinical trial in non-small cell lung cancer

por Falchook, Gerald S., Naing, Aung, Hong, David S., Zinner, Ralph, Fu, Siqing, Piha-Paul, Sarina A., Tsimberidou, Apostolia M., Morgan-Linnell, Sonia K., Jiang, Yunfang, Bastida, Christel, Wheler, Jennifer J., Kurzrock, Razelle
Publicado 2013

Signature program: a platform of basket trials

por Slosberg, Eric D., Kang, Barinder P., Peguero, Julio, Taylor, Matthew, Bauer, Todd M., Berry, Donald A., Braiteh, Fadi, Spira, Alexander, Meric-Bernstam, Funda, Stein, Steven, Piha-Paul, Sarina A., Salvado, August
Publicado 2018

Multidisciplinary Care of a Large Brain Metastasis in a Patient with Hormone-Receptor-Positive Breast Cancer with Ataxia-Telangiectasia Mutation

por Chelariu-Raicu, Anca, Piha-Paul, Sarina A., Chavez-MacGregor, Mariana, Johnson, Jason, Sawaya, Raymond, McAleer, Mary Frances, Nguyen, Alissa, Hartnett, Audrey, Tsimberidou, Apostolia M., Meric-Bernstam, Funda, Dumbrava, Ecaterina E.
Publicado 2023

Dual EGFR blockade with cetuximab and erlotinib combined with anti-VEGF antibody bevacizumab in advanced solid tumors: a phase 1 dose escalation triplet combination trial

por Subbiah, Vivek, Dumbrava, Ecaterina Ileana, Jiang, Yunfang, Thein, Kyaw Z., Naing, Aung, Hong, David S., Fu, Siqing, Piha-Paul, Sarina A., Tsimberidou, Apostolia M., Janku, Filip, Meric-Bernstam, Funda, Kurzrock, Razelle, Falchook, Gerald
Publicado 2020

Pharmacokinetics and safety of niraparib in patients with moderate hepatic impairment

por Akce, Mehmet, El-Khoueiry, Anthony, Piha-Paul, Sarina A., Bacque, Emeline, Pan, Peng, Zhang, Zhi-Yi, Ewesuedo, Reginald, Gupta, Divya, Tang, Yongqiang, Milton, Ashley, Zajic, Stefan, Judson, Patricia L., O’Bryant, Cindy L.
Publicado 2021

FBXW7 Mutations in Patients with Advanced Cancers: Clinical and Molecular Characteristics and Outcomes with mTOR Inhibitors

por Jardim, Denis L., Wheler, Jennifer J., Hess, Kenneth, Tsimberidou, Apostolia M., Zinner, Ralph, Janku, Filip, Subbiah, Vivek, Naing, Aung, Piha-Paul, Sarina A., Westin, Shannon N., Roy-Chowdhuri, Sinchita, Meric-Bernstam, Funda, Hong, David S.
Publicado 2014

Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway

por Wheler, Jennifer J., Moulder, Stacy L., Naing, Aung, Janku, Filip, Piha-Paul, Sarina A., Falchook, Gerald S., Zinner, Ralph, Tsimberidou, Apostolia M., Fu, Siqing, Hong, David S., Atkins, Johnique T., Yelensky, Roman, Stephens, Philip J., Kurzrock, Razelle
Publicado 2014

Advanced malignancies treated with a combination of the VEGF inhibitor bevacizumab, anti-EGFR antibody cetuximab, and the mTOR inhibitor temsirolimus

por Liu, Xiaochun, Kambrick, Susan, Fu, Siqing, Naing, Aung, Subbiah, Vivek, Blumenschein, George R., Glisson, Bonnie S., Kies, Merrill S., Tsimberidou, Apostolia M., Wheler, Jennifer J., Zinner, Ralph G., Hong, David S., Kurzrock, Razelle, Piha-Paul, Sarina A.
Publicado 2016

Associations between the gut microbiome and fatigue in cancer patients

por Hajjar, Joud, Mendoza, Tito, Zhang, Liangliang, Fu, Siqing, Piha-Paul, Sarina A., Hong, David S., Janku, Filip, Karp, Daniel D., Ballhausen, Alexej, Gong, Jing, Zarifa, Abdulrazzak, Peterson, Christine B., Meric-Bernstam, Funda, Jenq, Robert, Naing, Aung
Publicado 2021

PIK3CA Mutations in Advanced Cancers: Characteristics and Outcomes

por Janku, Filip, Wheler, Jennifer J., Naing, Aung, Stepanek, Vanda M., Falchook, Gerald S., Fu, Siqing, Garrido-Laguna, Ignacio, Tsimberidou, Apostolia M., Piha-Paul, Sarina A., Moulder, Stacy L., Lee, J. Jack, Luthra, Rajyalakshmi, Hong, David S., Kurzrock, Razelle
Publicado 2012