Pre-Clinical Drug Testing in 2D and 3D Human In Vitro Models of Glioblastoma Incorporating Non-Neoplastic Astrocytes: Tunneling Nano Tubules and Mitochondrial Transfer Modulates Ce...

por Civita, Prospero, M. Leite, Diana, Pilkington, Geoffrey J.
Publicado 2019

Receptors for Hyaluronic Acid and Poliovirus: A Combinatorial Role in Glioma Invasion?

por Maherally, Zaynah, Smith, James R., An, Qian, Pilkington, Geoffrey J.
Publicado 2012

Small molecule inhibition of Axl receptor tyrosine kinase potently suppresses multiple malignant properties of glioma cells

por Vouri, Mikaella, An, Qian, Birt, Matthew, Pilkington, Geoffrey J., Hafizi, Sassan
Publicado 2015

A Systematic Approach to Review of in vitro Methods in Brain Tumour Research (SAToRI-BTR): Development of a Preliminary Checklist for Evaluating Quality and Human Relevance

por Bracher, Mike, Pilkington, Geoffrey J., Hanemann, C. Oliver, Pilkington, Karen
Publicado 2020

The Role of Hypoxia in Glioblastoma Invasion

por Monteiro, Ana Rita, Hill, Richard, Pilkington, Geoffrey J., Madureira, Patrícia A.
Publicado 2017

Caveolin-1, a Key Mediator Across Multiple Pathways in Glioblastoma and an Independent Negative Biomarker of Patient Survival

por Moriconi, Chiara, Civita, Prospero, Neto, Catia, Pilkington, Geoffrey J., Gumbleton, Mark
Publicado 2021

Satellitosis, a Crosstalk between Neurons, Vascular Structures and Neoplastic Cells in Brain Tumours; Early Manifestation of Invasive Behaviour

por Civita, Prospero, Valerio, Ortenzi, Naccarato, Antonio Giuseppe, Gumbleton, Mark, Pilkington, Geoffrey J.
Publicado 2020

The Regulation and Function of Lactate Dehydrogenase A: Therapeutic Potential in Brain Tumor

por Valvona, Cara J., Fillmore, Helen L., Nunn, Peter B., Pilkington, Geoffrey J.
Publicado 2015

Fucosyltransferase 4 and 7 mediates adhesion of non-small cell lung cancer cells to brain-derived endothelial cells and results in modification of the blood–brain-barrier: in vitro...

por Jassam, Samah A., Maherally, Zaynah, Ashkan, Keyoumars, Pilkington, Geoffrey J., Fillmore, Helen L.
Publicado 2019

TNF-α enhancement of CD62E mediates adhesion of non–small cell lung cancer cells to brain endothelium via CD15 in lung-brain metastasis

por Jassam, Samah A., Maherally, Zaynah, Smith, James R., Ashkan, Keyoumars, Roncaroli, Federico, Fillmore, Helen L., Pilkington, Geoffrey J.
Publicado 2016

CD15s/CD62E Interaction Mediates the Adhesion of Non-Small Cell Lung Cancer Cells on Brain Endothelial Cells: Implications for Cerebral Metastasis

por Jassam, Samah A., Maherally, Zaynah, Smith, James R., Ashkan, Keyoumars, Roncaroli, Federico, Fillmore, Helen L., Pilkington, Geoffrey J.
Publicado 2017

Real-time acquisition of transendothelial electrical resistance in an all-human, in vitro, 3-dimensional, blood–brain barrier model exemplifies tight-junction integrity

por Maherally, Zaynah, Fillmore, Helen L., Tan, Sim Ling, Tan, Suk Fei, Jassam, Samah A., Quack, Friederike I., Hatherell, Kathryn E., Pilkington, Geoffrey J.
Publicado 2018

Zonulin and blood–brain barrier permeability are dissociated in humans

por Stuart, Charlotte M., Varatharaj, Aravinthan, Winberg, Martin E., Galea, Pascale, Larsson, Henrik B. W., Cramer, Stig P., Fasano, Alessio, Maherally, Zaynah, Pilkington, Geoffrey J., Keita, Åsa V., Galea, Ian
Publicado 2022

