Pathogenetic, Prognostic, and Therapeutic Role of Fatty Acid Synthase in Human Hepatocellular Carcinoma

por Che, Li, Paliogiannis, Panagiotis, Cigliano, Antonio, Pilo, Maria G., Chen, Xin, Calvisi, Diego F.
Publicado 2019

Corrigendum: Pathogenetic, Prognostic, and Therapeutic Role of Fatty Acid Synthase in Human Hepatocellular Carcinoma

por Che, Li, Paliogiannis, Panagiotis, Cigliano, Antonio, Pilo, Maria G., Chen, Xin, Calvisi, Diego F.
Publicado 2022

SCD1 Expression Is Dispensable for Hepatocarcinogenesis Induced by AKT and Ras Oncogenes in Mice

por Li, Lei, Wang, Chunmei, Calvisi, Diego F., Evert, Matthias, Pilo, Maria G., Jiang, Lijie, Yuneva, Mariia, Chen, Xin
Publicado 2013

Tankyrase inhibitors suppress hepatocellular carcinoma cell growth via modulating the Hippo cascade

por Jia, Jiaoyuan, Qiao, Yu, Pilo, Maria G., Cigliano, Antonio, Liu, Xianqiong, Shao, Zixuan, Calvisi, Diego F., Chen, Xin
Publicado 2017

PI3K/AKT/mTOR pathway plays a major pathogenetic role in glycogen accumulation and tumor development in renal distal tubules of rats and men

por Ribback, Silvia, Cigliano, Antonio, Kroeger, Nils, Pilo, Maria G., Terracciano, Luigi, Burchardt, Martin, Bannasch, Peter, Calvisi, Diego F., Dombrowski, Frank
Publicado 2015

Loss of Pten synergizes with c-Met to promote hepatocellular carcinoma development via mTORC2 pathway

por Xu, Zhong, Hu, Junjie, Cao, Hui, Pilo, Maria G, Cigliano, Antonio, Shao, Zixuan, Xu, Meng, Ribback, Silvia, Dombrowski, Frank, Calvisi, Diego F, Chen, Xin
Publicado 2018

Functional role of SGK3 in PI3K/Pten driven liver tumor development

por Cao, Hui, Xu, Zhong, Wang, Jingxiao, Cigliano, Antonio, Pilo, Maria G., Ribback, Silvia, Zhang, Shu, Qiao, Yu, Che, Li, Pascale, Rosa M., Calvisi, Diego F., Chen, Xin
Publicado 2019

The Epidermal Growth Factor Receptor (EGFR) Inhibitor Gefitinib Reduces but Does Not Prevent Tumorigenesis in Chemical and Hormonal Induced Hepatocarcinogenesis Rat Models

por Ribback, Silvia, Sailer, Verena, Böhning, Enrico, Günther, Julia, Merz, Jaqueline, Steinmüller, Frauke, Utpatel, Kirsten, Cigliano, Antonio, Peters, Kristin, Pilo, Maria G., Evert, Matthias, Calvisi, Diego F., Dombrowski, Frank
Publicado 2016

Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice

por Hu, Junjie, Che, Li, Li, Lei, Pilo, Maria G., Cigliano, Antonio, Ribback, Silvia, Li, Xiaolei, Latte, Gavinella, Mela, Marta, Evert, Matthias, Dombrowski, Frank, Zheng, Guohua, Chen, Xin, Calvisi, Diego F.
Publicado 2016

Inhibition of HSF1 suppresses the growth of hepatocarcinoma cell lines in vitro and AKT-driven hepatocarcinogenesis in mice

por Cigliano, Antonio, Wang, Chunmei, Pilo, Maria G., Szydlowska, Marta, Brozzetti, Stefania, Latte, Gavinella, Pes, Giovanni M., Pascale, Rosa M., Seddaiu, Maria A., Vidili, Gianpaolo, Ribback, Silvia, Dombrowski, Frank, Evert, Matthias, Chen, Xin, Calvisi, Diego F.
Publicado 2017

Deregulated c-Myc requires a functional HSF1 for experimental and human hepatocarcinogenesis

por Cigliano, Antonio, Pilo, Maria G., Li, Lei, Latte, Gavinella, Szydlowska, Marta, Simile, Maria M., Paliogiannis, Panagiotis, Che, Li, Pes, Giovanni M., Palmieri, Giuseppe, Sini, Maria C., Cossu, Antonio, Porcu, Alberto, Vidili, Gianpaolo, Seddaiu, Maria A., Pascale, Rosa M., Ribback, Silvia, Dombrowski, Frank, Chen, Xin, Calvisi, Diego F.
Publicado 2017

Correction: The Hippo pathway efector TAZ induces intrahepatic cholangiocarcinoma in mice and is ubiquitously activated in the human disease

por Cigliano, Antonio, Zhang, Shanshan, Ribback, Silvia, Steinmann, Sara, Sini, Marcella, Ament, Cindy E., Utpatel, Kirsten, Song, Xinhua, Wang, Jingxiao, Pilo, Maria G., Berger, Fabian, Wang, Haichuan, Tao, Junyan, Li, Xiaolei, Pes, Giovanni M., Mancarella, Serena, Giannelli, Gianluigi, Dombrowski, Frank, Evert, Matthias, Calvisi, Diego F., Chen, Xin, Evert, Katja
Publicado 2023

The Hippo pathway effector TAZ induces intrahepatic cholangiocarcinoma in mice and is ubiquitously activated in the human disease

por Cigliano, Antonio, Zhang, Shanshan, Ribback, Silvia, Steinmann, Sara, Sini, Marcella, Ament, Cindy E., Utpatel, Kirsten, Song, Xinhua, Wang, Jingxiao, Pilo, Maria G., Berger, Fabian, Wang, Haichuan, Tao, Junyan, Li, Xiaolei, Pes, Giovanni M., Mancarella, Serena, Giannelli, Gianluigi, Dombrowski, Frank, Evert, Matthias, Calvisi, Diego F., Chen, Xin, Evert, Katja
Publicado 2022

Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans

por Che, Li, Chi, Wenna, Qiao, Yu, Zhang, Jie, Song, Xinhua, Liu, Ye, Li, Lei, Jia, Jiaoyuan, Pilo, Maria G, Wang, Jingxiao, Cigliano, Antonio, Ma, Zhilong, Kuang, Wenhua, Tang, Zefang, Zhang, Zemin, Shui, Guanghou, Ribback, Silvia, Dombrowski, Frank, Evert, Matthias, Pascale, Rosa Maria, Cossu, Carla, Pes, Giovanni Mario, Osborne, Timothy F, Calvisi, Diego F, Chen, Xin, Chen, Ligong
Publicado 2020