A plant-derived VLP influenza vaccine elicits a balanced immune response even in very old mice with co-morbidities

por Hodgins, Breanna, Pillet, Stephane, Landry, Nathalie, Ward, Brian James
Publicado 2019

Prime-pull vaccination with a plant-derived virus-like particle influenza vaccine elicits a broad immune response and protects aged mice from death and frailty after challenge

por Hodgins, Breanna, Pillet, Stephane, Landry, Nathalie, Ward, Brian J.
Publicado 2019

The establishment of surrogates and correlates of protection: Useful tools for the licensure of effective influenza vaccines?

por Ward, Brian J., Pillet, Stephane, Charland, Nathalie, Trepanier, Sonia, Couillard, Julie, Landry, Nathalie
Publicado 2018

Sustained protection against Ebola virus infection following treatment of infected nonhuman primates with ZMAb

por Qiu, Xiangguo, Audet, Jonathan, Wong, Gary, Fernando, Lisa, Bello, Alexander, Pillet, Stéphane, Alimonti, Judie B., Kobinger, Gary P.
Publicado 2013

Immunogenicity and safety of a quadrivalent plant-derived virus like particle influenza vaccine candidate—Two randomized Phase II clinical trials in 18 to 49 and ≥50 years old adul...

por Pillet, Stéphane, Couillard, Julie, Trépanier, Sonia, Poulin, Jean-François, Yassine-Diab, Bader, Guy, Bruno, Ward, Brian J., Landry, Nathalie
Publicado 2019

Humoral and cell-mediated immune responses to H5N1 plant-made virus-like particle vaccine are differentially impacted by alum and GLA-SE adjuvants in a Phase 2 clinical trial

por Pillet, Stéphane, Aubin, Éric, Trépanier, Sonia, Poulin, Jean-François, Yassine-Diab, Bader, ter Meulen, Jan, Ward, Brian J., Landry, Nathalie
Publicado 2018

Elimination of receptor binding by influenza hemagglutinin improves vaccine-induced immunity

por Hendin, Hilary E., Lavoie, Pierre-Olivier, Gravett, Jason M., Pillet, Stéphane, Saxena, Pooja, Landry, Nathalie, D’Aoust, Marc-André, Ward, Brian J.
Publicado 2022

Robust induction of functional humoral response by a plant-derived Coronavirus-like particle vaccine candidate for COVID-19

por Kaplonek, Paulina, Cizmeci, Deniz, Lee, Jessica Shih-Lu, Shin, Sally A., Fischinger, Stephanie, Gobeil, Philipe, Pillet, Stéphane, Charland, Nathalie, Ward, Brian J., Alter, Galit
Publicado 2023

Cellular Immunity Is Critical for Assessing COVID-19 Vaccine Effectiveness in Immunocompromised Individuals

por Paramithiotis, Eustache, Sugden, Scott, Papp, Eszter, Bonhomme, Marie, Chermak, Todd, Crawford, Stephanie Y., Demetriades, Stefanie Z., Galdos, Gerson, Lambert, Bruce L., Mattison, John, McDade, Thomas, Pillet, Stephane, Murphy, Robert
Publicado 2022

Plant-derived virus-like particle vaccines drive cross-presentation of influenza A hemagglutinin peptides by human monocyte-derived macrophages

por Makarkov, Alexander I., Golizeh, Makan, Ruiz-Lancheros, Elizabeth, Gopal, Angelica A., Costas-Cancelas, Ian N., Chierzi, Sabrina, Pillet, Stephane, Charland, Nathalie, Landry, Nathalie, Rouiller, Isabelle, Wiseman, Paul W., Ndao, Momar, Ward, Brian J.
Publicado 2019