Multiregional Sequencing of IDH-WT Glioblastoma Reveals High Genetic Heterogeneity and a Dynamic Evolutionary History

por Franceschi, Sara, Civita, Prospero, Pasqualetti, Francesco, Lessi, Francesca, Modena, Martina, Barachini, Serena, Morelli, Mariangela, Santonocito, Orazio, Vannozzi, Riccardo, Pilkington, Geoffrey J., Ortenzi, Valerio, Naccarato, Antonio Giuseppe, Aretini, Paolo, Mazzanti, Chiara Maria
Publicado 2021

DIVERSet JAG Compounds Inhibit Topoisomerase II and Are Effective Against Adult and Pediatric High-Grade Gliomas

por Howarth, Alison, Simms, Claire, Kerai, Nitesh, Allen, Olivia, Mihajluk, Karina, Madureira, Patricia A., Sokratous, Giannis, Cragg, Simon, Lee, Sang Y., Morley, Andy D., Ashkan, Keyoumars, Cox, Paul A., Pilkington, Geoffrey J., Hill, Richard
Publicado 2019

Identification and functional prediction of mitochondrial complex III and IV mutations associated with glioblastoma

por Lloyd, Rhiannon E., Keatley, Kathleen, Littlewood, D. Timothy J., Meunier, Brigitte, Holt, William V., An, Qian, Higgins, Samantha C., Polyzoidis, Stavros, Stephenson, Katie F., Ashkan, Keyoumars, Fillmore, Helen L., Pilkington, Geoffrey J., McGeehan, John E.
Publicado 2015

THER-11. PEPTIDE-MEDIATED PERMEABILIZATION OF THE BLOOD-BRAIN BARRIER IMPROVES DRUG DELIVERY TO BRAIN METASTASIS

por Aasen, Synnøve Nymark, Espedal, Heidi, Holte, Christopher, Keunen, Olivier, Karlsen, Tine Veronika, Tenstad, Olav, Maherally, Zaynah, Miletic, Hrvoje, Hoang, Tuyen, Eikeland, Anne Vaag, Baghirov, Habib, Olberg, Dag Erlend, Pilkington, Geoffrey J, Sarkar, Gobinda, Jenkins, Robert, Sundstrøm, Terje, Bjerkvig, Rolf, Thorsen, Frits
Publicado 2019

Integrated Approach Reveals Role of Mitochondrial Germ-Line Mutation F18L in Respiratory Chain, Oxidative Alterations, Drug Sensitivity, and Patient Prognosis in Glioblastoma

por Keatley, Kathleen, Stromei-Cleroux, Samuel, Wiltshire, Tammy, Rajala, Nina, Burton, Gary, Holt, William V., Littlewood, D. Timothy J., Briscoe, Andrew G., Jung, Josephine, Ashkan, Keyoumars, Heales, Simon J., Pilkington, Geoffrey J., Meunier, Brigitte, McGeehan, John E., Hargreaves, Iain P., McGeehan, Rhiannon E.
Publicado 2019

Highlights of Children with Cancer UK’s Workshop on Drug Delivery in Paediatric Brain Tumours

por Nailor, Audrey, Walker, David A, Jacques, Thomas S, Warren, Kathy E, Brem, Henry, Kearns, Pamela R, Greenwood, John, Penny, Jeffrey I, Pilkington, Geoffrey J, Carcaboso, Angel M, Fleischhack, Gudrun, Macarthur, Donald, Slavc, Irene, Meijer, Lisethe, Gill, Steven, Lowis, Stephen, van Vuurden, Dannis G, Pearl, Monica S, Clifford, Steven C, Morrissy, Sorana, Ivanov, Delyan P, Beccaria, Kévin, Gilbertson, Richard J, Straathof, Karin, Green, Jordan J, Smith, Stuart, Rahman, Ruman, Kilday, John-Paul
Publicado 2016