Durability and cross-reactivity of immune responses induced by a plant-based virus-like particle vaccine for COVID-19

por Gobeil, Philipe, Pillet, Stéphane, Boulay, Iohann, Charland, Nathalie, Lorin, Aurélien, Cheng, Matthew P., Vinh, Donald C., Boutet, Philippe, Van Der Most, Robbert, Roman, François, Ceregido, Maria Angeles, Landry, Nathalie, D’Aoust, Marc-André, Ward, Brian J.
Publicado 2022

Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19

por Ward, Brian J., Gobeil, Philipe, Séguin, Annie, Atkins, Judith, Boulay, Iohann, Charbonneau, Pierre-Yves, Couture, Manon, D’Aoust, Marc-André, Dhaliwall, Jiwanjeet, Finkle, Carolyn, Hager, Karen, Mahmood, Asif, Makarkov, Alexander, Cheng, Matthew P., Pillet, Stéphane, Schimke, Patricia, St-Martin, Sylvie, Trépanier, Sonia, Landry, Nathalie
Publicado 2021

Safety, immunogenicity, and protection provided by unadjuvanted and adjuvanted formulations of a recombinant plant-derived virus-like particle vaccine candidate for COVID-19 in non...

por Pillet, Stéphane, Arunachalam, Prabhu S., Andreani, Guadalupe, Golden, Nadia, Fontenot, Jane, Aye, Pyone Pyone, Röltgen, Katharina, Lehmicke, Gabrielle, Gobeil, Philipe, Dubé, Charlotte, Trépanier, Sonia, Charland, Nathalie, D’Aoust, Marc-André, Russell-Lodrigue, Kasi, Monjure, Christopher, Blair, Robert V., Boyd, Scott D., Bohm, Rudolf P., Rappaport, Jay, Villinger, François, Landry, Nathalie, Pulendran, Bali, Ward, Brian J.
Publicado 2022

Safety and immunogenicity of an AS03-adjuvanted plant-based SARS-CoV-2 vaccine in Adults with and without Comorbidities

por Charland, Nathalie, Gobeil, Philipe, Pillet, Stéphane, Boulay, Iohann, Séguin, Annie, Makarkov, Alexander, Heizer, Gretchen, Bhutada, Kapil, Mahmood, Asif, Trépanier, Sonia, Hager, Karen, Jiang-Wright, Julia, Atkins, Judith, Saxena, Pooja, Cheng, Matthew P., Vinh, Donald C., Boutet, Philippe, Roman, François, Van Der Most, Robbert, Ceregido, Maria Angeles, Dionne, Marc, Tellier, Guy, Gauthier, Jean-Sébastien, Essink, Brandon, Libman, Michael, Haffizulla, Jason, Fréchette, André, D’Aoust, Marc-André, Landry, Nathalie, Ward, Brian J.
Publicado 2022

Efficacy and Safety of a Recombinant Plant-Based Adjuvanted Covid-19 Vaccine

por Hager, Karen J., Pérez Marc, Gonzalo, Gobeil, Philipe, Diaz, Ricardo S., Heizer, Gretchen, Llapur, Conrado, Makarkov, Alexander I., Vasconcellos, Eduardo, Pillet, Stéphane, Riera, Fernando, Saxena, Pooja, Geller Wolff, Priscila, Bhutada, Kapil, Wallace, Garry, Aazami, Hessam, Jones, Christine E., Polack, Fernando P., Ferrara, Luciana, Atkins, Judith, Boulay, Iohann, Dhaliwall, Jiwanjeet, Charland, Nathalie, Couture, Manon M.J., Jiang-Wright, Julia, Landry, Nathalie, Lapointe, Sophie, Lorin, Aurélien, Mahmood, Asif, Moulton, Lawrence H., Pahmer, Emmy, Parent, Julie, Séguin, Annie, Tran, Luan, Breuer, Thomas, Ceregido, Maria-Angeles, Koutsoukos, Marguerite, Roman, François, Namba, Junya, D’Aoust, Marc-André, Trepanier, Sonia, Kimura, Yosuke, Ward, Brian J.
Publicado 2022